Results 91 to 100 of about 5,167 (220)

Advances in the Role of Antimicrobial Peptides in the Management of Sexually Transmitted Infections

Journal of Clinical Laboratory Analysis, Volume 39, Issue 11, June 2025.
The article reviews recent advancements in the use of antimicrobial peptides (AMPs) for the treatment and prevention of sexually transmitted infections (STIs), with a particular focus on research progress in combating infections such as gonorrhea, HIV, HSV, and Chlamydia, as well as the challenges and future directions in this field.
Shuangwen Xiao, Wei Zuo, Qing Xiang, Yafeng Xie, Yongjian Xiao   +4 more
wiley   +1 more source

The action of red scorpion (Mesobuthus tamulus coconsis, pocock) venom and its isolated protein fractions on blood sodium levels

Journal of Venomous Animals and Toxins including Tropical Diseases, 2007
Red scorpion (Mesobuthus tamulus or Buthus tamulus) venom samples were collected at different regions of India: western (Chiplun and Ahmednagar from Maharashtra State) and southern (Ratnagiri and Chennai from Tamil Nadu State). The action of whole venoms
R. V. Badhe, A. B. Thomas, A. D. Deshpande, N. Salvi, A. Waghmare   +4 more
doaj   +1 more source

Pioneering Study on Rhopalurus crassicauda Scorpion Venom: Isolation and Characterization of the Major Toxin and Hyaluronidase

Frontiers in Immunology, 2020
Scorpionism is responsible for most accidents involving venomous animals in Brazil, which leads to severe symptoms that can evolve to death. Scorpion venoms consist of complexes cocktails, including peptides, proteins, and non-protein compounds, making ...
Caio B. Abreu, Karla C. F. Bordon, Felipe A. Cerni, Isadora S. Oliveira, Carla Balenzuela, Gabriel M. Alexandre-Silva, Karina F. Zoccal, Mouzarllem B. Reis, Mouzarllem B. Reis, Gisele A. Wiezel, Steve Peigneur, Ernesto L. Pinheiro-Júnior, Jan Tytgat, Tiago M. Cunha, Loic Quinton, Lúcia H. Faccioli, Eliane C. Arantes, Umberto Zottich, Manuela B. Pucca   +18 more
doaj   +1 more source

Identification and Characterization of a Novel GAPDH‐Derived Antimicrobial Peptide From Jellyfish

Journal of Peptide Science, Volume 31, Issue 4, April 2025.
A novel GAPDH‐derived peptide JFP‐2826, which showed selective antimicrobial activity against marine‐specific Vibrio bacteria, was identified from the transcriptome of Rhopilema esculentum. Jellyfish GAPDH may have a newly discovered antimicrobial‐related function conducted by releasing JFP‐2826‐like cryptic peptides. ABSTRACT Marine organisms serve as
Jingwen Liu, An Li, Yueyue Li, Jing Li, Xiaoyu Geng, Junyi Wan, Qianqian Lu, Qingqing Wang, Mingke Wang, Jishun Yang   +9 more
wiley   +1 more source

Interrogating stonefish venom: small molecules present in envenomation caused by Synanceia spp.

FEBS Open Bio, Volume 15, Issue 3, Page 399-414, March 2025.
Molecular analysis of Synanceia horrida (ShV) and S. verrucosa (SvV) venoms identified three small molecules new to stonefish venom: Gamma‐aminobutyric acid (GABA), choline, and 0‐acetylcholine. Analysis on human nicotinic acetylcholine (nAChRs) and GABAA receptors showed activation of neuronal (α7) and adult muscle‐type (α1β1δε) nAChRs by ShV, while ...
Silvia Luiza Saggiomo, Steve Peigneur, Jan Tytgat, Norelle L. Daly, David Thomas Wilson   +4 more
wiley   +1 more source

Antimicrobial and cytolytic peptides of venomous arthropods [PDF]

, 2018
As a response to invading microorganisms, the innate immune system of arthropods has evolved a complex arrangement of constitutive and inducible antimicrobial peptides that immediately destroy a large variety of pathogens.
Kuhn-Nentwig, L.
core  

Dissecting Toxicity: The Venom Gland Transcriptome and the Venom Proteome of the Highly Venomous Scorpion Centruroides limpidus (Karsch, 1879)

Toxins, 2019
Venom glands and soluble venom from the Mexican scorpion Centruroides limpidus (Karsch, 1879) were used for transcriptomic and proteomic analyses, respectively.
Jimena I. Cid-Uribe, Erika P. Meneses, Cesar V. F. Batista, Ernesto Ortiz, Lourival D. Possani   +4 more
doaj   +1 more source

Structural analysis of an Asterias rubens peptide indicates the presence of a disulfide‐directed β‐hairpin fold

FEBS Open Bio, Volume 15, Issue 3, Page 415-426, March 2025.
Sea stars have remarkable regenerative capabilities. A peptide, KASH2, identified in the biofluid of the common sea star Asterias rubens appears to be involved with the wound‐healing response in the organism. Here, we show the 3D structure of KASH2 adopts a disulfide‐directed β‐hairpin fold, a fold only previously found in arachnids, and does not show ...
Rozita Takjoo, David T. Wilson, Justine Le Quilliec, Casey A. Schmidt, Guangzu Zhao, Michael J. Liddell, Naeem Y. Shaikh, Kartik Sunagar, Alex Loukas, Michael J. Smout, Norelle L. Daly   +10 more
wiley   +1 more source

Comparisons of Protein and Peptide Complexity in Poneroid and Formicoid Ant Venoms [PDF]

, 2016
© 2016 American Chemical Society. Animal venom peptides are currently being developed as novel drugs and bioinsecticides. Because ants use venoms for defense and predation, venomous ants represent an untapped source of potential bioactive toxins.
Aili, SR, Dejean, A, Escoubas, P, Koh, JMS, Nicholson, GM, Orivel, J, Padula, MP, Touchard, A   +7 more
core   +2 more sources

Biophysical characterization and antitumor activity of synthetic Pantinin peptides from scorpion's venom

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2018
Antimicrobial peptides have been extensively described as bioactive agents, mainly considering their selective toxicity towards bacteria but not to healthy mammalian cells. In past years, this class of compounds has been classified as an attractive and novel family of anticancer agents.
Crusca, Edson, Basso, Luis Guilherme Mansor, Altei, Wanessa Fernanda, Marchetto, Reinaldo   +3 more
openaire   +3 more sources