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ACAT1, Cav-1, and PrP expression in brains and skin fibroblasts from Sarda breed sheep with scrapie-resistant and scrapie-susceptible genotype. [PDF]
Scrapie is an infective ovine neurodegenerative disease; the only identified component of the infectious agent being an aberrant isoform (PrPSc) of the cellular prion protein (PrPC). So far, no means for ante-mortem diagnosis are available for Scrapie as
Alessandra Pani +9 more
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The Molecular Pathology of Prion Diseases [PDF]
, 2004 Prion diseases, or transmissible spongiform encephalopathies (TSEs), are a group of invariably fatal neurodegenerative disorders. Uniquely, they may present as sporadic, inherited, or infectious forms, all of which involve conversion of the normal ...
Herms, Jochen +2 more
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Factors influencing Wisconsin deer hunter participation in voluntary CWD testing
The Journal of Wildlife Management, Volume 89, Issue 7, September 2025.Hunter participation in testing harvested white‐tailed deer for chronic wasting disease (CWD) is a critical wildlife disease surveillance strategy. We present the results of a binary logistic model to quantify the effects of CWD status of the county of harvest, perceptions of CWD risk, trust in information provided by the management agency, and belief ...
Ben Beardmore +3 more
wiley +1 more source
High titers of transmissible spongiform encephalopathy infectivity associated with extremely low levels of PrP in vivo [PDF]
, 2007 Rona Barron - ORCID: 0000-0003-4512-9177 https://orcid.org/0000-0003-4512-9177Diagnosis of transmissible spongiform encephalopathy (TSE) disease in humans and ruminants relies on the detection in post-mortem brain tissue of the protease-resistant form of
Barron, R. M. +6 more
core +1 more source
Wildlife Biology, Volume 2025, Issue 5, September 2025.Chronic wasting disease (CWD) is well known among cervids in North America. Nevertheless, management faced different types and degrees of uncertainty when CWD was first detected in reindeer Rangifer tarandus in Nordfjella, Norway in 2016. We present a timeline of the efforts to control CWD, and identify how the process, measurement, environmental, and ...
Atle Mysterud +3 more
wiley +1 more source
Animal Industry News, 2009, Vol. 10, no. 1 [PDF]
, 2009 Newsletter produced by Department of Agriculture and Land Stewardship about the animal industry in ...
core
Global stability for the prion equation with general incidence [PDF]
, 2015 We consider the so-called prion equation with the general incidence term introduced in [Greer et al., 2007], and we investigate the stability of the steady states. The method is based on the reduction technique introduced in [Gabriel, 2012]. The argument
Gabriel, Pierre
core +4 more sources
Evidence of effective scrapie transmission via colostrum and milk in sheep
BMC Veterinary Research, 2013 BackgroundEvidence for scrapie transmission from VRQ/VRQ ewes to lambs via milk was first reported in 2008 but in that study there were concerns that lateral transmission may have contributed to the high transmission rate observed since five control ...
T. Konold +9 more
semanticscholar +1 more source
Advanced Biology, Volume 9, Issue 8, August 2025.Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi +4 more
wiley +1 more source
BMC Veterinary Research, 2020 Background Classical scrapie susceptibility in sheep has been linked to three polymorphisms at codon 136, 154, and 171 in the prion protein gene (PRNP) whereas atypical scrapie susceptibility is related to polymorphisms at codon 141.
Eden Yitna Teferedegn +2 more
doaj +1 more source