Scleroderma with Nodular Scleroderma [PDF]
Background: Nodular scleroderma is a rare variant of scleroderma which can occur in connection with systemic sclerosis or morphea. A biopsy from the lesion can demonstrate the scleroderma pattern, i.e., keloid pattern or mixed type.
Chutika Srisuttiyakorn +1 more
doaj +4 more sources
Checkpoint Inhibitor-Associated Scleroderma and Scleroderma Mimics [PDF]
Immune checkpoint inhibitors (ICI) are the standard of care for various malignancies and have been associated with a wide spectrum of complications that are phenotypically akin to primary autoimmune diseases.
Michael Macklin +3 more
doaj +2 more sources
Scleroderma (systemic sclerosis) is a complex disease in which extensive fibrosis, vascular alterations, and autoantibodies against various cellular antigens are among the principal features There are two major subgroups in the commonly accepted classification of scleroderma: limited cutaneous scleroderma and diffuse cutaneous scleroderma.
Gabrielli A. +2 more
core +6 more sources
Scleroderma and scleroderma-like syndromes
Systemic sclerosis is a systemic connective tissue disease whose main pathophysiological mechanism is a progressive fibrosis of internal organs and skin leading to thickening and induration. Blood vessels may also be involved.
Katarzyna Romanowska-Próchnicka +4 more
doaj +3 more sources
Collections in Institutional Herbaria listed as Rhizopogon, but not belonging to this genus [PDF]
Fifty-five collections misidentified and stored in various institutional herbaria, under severa1 Rhizopogon species narnes, are revised. Among these, twelve belong to Ascomycotina and 9 were identified to species level; the other collections, immature ...
Martín Esteban, María Paz
core +6 more sources
Hand disease in scleroderma: a clinical correlate for chronic hand transplant rejection [PDF]
Chronic rejection remains a potential long-term consequence of hand composite tissue allotransplantation (CTA). Scleroderma has already been proposed as a model for chronic facial allograft rejection based on potential parallels of observed progression ...
Puri, A +6 more
core +1 more source
Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients [PDF]
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R +17 more
core +1 more source
A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis. [PDF]
In scleroderma (systemic sclerosis, SSc), persistent activation of myofibroblast leads to severe skin and organ fibrosis resistant to therapy. Increased mechanical stiffness in the involved fibrotic tissues is a hallmark clinical feature and a cause of ...
Ayuko Takahashi (789901) +35 more
core +1 more source
Renal perfusion in scleroderma patients assessed by microbubble-based contrast-enhanced ultrasound [PDF]
OBJECTIVES: Renal damage is common in scleroderma. It can occur acutely or chronically. Renal reserve might already be impaired before it can be detected by laboratory findings.
Himsel, Andrea +12 more
core +1 more source
Development of the optimal touchscreen interface for patients with scleroderma
Impaired hand function is a major contributor to overall disability and reduced health-related quality of life in scleroderma patients. A relevant issue concerns interaction of scleroderma subjects with touchscreen interfaces.
Germani M. +8 more
core +1 more source

