Results 121 to 130 of about 9,382,254 (295)

Directions for Developing the Efficiency of Scientific Research

Revista Română de Biblioteconomie și Știința Informării, 2019
The article surprises elements of novelty and needs in the activity of scientific research and communication, identifies the needs and their practical settlement.
Ionela Maria Bârsan
doaj  

African Small Mammals (Macroscelidea and Rodentia) Housed at the National Museum of Natural History and Science (University of Lisbon, Portugal)

Diversity
The National Museum of Natural History and Science holds a historical collection of 279 small African mammal specimens (Macroscelidea and Rodentia), representing 32 species, gathered during the Portuguese colonial period in Mozambique, Angola, and Guinea-
Maria da Luz Mathias, Rita I. Monarca
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Active scientific research management model and optimization decision mechanism based on big data

大数据, 2019
During the scientific research management,a large number of data could be accessed from researchers,projects,output and other multi-dimensional.The big data of scientific research management implicitly contains tremendous highlyinterconnected knowledge ...
Ruili LUO, Yuanzhuo WANG
doaj  

Australian Sheep Industry CRC: Economic Evaluations of Scientific Research Programs [PDF]

By the end of its seven-year term in 2007-08, the Australian Sheep Industry CRC (Sheep CRC) will have received total funds of about $90 million, that comprises Commonwealth and industry funding of $30 million, and in-kind contributions valued at $60 ...
Griffith, Garry R., Silvester, Luke T., Vere, David T.   +2 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Poster on the wall: My stint as a scientific committee member [PDF]

Malaysian Family Physician
Suzane Chin Shiyun
doaj   +1 more source

Scientific excellence and extramural research grants: Beggars can't be choosers? [PDF]

Several reviews and impact assessment studies have concluded that the Sixth Framework Programme for Research and Technological Development (FP6) succeeded in fostering scientific excellence and attracting the 'A Team' in public science.
Grimpe, Christoph
core