Results 1 to 10 of about 95,141 (285)
Scleroderma with Nodular Scleroderma [PDF]
Case Reports in Dermatology, 2016 Background: Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type.
Chutika Srisuttiyakorn +1 more
doaj +3 more sources
Scleroderma and scleroderma-like syndromes
Frontiers in ImmunologySystemic sclerosis is a systemic connective tissue disease whose main pathophysiological mechanism is a progressive fibrosis of internal organs and skin leading to thickening and induration. Blood vessels may also be involved.
Katarzyna Romanowska-Próchnicka +4 more
doaj +3 more sources
AIMS Allergy and Immunology, 2021 Toll-like receptors (TLRs) are essential defensive mediators implicated in immune diseases. Tight regulation of TLR function is indispensable to avoid the damaging effects of chronic signaling.
Swarna Bale +2 more
doaj +1 more source
Infections of scleroderma digital ulcers: a single center cohort retrospective study
Dermatology Reports, 2021 BACKGROUNDS: Systemic Sclerosis (SSc) is a complex autoimmune and up to fifty percent of patients develop digital ulcers. AIMS: Understand how much infections influence scleroderma digital ulcers’ healing.
Dilia Giuggioli +7 more
doaj +1 more source
A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]
, 2015 In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Abraham, D +11 more
core +12 more sources
P058 A case of anti-Ku myositis/scleroderma overlap syndrome presenting with decompensated heart failure [PDF]
Rheumatol Adv PractClare Shere +3 more
europepmc +3 more sources
Pharmaceuticals, 2022 The role of Bronchoalveolar Lavage (BAL) in the evaluation of systemic sclerosis (SSc) interstitial lung disease (ILD) is still controversial. The aim of this systematic literature review was to investigate the use of BAL in SSc-ILD, and to focus on the ...
Martina Orlandi +8 more
doaj +1 more source
Correction to: Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis
Arthritis Research & Therapy, 2021 An amendment to this paper has been published and can be accessed via the original article.
David A. Fox +14 more
doaj +1 more source
Lymphocyte subset abnormalities in early diffuse cutaneous systemic sclerosis
Arthritis Research & Therapy, 2021 Background Abnormalities in lymphocyte surface markers and functions have been described in systemic sclerosis (SSc), but conflicting results abound, and these studies often examined patients with heterogeneous disease duration, severity, clinical ...
David A. Fox +14 more
doaj +1 more source
Nature Communications, 2022 A20 gene variants are linked with systemic sclerosis (SS), but the mechanisms are unclear. Here, the authors show that A20 expression is reduced in SS skin and lungs, that its ablation in mice induces SS, and that show that fibrosis can be ameliorated by
Wenxia Wang +23 more
doaj +1 more source