Results 51 to 60 of about 1,097,866 (354)

Systemic sclerosis

The Lancet, 2023
Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium.
Volkmann, Elizabeth R, Andréasson, Kristofer, Smith, Vanessa   +2 more
openaire   +4 more sources

The Impact of Tilburg Frailty on Poststroke Fatigue in First‐Ever Stroke Patients: A Cross‐Sectional Study With Unified Measurement Tools and Improved Statistics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Poststroke fatigue (PSF) and frailty share substantial overlap in their manifestations, yet previous research has yielded conflicting results due to the use of heterogeneous frailty assessment tools. Objective To evaluate the independent impact of frailty on PSF using a unified measurement system (Tilburg Frailty Indicator, TFI ...
Chuan‐Bang Chen, Xiao‐Xue Wang, Shao‐Rui Bao, Sui‐Li Lin, Mei‐Chun Shu, Xi‐Xi Ye, Wen‐Jie Cong   +6 more
wiley   +1 more source

Enfermedad poliquística del hígado Polcystic disease of the liver

Revista Colombiana de Cirugía, 2008
Introducción. La enfermedad poliquística del hígado es una enfermedad de predominio en la mujer, en la cual se encuentran múltiples quistes en el hígado y el riñón que producen síntomas por su crecimiento y efecto de masa. Materiales y métodos.
Héctor René Hazbón
doaj  

Tibial deformities caused by focal fibrocartilaginous dysplasia: a narrative review

Frontiers in Pediatrics
Focal fibrocartilaginous dysplasia (FFCD) of the tibia is a rare but well-recognised, “tumour-like” condition that primarily involves the proximal tibia and causes tibial deformities.
Dimitri Fasel, Elio Paris, Victor Aye, Maxime Pilloux, Giacomo De Marco, Oscar Vazquez, Christina Steiger, Romain Dayer, Nathaly Gavira, Dimitri Ceroni   +9 more
doaj   +1 more source

EndoTHeF: Endoluminal Treatment of Hemorrhoids with Foam [PDF]

Iranian Journal of Colorectal Research, 2018
Background: Hemorrhoids are normal anatomical structures, present in individuals from birthandrecognisable even in intrauterinelife. When we talk about haemorrhoids in actual fact we refer to the symptoms caused by haemorrhoids.
Maurizio Ronconi, Silvia Casiraghi, Mattia Schieppati   +2 more
doaj  

Amyotrophic Lateral Sclerosis [PDF]

, 2019
The word amyotrophic is derived from Greek, and means “without nourishment to muscles”, lateral means to the sides and sclerosis means hardened (“What is ALS?,” n.d.).
Georgetson, Anastasia M.
core   +1 more source

JC virus-DNA detection is associated with CD8 fffector accumulation in peripheral blood of patients with multiple sclerosis under natalizumab treatment, independently from JC virus serostatus [PDF]

, 2018
Although natalizumab (anti-α4 integrin) represents an effective therapy for relapsing remitting multiple sclerosis (RRMS), it is associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML), caused by the polyomavirus ...
Anzivino, Elena, Ciardi, Maria R., Cortese, Antonio, D’Abramo, Alessandra, Francia, Ada, Frontoni, Marco, Iannetta, Marco, Lichtner, Miriam, Mastroianni, Claudio M., Morreale, Manuela, Oliva, Alessandra, Pietropaolo, Valeria, Pontecorvo, Simona, Prezioso, Carla, Rodio, Donatella Maria, Vullo, Vincenzo, Zingaropoli, Maria A.   +16 more
core   +3 more sources

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Contribution of irreversible morphological changes of different renal structures to development of anemia in immune glomerulopathies

Терапевтический архив, 2008
Aim. To find out correlations between severity of sclerotic affection of the glomeruli, tubules, interstitium, vessels and development of anemia in patients with glomerulopathy. Material and methods.
V A Dobronravov, V G Sipovskiĭ, I I Trofimenko, A V Dobronravov, I K Klemina, V A Titova, E B Sipovskaia, A V Smirnov   +7 more
doaj  

Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]

, 2018
Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent, Hollenbach, Jill, Misra, Maneesh   +2 more
core   +1 more source