Results 61 to 70 of about 12,794 (224)
PLoS ONE, 2020 Scrapie, a prion disease of sheep, is highly resistant to conventional deactivation. Numerous methods to deactivate scrapie have been tested in laboratory animal models, and adequate autoclave treatment can reduce or remove the infectivity of some ...
Eric D Cassmann +2 more
doaj +1 more source
Anti-prion drug mPPIg5 inhibits PrP(C) conversion to PrP(Sc). [PDF]
, 2013 Prion diseases, also known as transmissible spongiform encephalopathies, are a group of fatal neurodegenerative diseases that include scrapie in sheep, bovine spongiform encephalopathy (BSE) in cattle and Creutzfeldt-Jakob disease (CJD) in humans.
Jeremy C. Simpson (29225) +31 more
core +1 more source
Classical and Atypical Scrapie in Sheep and Goats
, 2023 Scrapie is a naturally occurring transmissible spongiform encephalopathy (TSE) in sheep, goats and moufflons almost worldwide and is known for about 270 years.
Fast, Christine, Groschup, Martin H.
core +1 more source
Possible alignment of the EU BSE surveillance with the new WOAH provisions
EFSA Journal, Volume 24, Issue 4, April 2026.Abstract The European Commission requested the assessment of the capacity of the surveillance provisions of the World Organization for Animal Health (WOAH) to detect bovine spongiform encephalopathy (BSE) cases (C‐, H‐ and L‐type) in the European Union (EU) and to propose if any current EU surveillance provisions should be kept.
EFSA Panel on Animal Health and Welfare (AHAW) +25 more
wiley +1 more source
Prion diseases are efficiently transmitted by blood transfusion in sheep [PDF]
, 2008 The emergence of variant Creutzfeld-Jakob disease, following on from the bovine spongiform encephalopathy (BSE) epidemic, led to concerns about the potential risk of iatrogenic transmission of disease by blood transfusion and the introduction of costly ...
Foster, J. +8 more
core +1 more source
Classic Scrapie in Sheep with the ARR/ARR Prion Genotype in Germany and France
Emerging Infectious Diseases, 2007 In the past, natural scrapie and bovine spongiform encephalopathy (BSE) infections have essentially not been diagnosed in sheep homozygous for the A136R154R171 haplotype of the prion protein.
Martin H. Groschup +12 more
doaj +1 more source
Lambs with scrapie susceptible genotypes have higher postnatal survival. [PDF]
PLoS ONE, 2007 BACKGROUND: Prion protein (PrP) alleles associated with scrapie susceptibility persist in many sheep populations even with high frequencies despite centuries of selection against them.
Rami M Sawalha +3 more
doaj +1 more source
Scrapie-Associated Tubulofilamentous Particles in Scrapie Hamsters
Intervirology, 1992 Examination of thin sections from the cerebral cortex of scrapie-infected hamster brains revealed characteristic circular 26-30 nm diameter tubulofilamentous particles, identical to those previously described in both experimentally induced scrapie in mice, hamsters and natural scrapie of sheep, bovine spongiform encephalopathy and human Creutzfeldt ...
openaire +2 more sources
Journal of Animal Breeding and Genetics, Volume 143, Issue 1, Page 50-67, January 2026.ABSTRACT Genetic diversity is essential for the sustainability and adaptability of populations, and is thus a central pillar of the agro‐ecological transition. However, within a population, it is inevitable that some amount of genetic variability is lost, and efforts must be made to limit this as much as possible.
Alicia Jacques +2 more
wiley +1 more source