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The primary focus of the current study was to confirm the presence of scopoletin as a novel metabolite in Iraqi Eichhornia crassipes. Since there are currently no studies on Iraqi E. crassipes coumarins, particularly scopoletin, in the literature survey,
Thukaa , Z Abdul-Jalil, Sura, Hamid Abid
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Alcoholic and watery extracts prepared from crude drugs of Helichrysum italicum (Roth) Don and Helichrysum stoechas (L.) Moench (Asteraceae), obtained from the italian herbal market, were analyzed to evaluate the scopoletin content.
DONINI, Arnaldo +6 more
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TLC-densitometric Determination of Scopoletin in Cortex Lycii
本文用双波长薄层扫描法首次测定了5种商品地骨皮药材中莨菪亭(SCOPOlETIn)的含量,以山西产地骨皮(lyCIuMCHInEnSEMIll.)的含量最高。The paper reported the content of scopoletin in 5 kinds of Cortex Lycii by TLC-densitometric determination For the First time.The results showed that the sample of the highest
王强, 周兴旺, 徐国钧
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Effect of scopoletin on lipoprotein lipase activity in 3T3-L1 adipocytes
Hypertriglyceridemia is an independent risk factor of cardiovascular diseases. It is caused by the imbalance between hepatic triglyceride production and peripheral removal.
Chi, Myung S. +7 more
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On the Determination of Scopoletin in Aged Distilled Liquors [PDF]
OTSUKA, Ken-ichi, ZENIBAYASHI, Yutaka
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Design, synthesis and cytotoxic activities of scopoletin-isoxazole and scopoletin-pyrazole hybrids
Bioorganic and Medicinal Chemistry Letters, 201712 novel scopoletin-isoxazole and scopoletin-pyrazole hybrids were designed, synthesized and their chemical structures were confirmed by HR-MS, IR, 1H NMR and 13C NMR spectra. The anticancer activities of the newly synthesized compounds were evaluated in vitro against three human cancer cell lines including HCT-116, Hun7 and SW620 by MTT assay.
Li Chen, Jianbo Sun
exaly +3 more sources
Synthesis and anti-acetylcholinesterase activity of scopoletin derivatives
Bioorganic Chemistry, 2016A series of scopoletin derivatives incorporated with the pyridinium moiety was synthesized and evaluated for their acetylcholinesterase (AChE) inhibitory activity by the colorimetric Ellman's method. A 2-fluorobenzylpyridinium derivative was the most potent among the tested compounds, with an IC50 value of 0.215±0.015μM, which was greatly improved from
Patchreenart Saparpakorn +1 more
exaly +3 more sources
Synthesis and in vitro antitumor activity of novel scopoletin derivatives
Bioorganic and Medicinal Chemistry Letters, 2012Twenty scopoletin derivatives were developed by a systematic combinatorial chemical approach and their chemical structures were confirmed by MS, IR, (1)H NMR spectra and elemental analysis. Primary screening against mammary (MCF-7 and MDA-MB 231) and colon (HT-29) carcinoma cells indicated that five compounds (8d, 8g, 8j, 11b and 11g) displayed high ...
Ronald Gust, Wukun Liu, Jinpei Zhou
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Micro determination of scopoletin in Nicotiana tabacum
Phytochemistry, 1972Abstract A GLC method for quantitative analysis of tobacco for scopoletin (as free scopoletin and the glycoside, scopolin) utilizes tritium foil electron capture detection of as little as 100 ng scopoletin. Polyphenols are directly extracted with n-propanol, and hydrolyzed to produce scopoletin. After silylation the TMS-scopoletin is separated on 10%
R A Andersen
exaly +2 more sources

