Scrapie - Open Access .click

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New Zealand Veterinary Journal, 1977
Abstract Extract It will probably never be known why New Zealand sheep up to 1952 remained free from the particular slow virus disease called scrapie. Scrapie has occurred for many years in European countries from which many of our earlier sheep breeds were imported.
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Scrapie Agent and Neurones

Nature, 1972
THE nature of the scrapie agent1,2 is of considerable interest especially as to whether it is a virus in the strict sense, or some replicating agent devoid of nucleic acid3,4, or indeed whether scrapie disease represents a transmissible progressive biochemical transformation of cellular membranes5,6.
H K, Narang, B, Shenton, P P, Giorgi, E J, Field +3 more
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The nature of the scrapie agent

Medical Hypotheses, 1986
There now seems little doubt that the infective agent of scrapie cannot be accommodated within current concepts of virology/molecular biology. It is proposed: that the basic infective entity is a nucleic acid fragment (oligonucleotide) of some 40 bp coupled with specific (but host encoded) protein totalling approximately 10(5) daltons, a significant ...
D.H. Adams, null M.R.C. External Staff
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Novel proteinaceous infectious particles cause scrapie.

Science, 1982
S. Prusiner
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SCRAPIE