Results 51 to 60 of about 1,415,478 (254)

Localized scleroderma en coup de sabre in the Neurology Clinic [PDF]

, 2016
Background: Localized scleroderma en coup de sabre (LScs) is a form of localized scleroderma thought to be an autoimmune disorder. Central nervous system involvement is not rare and neurological manifestations include seizures, focal neurological ...
Cerqueira, João José, Fernandes, João Soares, Lourenço, Esmeralda, Macedo, Cristiana, Maré, Ricardo, Pereira, João, Pinho, João, Rocha, João, Sousa, Filipa   +8 more
core   +1 more source

Laser therapy in superficial morphea lesions – indications, limitations and therapeutic alternatives [PDF]

, 2020
Morphea or localized scleroderma is an uncommon autoimmune and inflammatory disease which affects patients of any age. Even if morphea lesions present systemic symptoms as myalgias or arthritis, it is distinct from systemic sclerosis because it does not ...
Ardeleanu, Valeriu, Constantin, Vlad Denis, Radaschin, Diana Sabina, Stana, Paunica, Tatu, Alin Laurentiu   +4 more
core   +1 more source

Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests [PDF]

, 2013
INTRODUCTION: Microcirculation dysfunction is a typical feature of systemic sclerosis (SSc) and represents the earliest abnormality of primary myocardial involvement.
CAULI, ALBERTO, Garau P, Iliceto S, MATHIEU, ALESSANDRO, MELONI, LUIGI, MONTISCI, ROBERTA, PIGA, MATTEO, Ruscazio M, Siotto P, VACCA, ALESSANDRA   +9 more
core   +1 more source

Localized scleroderma: A rare clinical entity

Journal of Indian Academy of Oral Medicine and Radiology, 2014
Localized Scleroderma (LS), which is also referred to as morphea, is an inflammatory disease that leads to diffuse or localized fibrotic and atrophic skin hardening.
Ranjana Garg, Swati Dhingra, Ravneet Arora   +2 more
doaj   +1 more source

Intramuscular Polydeoxyribonucleotides in Fibrotic and Atrophic Localized Scleroderma: An Explorative Prospective Cohort Study

Biomedicines, 2023
Effective options in the quiescent, scantily inflammatory phase of localized scleroderma (morphea) are lacking. A cohort study in patients with histologically confirmed fibroatrophic morphea explored the therapeutic value of the anti-dystrophic A2A ...
Maurizio Romagnuolo, Chiara Moltrasio, Angelo Valerio Marzano, Gianluca Nazzaro, Simona Muratori, Sebastiano Recalcati   +5 more
doaj   +1 more source

Single-cell transcriptome conservation in a comparative analysis of fresh and cryopreserved human skin tissue: pilot in localized scleroderma

Arthritis Research & Therapy, 2020
Background The purpose of this study was to assess variability in cell composition and cell-specific gene expression in the skin of patients with localized scleroderma (LS) utilizing CryoStor® CS10 in comparison to RPMI to produce adequate preservation ...
E. Mirizio, T. Tabib, Xinjun Wang, Wei Chen, Christopher Liu, R. Lafyatis, Heidi Jacobe, K. Torok   +7 more
semanticscholar   +1 more source

PPAR? Downregulation by TGF in Fibroblast and Impaired Expression and Function in Systemic Sclerosis: A Novel Mechanism for Progressive Fibrogenesis [PDF]

, 2010
The nuclear orphan receptor peroxisome proliferator-activated receptor-gamma (PPAR-γ) is expressed in multiple cell types in addition to adipocytes. Upon its activation by natural ligands such as fatty acids and eicosanoids, or by synthetic agonists such
A Galli, A Kis, A Milano, AK Ghosh, AK Ghosh, AK Ghosh, AK Ghosh, Asish K. Ghosh, BC Willis, BM Psaty, C Beyer, C Dong, Carol Feghali-Bostwick, DA Culver, ED Rosen, ED Rosen, F Verrecchia, F Zheng, G Lakos, H Ha, HA Burgess, J Berger, J Varga, J Varga, JE Milam, Jennifer L. Sargent, JL Sargent, John Varga, Joy Sturtevant, JT Tan, Jun Wei, KA Longo, Kazuhiro Komura, KM Hong, L Fajas, L Yang, LS Higgins, M Dudas, M Kapoor, M Kapoor, M Lehrke, M Trojanowska, M Wu, Manu Jain, MF Simon, Michael L. Whitfield, Minghua Wu, OA Gressner, P Karnik, P Tontonoz, Qi-Quan Huang, R Fleischmajer, S Dennler, S Kim, S Sonnylal, S Zheng, SE Ross, SH Liu, SJ Chen, SZ Duan, T Kawai, T Miyahara, T Shiomi, TM McIntyre, V Zoete, W Yuan, X Li, X Liu, X Shi-wen, X Tan, Y Mori, Y Mori, Y Park, Y Shi, Y Wang, Z Yun   +75 more
core   +4 more sources

Juvenile localized scleroderma: clinical picture, diagnosis, therapeutic update (literature review and own observations)

Zdorovʹe Rebenka, 2019
Among rheumatic diseases in children, a special place belongs to juvenile localized scleroderma, which is highlighted as a separate form in the structure of scleroderma diseases and is characterized by: the onset of the disease up to 16 years, skin ...
L.F. Bogmat, V.V. Nikonova
doaj   +1 more source

Systemic sclerosis: current views of its pathogenesis. [PDF]

, 2003
Systemic sclerosis (SSc) is an autoimmune disorder of unknown etiology characterized by severe and often progressive cutaneous and visceral fibrosis, pronounced alterations in the microvasculature, and numerous cellular and humoral immune abnormalities ...
Derk, Chris T., Jimenez, Sergio A.
core   +2 more sources

Localized Scleroderma, Systemic Sclerosis and Cardiovascular Risk: A Danish Nationwide Cohort Study

Acta Dermato-Venereologica, 2017
Recent findings indicate that patients with systemic sclerosis have an increased risk of cardiovascular disease. To determine whether patients with systemic sclerosis or localized scleroderma are at increased risk of cardiovascular disease, a cohort ...
Jeanette Halskou Hesselvig, Kristian Kofoed, Jashin J. Wu, Lene Dreyer, Gunnar Gislason, Ole Ahlehoff   +5 more
doaj   +1 more source