BackgroundMost previous analyses of scrapie outbreaks have focused on flocks run by research institutes, which may not reflect the field situation. Within this study, we attempt to rectify this deficit by describing the epidemiological characteristics of
K Marie McIntyre +4 more
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BACKGROUND AND OBJECTIVES: Transmissible spongiform encephalopathies (TSEs) including sheep scrapie are characterized by the conversion of a normal, cellular prion protein (PrPc) to an abnormal protease-resistant form (PrPSc). Like human peripheral blood,
LM Herrmann +6 more
doaj
Camel Prion Disease, Tataouine, Tunisia, 2019-2021. [PDF]
Amara A +21 more
europepmc +1 more source
Preclinical serum alterations and tissue changes in protein and gene expression of early cerebrospinal fluid-validated biomarkers in scrapie. [PDF]
Pérez-Lázaro S +4 more
europepmc +1 more source
Endogenous Ecotropic Murine Leukemia Virus Promotes Prion Pathogenesis in Senescence-accelerated Mice. [PDF]
Choi MW +7 more
europepmc +1 more source
Practical Real-Time Quaking-Induced Conversion for Detecting Classical Bovine Spongiform Encephalopathy and Classical and Atypical Scrapie Prions. [PDF]
Suzuki A +8 more
europepmc +1 more source
Incomplete protection of the K<sub>222</sub> polymorphism of the prion protein gene after intracerebral exposure to caprine BSE in goats: preliminary follow-up in S<sub>127</sub> carriers. [PDF]
Sola D +12 more
europepmc +1 more source
Therapeutic strategies in prion disease: current evidence, translational challenges, and emerging directions. [PDF]
Zhu Y, Bradford BM, Mabbott NA.
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The sheep and goat disease scrapie adapted to hamsters was studied as a model for unconventionals low virus diseases which are rare, fatal, spongiform encephalopathies of animals and man characterized by sometimes extreme long incubation periods, an apparent absence of any host immune reaction, and chemically and physically very resistant infectious ...
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