Results 31 to 40 of about 56,738 (264)

Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group [PDF]

, 2012
INTRODUCTION: Erectile dysfunction (ED) is common in men with systemic sclerosis (SSc) but the demographics, risk factors and treatment coverage for ED are not well known.
Smith, Vanessa, Alan Tyndall, Garcia de la Peña Lefebvre, Paloma, Edoardo Rosato, Vanessa Smith, Jean Sibilia, Ingo Tarner, Gabriela Riemekasten, Ulrich A. Walker, Walid Abdel Atty Mohamed, Himsel, Andrea, Piotr Wiland, Rednic, Simona, Morović-Vergles, Jadranka, Andrea Himsel, Jose Pereira Da Silva, Allanore, Yannick, Jadranka Morovic Vergles, Anna T. Onken, Starovojtova M. Nikolaevna, Walker, Ulrich A., Farge-Bancel, Dominique, Dominique Farge Bancel, Tarner, Ingo, Mohamed, Walid Ahmed Abdel Atty, Paloma De La Pena Lefebvre, Paolo Airo, Riemekasten, Gabriela, Walker, Ulrich A, Onken, Anna Theresa, Tyndall, Alan, de la Peña Lefebvre, Paloma G., Chingching Foocharoen, Onken, Anna T, Stamenkovic, Bojana, Caramaschi, Paola, Rosato, Edoardo, Airó, Paolo, Dominique Farge-Bancel, Simona Rednic, Wiland, Piotr, Pereira da Silva, José António, Sibilia, Jean, Nikolaevna, Starovojtova M, Paola Caramaschi, Nikolaevna, Starovojtova M., Bojana Stamenkovic, Foocharoen, Chingching, Hachulla, Eric, Thomas Hugle, Distler, Oliver, Ulrich A Walker, Yannick Allanore, Stamenkovic, Bojan, Abdel Atty Mohamed, Walid A., Hügle, Thomas, Jadranka Morović-Vergles, et al, Pereira da Silva, José A., Starovojtova M Nikolaevna, Eric Hachulla, Anna T Onken, Oliver Distler   +62 more
core   +1 more source

From Localized Scleroderma to Systemic Sclerosis: Coexistence or Possible Evolution

Dermatology Research and Practice, 2018
Background. Systemic sclerosis (SSc) and localized scleroderma (LoS) are two different diseases that may share some features. We evaluated the relationship between SSc and LoS in our case series of SSc patients. Methods.
Giuggioli Dilia, Colaci Michele, Cocchiara Emanuele, Spinella Amelia, Lumetti Federica, Ferri Clodoveo   +5 more
doaj   +1 more source

Adipocyte-specific Repression of PPAR-gamma by NCoR Contributes to Scleroderma Skin Fibrosis

Arthritis Research & Therapy, 2018
Background A pivotal role for adipose tissue homeostasis in systemic sclerosis (SSc) skin fibrosis is increasingly recognized. The nuclear receptor PPAR-γ is the master regulator of adipogenesis.
Benjamin Korman, Roberta Goncalves Marangoni, Gabriel Lord, Jerrold Olefsky, Warren Tourtellotte, John Varga   +5 more
doaj   +1 more source

Exploring Sources of Emotional Distress among People Living with Scleroderma: A Focus Group Study. [PDF]

PLoS ONE, 2016
BACKGROUND:Systemic sclerosis, or scleroderma, is a chronic and rare connective tissue disease with negative physical and psychological implications. Sources of emotional distress and the impact they have on the lives of people with scleroderma are not ...
Stephanie T Gumuchian, Sandra Peláez, Vanessa C Delisle, Marie-Eve Carrier, Lisa R Jewett, Ghassan El-Baalbaki, Catherine Fortune, Marie Hudson, Ann Impens, Annett Körner, Jennifer Persmann, Linda Kwakkenbos, Susan J Bartlett, Brett D Thombs   +13 more
doaj   +1 more source

Fibrosing arthropathy in juvenile scleroderma

Современная ревматология, 2021
The group of scleroderma diseases includes a number of clinical entities, the main symptom of which is skin tightening. Scleroderma is a prominent example of these diseases, characterized by excessive synthesis and deposition of collagen in organs and ...
D. A. Dibrov, M. N. Starovoitova, O. V. Desinova   +2 more
doaj   +1 more source

Scleroderma with crescentic glomerulonephritis: a case report

Journal of Medical Case Reports, 2008
Introduction Systemic sclerosis or scleroderma is an autoimmune rheumatic disease characterized by organ-based fibrosis. Renal involvement in scleroderma occurs mainly in the form of scleroderma renal crisis, affecting 5 to 10% of patients.
Ramaswami Arunachalam, Kandaswamy Thiraviam, Rajendran Tholappan, Jeyakrishnan Kizhake, Aung Hla, Iqbal Mohammaed, Jacob Chakko K, Zinna Haji, Kafeel Gazala   +8 more
doaj   +1 more source

Preliminary safety and efficacy profile of prucalopride in the treatment of systemic sclerosis (SSc)-related intestinal involvement: results from the open label cross-over PROGASS study

Arthritis Research & Therapy, 2017
Background Prokinetics are used to treat enteric dismotility symptoms in systemic sclerosis (SSc) patients, but they often lack adequate efficacy. The most effective prokinetics belonging to the serotonin (5-HT4) receptor agonists class were withdrawn ...
Barbara Vigone, Monica Caronni, Adriana Severino, Chiara Bellocchi, Anna Rita Baldassarri, Mirella Fraquelli, Gaia Montanelli, Alessandro Santaniello, Lorenzo Beretta   +8 more
doaj   +1 more source

Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome – description of two cases [PDF]

, 2016
Systemic sclerosis (Ssc) is an autoimmune connective tissue disease of unknown origin, characterized by progressive fibrosis of the skin and internal organs.
Robert Rudny, Magdalena Marek
core   +1 more source

Immunoregulatory Role of HLA-G in Allergic Diseases

Journal of Immunology Research, 2016
Allergic diseases are sustained by a T-helper 2 polarization leading to interleukin-4 secretion, IgE-dependent inflammation, and mast cell and eosinophil activation.
Giuseppe Murdaca, Paola Contini, Simone Negrini, Giorgio Ciprandi, Francesco Puppo   +4 more
doaj   +1 more source

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients

, 2001
Patients with scleroderma receiving Iloprost as a treatment for severe Raynaud's phenomenon report a reduction in skin tightness, suggesting that this drug inhibits skin fibrosis.
Stratton, R, Thomas Haberberger, Carol M. Black, Haberberger, T, Xu Shiwen, Martini, G, Holmes, A, Alan Holmes, Andrew Leask, Shiwen, X, David Abraham, Black, CM, Leask, A, Martin, GR, Abraham, D, George R. Martin, Richard Stratton, Giorgia Martini   +17 more
core   +1 more source