Off-Label Use of Topical Ruxolitinib in Dermatology: A Systematic Literature Review and Current Perspectives. [PDF]
JAK inhibitors are used to treat various inflammatory skin diseases. However, systemic formulations are associated with an increased risk of major adverse events.
Spadafora M +5 more
europepmc +4 more sources
Consensus statement on the diagnosis and treatment of sclerosing diseases of the skin, Part 2, Scleromyxoedema and scleroedema [PDF]
The term 'sclerosing diseases of the skin' comprises specific dermatological entities, which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement ...
Knobler, Robert, Sunderkötter, Cord
core +8 more sources
Combination intravenous immunoglobulin, oral prednisone, and methotrexate for managing scleromyxedema: case report and literature discussion [PDF]
Scleromyxedema (SMX), the generalized and sclerodermic form of lichen myxedematous (LM), is a chronic mucinosis characterized by cutaneous manifestation and several systemic comorbidities.
Gaia Fasano +3 more
doaj +2 more sources
Scleromyxedema: An atypical case
Scleromyxedema is a rare, chronic and persistent idiopathic disorder characterized by a generalized papular eruption due to dermal mucin deposition with an increase in dermal collagen. Patients usually have associated paraproteinemia.
Emy Thomas +3 more
doaj +3 more sources
Unusual Cutaneous Manifestations in a Patient with a History of Hepatitis B: A Case of Scleromyxedema and Literature Review [PDF]
Aili Gao, Xin Tian, Dexiu Lang, Yue Chen Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, Guangdong, People’s Republic of ChinaCorrespondence: Yue Chen, Department of Dermatology, Guangzhou Dermatology Hospital, Guangzhou, People’s ...
Gao A, Tian X, Lang D, Chen Y
doaj +2 more sources
Granulomatous variant of scleromyxedema successfully treated with topical ruxolitinib, dapsone and intravenous immunoglobulin [PDF]
Donglin Zhang, BA +5 more
doaj +2 more sources
Hyalase in Dermatology: Applications Beyond Filler Management. [PDF]
ABSTRACT Background Hyaluronic acid (HA) is a key extracellular matrix component in the skin. Hyaluronidase is an enzyme that breaks down HA into monosaccharides. The FDA has approved this enzyme for hypodermoclysis, drug absorption enhancement, and subcutaneous urography.
Hasanzadeh S +6 more
europepmc +2 more sources
Sclerosing diseases of the skin. [PDF]
Summary Sclerosing skin diseases comprise a group of distinct dermatological conditions characterized by fibrotic changes that may severely impair patients’ quality of life. These conditions often present with cutaneous manifestations and, in some cases, may extend to extracutaneous tissues, potentially resulting in significant morbidity and mortality.
Kalantari Y +4 more
europepmc +2 more sources
Discrete papular lichen myxedematosus successfully treated with isotretinoin [PDF]
Alexa Figueroa Baiges, BS +2 more
doaj +2 more sources
SummaryScleromyxedema is a rare, cutaneous deposition disorder from the group of mucinoses, which can affect multiple organs and is virtually always associated with a monoclonal gammopathy. Cutaneous manifestations are usually generalized, 2 to 3 mm sized, dome‐shaped or flat‐topped, waxy, slightly red to skin‐colored papules and sclerodermoid ...
Jochen H O, Hoffmann, Alexander H, Enk
openaire +4 more sources

