Results 171 to 180 of about 9,314 (214)

Respiratory arrhythmias produced by purified scorpion toxin

Toxicon, 1973
Abstract Bilateral section of vagi nerves and denervation of carotid bodies prevented the gasping, ataxic and periodic respirations produced by purified scorpion toxin ( Tityus serrulatus ) in the rat. The apnea recorded in intact rats after toxin injection was of long duration in comparison with that observed in denervated animals.
L, Freire-Maia, A D, Azevedo, V P, Costa VAL   +2 more
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The antigenic structure of a scorpion toxin

Molecular Immunology, 1989
Scorpion toxins constitute a family of homologous proteins that exert potent pharmacological effects on ion channels. These proteins are immunogenic and constitute a good model for investigation of the molecular basis of antigenicity. In the first part of this article we summarize the results we have obtained in recent years concerning the location of ...
C, Granier, J, Novotny, J C, Fontecilla-Camps, P, Fourquet, M, el Ayeb, E, Bahraoui   +5 more
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SCORPION TOXIN‐INDUCED CATECHOLAMINE RELEASE FROM SYNAPTOSOMES

Journal of Neurochemistry, 1974
Abstract— A toxin purified from crude venom of the scorpion L. quinquestriatus releases [3H]norepinephrine from synaptosomes prepared from rat brain. The toxin‐induced release is dependent on duration of exposure and concentration of toxin in the medium.
J, Moss, R W, Colburn, I J, Kopin
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Scorpion Alpha-Toxins Lqh-2☆

2009
In deep review of the pharmacology and toxicology of scorpion toxin Lqh2.
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Scorpion toxins: Tools for studying K+ channels

Toxicon, 1998
Over the last period of time, a large number of scorpion toxins have been characterized. These peptidyl inhibitors of K+ channels have been very useful as probes for determining the molecular architecture of these channels, for purifying channels from native tissue and determining their subunit composition, for developing the pharmacology of K ...
M L, Garcia, M, Hanner, G J, Kaczorowski
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β-Scorpion toxins

1997
Abstract β-Toxins are responsible for the life hazard constituted, in Central and South America, by scorpion stings. They are qualitatively and quantitatively the most important polypeptides of the venom. They are made of one single polypeptide chain of 60 to 66 amino acid residues crosslinked by four disulfide bridges (Possani et al ...
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Scorpion toxin: Specific binding to rat synaptosomes

Biochemical and Biophysical Research Communications, 1978
Summary The protein neurotoxin II from the venom of the scorpion Androctonus australis Hector was labeled with 125I by the lactoperoxidase method to a specific radioactivity of about 100 μCi/μg without loss of biological activity. The labeled neurotoxin binds specifically to a single class of non interacting binding sites of high affinity (KD = 0 ...
E, Jover, N, Martin-Moutot, F, Couraud, H, Rochat   +3 more
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Scorpion toxins interact with nicotinic acetylcholine receptors

FEBS Letters, 2019
Neurotoxins are among the main components of scorpion and snake venoms. Scorpion neurotoxins affect voltage‐gated ion channels, while most snake neurotoxins target ligand‐gated ion channels, mainly nicotinic acetylcholine receptors (nAChRs). We report that scorpion venoms inhibit α‐bungarotoxin binding to both muscle‐type nAChR from Torpedo californica
Igor E. Kasheverov, Peter B. Oparin, Maxim N. Zhmak, Natalya S. Egorova, Igor A. Ivanov, Andrei M. Gigolaev, Oksana V. Nekrasova, Marina V. Serebryakova, Denis S. Kudryavtsev, Nikita A. Prokopev, Anh N. Hoang, Victor I. Tsetlin, Alexander A. Vassilevski, Yuri N. Utkin   +13 more
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Scorpion-Toxins Lqh-3

2010
In deep review on the pharmacology and toxicology of scorpion toxin Lqh3.
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Immunological Properties of Scorpion Toxins

2000
Early studies on scorpion venom were motivated by the problems of treating envenomation in various parts of the world (Goyffon et al.,1982; Freire-Maia et al.,1994; Dehesa-Davila et al., 1994). Over the last 30 years, there has been extensive work by our groups and others to elucidate the mechanism of envenomation and to fight against the noxious ...
Christiane Devaux, Mohamed El Ayeb
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