Results 11 to 20 of about 274,582 (186)
Detection of autoimmune antibodies in localized scleroderma by synthetic oligonucleotide antigens. [PDF]
In this study, we developed a series of synthetic oligonucleotides that allowed us to investigate the details on the antigen recognition by autoimmune antibodies in localized scleroderma subjects.
Simone Samuelsen+4 more
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Localized scleroderma in children
Localized scleroderma is an autoimmune disease affecting the dermis and underlying tissues (subcutaneous tissue, fascia, muscles, bones). The disease mainly occurs in women aged 20–50 years; however, children aged 7–10 years represent about 15% of all ...
Katarzyna A. Wolska-Gawron+1 more
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Systemic sclerosis with keloidal nodules [PDF]
Nodular sclerosis is a rare form of presentation related to both systemic and localized forms of scleroderma. We describe the case of a patient with nodular sclerosis in order to alert the medical community to recognize this entity.
Bárbara Stadler+4 more
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Background and Design: Morphea is also known as localized scleroderma. It is a rare autoimmune skin disease characterized by inflammation and sclerosis in the dermis and sometimes in the subcutaneous tissue.
Yıldız Gürsel Ürün+1 more
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Localized scleroderma – current treatment options
Localized scleroderma (morphea) is a connective tissue disease that affects the skin, subcutaneous tissue and underlying tissues including the fasciae, muscles and bones. The treatment of localized scleroderma depends on the clinical form of the disease,
Katarzyna Wolska-Gawron+2 more
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Localized scleroderma secondary to mixed connective tissue disease during abatacept therapy
A 47‐year‐old woman with mixed connective tissue disease was treated with abatacept. After 2 months, a 3‐cm depression with atrophied surface was observed on her back, which had histopathological consistent with the symptoms of localized scleroderma ...
Sayuko Nagaoka+2 more
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Background: Linear atrophoderma of Moulin (LAM) is a dermatosis that affects children and adolescents characterized by hyperpigmented and atrophic linear lesions following Blaschko lines. So far, less than 50 cases have been published. Therefore, it is a
Eduardo Marín-Hernández+2 more
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Antinuclear Antibodies in Localized Scleroderma [PDF]
AbstractWhen HeLa cells were used as the substrate for detection by the indirect immunofluorescence method, antinuclear antibodies were demonstrated in 16 of 22 (72.7%) sera from patients with localized scleroderma. When mouse kidney sections were used, the positive rate for antinuclear antibodies was 50% (11 of 22).
Yasuharu Nakabayashi+3 more
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Localized scleroderma is a rare auto-immune disorder characterized by inflammation and fibrosis of the skin and subcutaneous fat in the affected area, leaving aesthetic impairment to the patients.Such patients often seek plastic surgery for the treatment.
WANG Chenyu+4 more
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Effective options in the quiescent, scantily inflammatory phase of localized scleroderma (morphea) are lacking. A cohort study in patients with histologically confirmed fibroatrophic morphea explored the therapeutic value of the anti-dystrophic A2A ...
Maurizio Romagnuolo+5 more
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