Results 251 to 260 of about 81,661 (282)

Commentary: Analysis of head and neck cancer scRNA-seq data identified PRDM6 promotes tumor progression by modulating immune gene expression. [PDF]

Front Immunol
Li M, Zhou Y, Cai M.
europepmc   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

scRNA-seq deciphers molecular mechanisms of endocrine disruptor 4-nonylphenol impairing spermatogenesis in mice. [PDF]

Cell Biol Toxicol
Zhao X, Tian Y, Zhou D, Tang X, Zhou X, Wang X, He Y, Yu P, Huang J, Tan Y, Duan P.   +10 more
europepmc   +1 more source

Mechanical Strain‐Programmed SDC1+ Sheath Fibroblasts Trigger CXCR4hi Neutrophil‐Mediated Enthesitis in Ankylosing Spondylitis

Advanced Science, EarlyView.
In ankylosing spondylitis (AS), mechanical strain‐programmed SDC1+ sheath fibroblasts secrete CXCL5 to recruit neutrophils and promote the activation of CXCR4hi neutrophils, thereby exacerbating enthesitis by promoting neutrophil extracellular traps (NETs) formation. SOX5 controls the generation of SDC1+ sheath fibroblasts via super‐enhancers.
Jiajie Lin, Zepeng Su, Yipeng Zeng, Yi Zhou, Chenying Zeng, Weihao Zhang, Qibo Li, Zipeng Xiao, Zibin Chen, Ziqian Liu, Yangfeng Lin, Guan Zheng, Wenhui Yu, Zhongyu Xie   +13 more
wiley   +1 more source

Comprehensive Analysis of scRNA-Seq and Bulk RNA-Seq Identified TIMP1 as a Prognostic Marker in Colorectal Cancer. [PDF]

Immune Netw
Luo QW, Shi YC, Jia WQ, Zhou XH, Yang ZR, Wang Y, Guan QL.   +6 more
europepmc   +1 more source

Identification of immune reconstitution and hematopoiesis restoration by scRNA-seq in bone marrow of multiple myeloma patients treated with high-dose melphalan following auto-HSCT. [PDF]

Cancer Biol Med
Li Q, Wang Y, Yuan H, Cai Q, Zhao L, Lin L, Gao S, Chen L, Zhang Z, Ma J, Liu S, Cao Z, Zhao H, Wang Y, Li S, Lv P, Zhang H, Wang G, Yang G, Zhang X, Wang Y.   +20 more
europepmc   +1 more source

Structure-guided integrative soft deep clustering analysis of scRNA-seq and scATAC-seq data. [PDF]

Front Microbiol
Xingzuo J, Chenyuan W, Jiaxi Y, Chengyuan W.   +3 more
europepmc   +1 more source

Deciphering lactate/lactylation networks in AML: integrated scRNA-seq and transcriptomics reveal functions and prognostic model. [PDF]

BMC Cancer
Chen X, Feng A, Guo H, Zeng J, Chen M.
europepmc   +1 more source

DropDAE: Denosing Autoencoder with Contrastive Learning for Addressing Dropout Events in scRNA-seq Data. [PDF]

Bioengineering (Basel)
Juan W, Ahn KW, Chen YG, Lin CW.
europepmc   +1 more source