Results 41 to 50 of about 57,119,191 (293)
AAPS OpenCurcumin and paclitaxel are widely used as anti-tumor hydrophobic model drugs for the designation of smart tumor-targeting nanocarriers and the study of the correlation between structural characteristics of nanoparticles and in vivo therapeutic efficacy.
Hailing Tang +3 more
doaj +1 more source
Research on heart failure in Colombia, time to take a step forward
Revista de la Facultad de Medicina, 2018 Cardiovascular diseases are the leading cause of death worldwide. According to the Ministry of Health, in Colombia, cardiac ischemic disease ranks first, followed by stroke, diabetes and hypertensive heart disease, which are in the top ten sources of ...
Guillermo Mora Pabón
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Good practices on open access publications of projects funded by Horizon 2020
BiD: Textos Universitaris de Biblioteconomia i DocumentacióThis study aimed to analyse the results of open access publishing policies established for projects funded by the European Union's Horizon 2020 programme.
Elena Pastor Ramon +2 more
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FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Clinical research and sampling in the scientific: Research work [PDF]
Sestrinska reč, 2015 The survey is used to verify existing knowledge, to extend or discover a previously unknown knowledge, with the aim to come to the knowledge in the most efficient manner.
Peličić Damir +3 more
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FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
SPECIFICS OF SCIENTIFIC RESEARCH WORK IN HUMANITIES
Pravo, 2008 Methodology of scientific research work represents a sort of treusary of experiences till date of scientists from various fields. The refore, many topics remained outside the scope of this paper. On the other hand, the basic issues of methodology (method
Lynne Montgomery +2 more
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Group mentoring of youth scientists to enhance the students’ research literacy
Journal of Community Service and Empowerment, 2023 The Youth Scientific Group (YSG) is an extracurricular activity that has a positive impact on students. Unfortunately, the presence of YSG in various schools, including SMAN 1 Tumpang, is still not optimal. In this high school located in Malang Regency,
Ahmad Fauzi +5 more
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