Results 81 to 90 of about 26,346 (266)
Scrapie is an infectious neurodegenerative disease affecting the central nervous system of sheep and goats that belongs to transmissible spongiform encephalopathies.
Nešić Slađan +4 more
doaj +1 more source
Sex‐specific differential expression of the genes in the synaptic vesicle cycle pathway of the amygdala in response to stimuli. In the pathway network depiction, the edges connecting the nodes (genes) represent known molecular interactions. More intense red and blue hues indicate gene under‐expression and over‐expression in response to fasting relative
Sreelaya Bhamidi +5 more
wiley +1 more source
High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrP in vivo [PDF]
Rona Barron - ORCID: 0000-0003-4512-9177 https://orcid.org/0000-0003-4512-9177Diagnosis of transmissible spongiform encephalopathy (TSE) disease in humans and ruminants relies on the detection in post-mortem brain tissue of the protease-resistant form of
Barron, R. M. +6 more
core +1 more source
Knock‐in mice expressing PrP with a partial deletion of the C‐terminal signal sequence (KIBVPrP248) showed reduced PrPC expression and resistance to prion infection. The underlying mechanism is that the mutant PrP is aberrantly retained in the endoplasmic reticulum and eventually undergoes proteasomal degradation.
Miryeong Yoo +12 more
wiley +1 more source
Classic Scrapie in Sheep with the ARR/ARR Prion Genotype in Germany and France
In the past, natural scrapie and bovine spongiform encephalopathy (BSE) infections have essentially not been diagnosed in sheep homozygous for the A136R154R171 haplotype of the prion protein.
Martin H. Groschup +12 more
doaj +1 more source
Lambs with scrapie susceptible genotypes have higher postnatal survival. [PDF]
BACKGROUND: Prion protein (PrP) alleles associated with scrapie susceptibility persist in many sheep populations even with high frequencies despite centuries of selection against them.
Rami M Sawalha +3 more
doaj +1 more source
Worldwide attention has been given to scrapie, because bovine spongiform encephalopathy (BSE) could be experimentally transmitted to sheep. This ovine form of BSE was clinically identical to scrapie. In Japanese scrapie cases, a majority of the diseased sheep were from Suffolk, while 8 cases were from Corriedale.
T, Onodera, K, Saeki
openaire +2 more sources
Factors influencing Wisconsin deer hunter participation in voluntary CWD testing
Hunter participation in testing harvested white‐tailed deer for chronic wasting disease (CWD) is a critical wildlife disease surveillance strategy. We present the results of a binary logistic model to quantify the effects of CWD status of the county of harvest, perceptions of CWD risk, trust in information provided by the management agency, and belief ...
Ben Beardmore +3 more
wiley +1 more source
Scrapie is a fatal neurodegenerative disease of sheep and goats belonging to the group of Transmissible Spongiform Encephalopathy or prion diseases. The EU has adopted mandatory measures for scrapie surveillance to safeguard public and animal health ...
Henrik Zetterberg +8 more
doaj +1 more source
The Molecular Pathology of Prion Diseases [PDF]
Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen +2 more
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