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Scorpion Venom: Detriments and Benefits [PDF]

open access: yesBiomedicines, 2020
Scorpion venom may cause severe medical complications and untimely death if injected into the human body. Neurotoxins are the main components of scorpion venom that are known to be responsible for the pathological manifestations of envenoming.
Shirin Ahmadi   +8 more
doaj   +6 more sources

Biochemical and Proteomic Characterization, and Pharmacological Insights of Indian Red Scorpion Venom Toxins [PDF]

open access: goldFrontiers in Pharmacology, 2021
The Indian red scorpion (Mesobuthus tamulus) is one of the world’s deadliest scorpions, with stings representing a life-threatening medical emergency. This species is distributed throughout the Indian sub-continent, including eastern Pakistan, eastern ...
Bhabana Das   +3 more
doaj   +4 more sources

Synergistic effect of Rhopalurus junceus scorpion venom combined with conventional cytostatics in cervical cancer cell line HeLa. [PDF]

open access: diamondJournal of Pharmacy & Pharmacognosy Research, 2019
Context: Venom from endemic scorpion of Cuba, Rhopalurus junceus, decreases the viability of epithelial cancer cells and has negligible cytotoxic effect on normal cells.
Arianna Yglesias-Rivera   +2 more
doaj   +3 more sources

Heteroctenus junceus Scorpion Venom Modulates the Concentration of Pro-Inflammatory Cytokines in F3II Tumor Cells [PDF]

open access: yesLife, 2023
The ability of Heteroctenus junceus scorpion venom to modulate the concentration of cytokines related to its antitumoral effect is unknown. F3II cells were treated with ¼ IC50, ½ IC50 and the IC50 of H. junceus scorpion venom.
Arianna Yglesias-Rivera   +3 more
doaj   +2 more sources

Potential of Scorpion (Scorpiops pseudomonatus) Venom in Diabetes Therapy: A Study on α-Amylase and α-Glucosidase Inhibition [PDF]

open access: diamondJournal of Liaquat National Hospital
Background: The increasing number of diabetes mellitus patients and the complications of its treatment using chemical medicine have made it necessary to look for new treatment options that can control blood glucose levels.
Syed Asif Nawaz   +4 more
doaj   +2 more sources

Transcriptome analysis of the venom gland of the Mexican scorpion Hadrurus gertschi (Arachnida: Scorpiones) [PDF]

open access: goldBMC Genomics, 2007
Background Scorpions like other venomous animals posses a highly specialized organ that produces, secretes and disposes the venom components. In these animals, the last postabdominal segment, named telson, contains a pair of venomous glands connected to ...
Rodríguez de la Vega Ricardo C   +3 more
doaj   +2 more sources

Evaluation of in vivo Lethality and in vitro Cytotoxic Effect of Odontobuthus bidentatus Scorpion Venom [PDF]

open access: yesArchives of Razi Institute, 2022
The results of numerous studies have revealed that some deadly scorpion venoms are composed of various bioactive molecules that have significant cytotoxic effects on cancer cells.
Z Salehi-Najafabadi   +2 more
doaj   +2 more sources

Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus [PDF]

open access: green, 2016
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Timoteo Olamendi‐Portugal   +6 more
openalex   +4 more sources

Unveiling the Diversity and Modifications of Short Peptides in Buthus martensii Scorpion Venom through Liquid Chromatography-High Resolution Mass Spectrometry [PDF]

open access: yesToxins
More recently, short peptides in scorpion venom have received much attention because of their potential for drug discovery. Although various biological effects of these short peptides have been found, their studies have been hindered by the lack of ...
Ling Zeng   +8 more
doaj   +2 more sources

F2 peptide fraction of Androctonus crassicauda scorpion venom: Inducing M2 to M1 macrophage polarization and inhibiting colon carcinoma cell proliferation and migration [PDF]

open access: yesAvicenna Journal of Phytomedicine
Objective: Colorectal cancer (CRC) is among the deadliest malignancies, often diagnosed at advanced stages, limiting treatment efficacy and necessitating alternative therapeutic approaches.
Noushin Ghadiri   +5 more
doaj   +2 more sources

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