Results 111 to 120 of about 12,794 (224)

Scrapie a “gene”? [PDF]

Nature, 1982
openaire   +2 more sources

Effect of enzymatic deimination on the conformation of recombinant prion protein

, 2009
Deimination is the post-translational conversion of arginine residues to citrulline. It has been implicated as a causative factor in autoimmune diseases such as multiple sclerosis and rheumatoid arthritis and more recently, as a marker of ...
Oxley, David, Meersman, Filip, Webster, Judith, Young, Duncan S., Dear, Denise V., Bronstein, Igor, Gill, Andy   +6 more
core  

Inspecção do sistema nervoso central em pequenos ruminantes

Millenium, 2016
O Scrapie é uma doença neurodegenerativa fatal que afecta ovinos e caprinos e é a forma mais comum das Encefalopatias Espongiformes Transmissíveis (EET's), que incluem a doença de Creutzfeldt – Jakob (CJD), em humanos, e a Encefalopatia Espongiforme ...
Helena Vala, João Mesquita, Fernando Esteves   +2 more
doaj  

Exploring the mechanisms involved in prion degradation and spreading from cell-to-cell in neuronal cell models

, 2011
Transmissible spongiform encephalopathies (TSE), also known as prion diseases, are fatal neurodegenerative disorders present both in human and animals with different aetiology as they can occur genetically, spontaneously or by infection (Prusiner 1998 ...
Marzo, Ludovica
core  

Preclinical serum alterations and tissue changes in protein and gene expression of early cerebrospinal fluid-validated biomarkers in scrapie. [PDF]

Vet Res
Pérez-Lázaro S, Barrio T, Sevilla E, Bolea R, Badiola JJ.   +4 more
europepmc   +1 more source

Eradicating scrapie

Epidemiology and Infection, 2009
openaire   +2 more sources

Practical Real-Time Quaking-Induced Conversion for Detecting Classical Bovine Spongiform Encephalopathy and Classical and Atypical Scrapie Prions. [PDF]

Pathogens
Suzuki A, Sawada K, Nakashima T, Sato T, Miyazawa K, Matsuura Y, Ikeda K, Iwamaru Y, Horiuchi M.   +8 more
europepmc   +1 more source

Brain bioenergetics in murine models of scrapie using in vivo 31P magnetic resonance spectroscopy

, 1999
The bioenergetic status of the brain in scrapie mouse models was investigated during the late, clinical phase of the disease, by in vivo phosphorus magnetic resonance spectroscopy (MRS).
Williams, S.C.R., Bell, J.D., Hope, J., Chung, Y.L.   +3 more
core  

Incomplete protection of the K₂₂₂ polymorphism of the prion protein gene after intracerebral exposure to caprine BSE in goats: preliminary follow-up in S₁₂₇ carriers. [PDF]

Vet Res
Sola D, Pitarch JL, Marín B, Raksa HC, Otero A, Barillet F, Bouvier F, Bolea R, Bossers A, Andreoletti O, Langeveld J, Badiola JJ, Acín C.   +12 more
europepmc   +1 more source

The prion protein gene:a role in mouse embryogenesis?

, 1992
The neural membrane glycoprotein PrP (prion protein) has a key role in the development of scrapie and related neurodegenerative diseases. During pathogenesis, PrP accumulates in and around cells of the brain from which it can be isolated in a disease ...
McBride, P, West, J D, Kaufman, M H, Hope, J; id_orcid, Thomson, V, Manson, J   +5 more
core