Results 61 to 70 of about 7,379 (244)

ScorpDb: A Novel Open-Access Database for Integrative Scorpion Toxinology

Toxins
Scorpion stings are a significant public health concern globally, particularly in tropical and subtropical regions. Scorpion venoms contain a diverse array of bioactive peptides, and different scorpion species around the world typically exhibit varying ...
Masoumeh Baradaran, Fatemeh Salabi, Masoud Mahdavinia, Elaheh Mohammadi, Babak Vazirianzadeh, Ignazio Avella, Seyed Mahdi Kazemi, Tim Lüddecke   +7 more
doaj   +1 more source

Characterisation of three alpha-helical antimicrobial peptides from the venom of Scorpio maurus palmatus. [PDF]

, 2016
Scorpion venoms provide a rich source of anti-microbial peptides. Here we characterise three from the venom of Scorpion maurus palmatus. Smp13 is biologically inactive, despite sharing homology with other antimicrobial peptides, probably because it lacks
Abdel-Rahman, Andrews, Bahar, Baumann, Bobone, Calvete, Corzo, Dai, Dempsey, Gajski, Galanth, Glukhov, Hancock, Harrison, Hilliard, Holak, Huang, Jenssen, Jiang, Kaduk, Keith Miller, Kobayashi, Livermore, Ludtke, Matsuzaki, Melo, Moerman, Mohamed A. Abdel-Rahman, Mohamed M. Tawfik, Nelson, Nomura, Nomura, Park, Park, Patrick L. Harrison, Peter N. Strong, Powers, Rodríguez, Rodríguez, Shai, Shin, Sreerama, Teixeira, Torres-Larios, Urban, Whitmore, Yamaguchi, Yeaman, Yonezawa, Zasloff, Zasloff, Zeng, Zhang   +52 more
core   +1 more source

Pond frog as a predator of hornet workers: High tolerance to venomous stings

Ecosphere, Volume 16, Issue 12, December 2025.
Abstract Some animals use stingers to repel attackers, and some predators have evolved tolerance to such stings, enabling them to consume venomous prey. For example, social wasps, such as hornets, use modified ovipositors as venomous stingers to inject venom, which can cause intense pain in humans.
Shinji Sugiura
wiley   +1 more source

Scorpion venomics: a 2019 overview

Expert Review of Proteomics, 2019
Introduction: A few scorpions are dangerous to humans. Their medical relevance was the initial driving force for venom research. By classical biochemistry and molecular cloning, several venom peptides and their coding transcripts were characterized, mainly those related to toxins.
Jimena I, Cid-Uribe, José Ignacio, Veytia-Bucheli, Teresa, Romero-Gutierrez, Ernesto, Ortiz, Lourival D, Possani   +4 more
openaire   +2 more sources

Evolution: Fangtastic Venoms Underpin Parasitic Mimicry [PDF]

, 2017
Venomous teeth are rare in fishes, which typically utilise spines for defence. A new study reveals the evolutionary origins of fangs and venom in the Nemophini blennies and shows that, in contrast to snakes and lizards, the fangs pre-date the ...
Taylor, Martin I.
core   +1 more source

A Cell‐Penetrating Scorpion Venom Peptide Disrupts the HSP90β‐PPARα Interaction to Ameliorate Metabolic Dysfunction‐Associated Steatotic Liver Disease

iMetaMed, Volume 1, Issue 2, December 2025.
In MASLD, increased HSP90β interacts with PPARα, thereby inhibiting PPARα activation via the inhibition of its nuclear translocation. BmK Tx‐2, a cell‐penetrating peptide from Buthus martensii Karsch scorpion venom, enters hepatocytes via macropinocytosis and escapes endosomes to bind HSP90β.
Erjin Xu, Wuguang Lu, Yonggen Chen, Ming Sang, Jiao Chen, Xueting Cai, Wenhao Xu, Yuxin Zhang, Zhiheng Wang, Feng Zhang, Peng Cao   +10 more
wiley   +1 more source

Intervertebral Disc Proteoglycans: Multifunctional Tissue Stabilizing and Instructional Cell Regulatory Proteins That Control Tissue Homeostasis

JOR SPINE, Volume 8, Issue 4, December 2025.
Matrix and cell‐associated proteoglycans are important tissue‐stabilizing, weight‐bearing, and tension‐resisting proteins in the intervertebral disc. Their glycosaminoglycan components have growth factor binding and cell‐instructive properties that allow cells to regulate tissue composition and function.
James Melrose
wiley   +1 more source

Comparisons of Protein and Peptide Complexity in Poneroid and Formicoid Ant Venoms [PDF]

, 2016
© 2016 American Chemical Society. Animal venom peptides are currently being developed as novel drugs and bioinsecticides. Because ants use venoms for defense and predation, venomous ants represent an untapped source of potential bioactive toxins.
Aili, SR, Dejean, A, Escoubas, P, Koh, JMS, Nicholson, GM, Orivel, J, Padula, MP, Touchard, A   +7 more
core   +2 more sources

Gene and Genome Duplication in Spiders

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 344, Issue 7, Page 379-393, November 2025.
In chelicerates whole genome duplications (WGDs) were identified in distinct groups. While there is evidence that Xiphosurans/horseshoe crabs had three rounds of WGD and arachnopulmonates (e.g. spiders and scorpions) had one WGD, in many other arachnid groups no WGD was identified.
Chetan Munegowda, Matthias Pechmann, Nikola‐Michael Prpic‐Schäper, Natascha Turetzek   +3 more
wiley   +1 more source

Venomics of the scorpion Tityus ocelote (Scorpiones, Buthidae): Understanding venom evolution in the subgenus Archaeotityus

International Journal of Peptide Research and Therapeutics, 2022
AbstractThe subgenusTityus (Archaeotityus)includes small variegated species considered until recently, a basal group withinTityus, one of the most diverse and medically relevant genera of scorpions in the New World.Archaeotityusspecies are distributed in the humid forests of Lower Central America and the Choco, Guiana Shield, and Amazon regions. Due to
Díaz Oreiro, Cecilia, Chang Castillo, Arturo, Lomonte, Bruno, Bonilla Murillo, Fabián, Víquez, Carlos, Alfaro Chinchilla, Adriana, Triana Ricón, Felipe, Sasa Marín, Mahmood   +7 more
openaire   +2 more sources