Results 101 to 110 of about 5,354,916 (300)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Evidence for the stability of the West Antarctic Ice Sheet divide for 1.4 million years [PDF]

, 2016
Past fluctuations of the West Antarctic Ice Sheet (WAIS) are of fundamental interest because of the possibility of WAIS collapse in the future and a consequent rise in global sea level.
Sugden, David, Stuart, Finlay, Freeman, Stewart, Freeman, Stewart P.H.T., Woodward, John, Marrero, Shasta, Steig, Eric J., Stuart, Finlay M., Westoby, M. J., Westoby, Matt, Sugden, David E., Marrero, Shasta M., Freeman, Stewart P. H. T., Dunning, Stuart, Winter, Kate, Hein, Andrew, Westoby, Matthew J., Hein, Andrew S., Dunning, Stuart A., Steig, Eric, Steig, Eric.J., Hein, Andrew; id_orcid   +21 more
core   +1 more source

The impact of sea ice melt on the evolution of surface pCO2 in a polar ocean basin

Frontiers in Marine Science
The strong CO2 sink in Arctic Ocean plays a significant role in the global carbon budget. As a high-latitude oceanic ecosystem, the features of sea surface pCO2 and air-sea CO2 flux are significantly influenced by sea ice melt; however, our understanding
Wei Yang, Yu Zhao, Yingxu Wu, Zijie Chen, Xiang Gao, Hongmei Lin, Zhangxian Ouyang, Weijun Cai, Liqi Chen, Di Qi   +9 more
doaj   +1 more source

Microbial Loop Dynamics in Antarctic Sea-Ice [PDF]

, 2021
<p>Sea-ice is a predominant feature of polar oceans and exerts a unique influence on marine ecosystems. The annual circumpolar expansion of sea-ice around Antarctica provides a stable platform for the in situ colonisation and growth of a diverse assemblage of microbes that are integral to the energy base of the Southern Ocean. An active microbial
openaire   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Evaluating Landfast Sea Ice Ridging near UtqiaġVik Alaska Using TanDEM-X Interferometry [PDF]

, 2020
Seasonal landfast sea ice stretches along most Arctic coastlines and serves as a platform for community travel and subsistence, industry operations, and as a habitat for marine mammals.
Marbouti, Marjan,, Eriksson, Leif, Jones, Joshua M.,, Oleg Antropov, Demchev, Denis, Eriksson, Leif,, Marbouti, Marjan, Anders Berg, Demchev, Denis,, Dammann, Dyre Oliver,, Dammann, Dyre Oliver, Antropov, Oleg, Eriksson, Leif E.B., Denis Demchev, Leif E. B. Eriksson, Jones, Joshua, Marjan Marbouti, Joshua Jones, Jones, Joshua M., Berg, Anders,, Antropov, Oleg; id_orcid, Eriksson, Leif E. B., Berg, Anders, Dyre Oliver Dammann, Antropov, Oleg,   +24 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Sea-ice thickness, snow depth, freeboard, scattering layer thickness, and sea-ice type at sea ice station PS78/230-1

, 2012
Sea-ice thickness, snow depth, freeboard, scattering layer thickness, and sea-ice type at sea ice station PS78/267-
James A Maslanik (6979643), Maslanik, James A, Nicolaus, Marcel, Christian Katlein (6962774), Stefan Hendricks (6887366), Hendricks, Stefan, Katlein, Christian, Marcel Nicolaus (6887372)   +7 more
core   +1 more source

Frazil dynamics and precipitation in a water column with depth-dependent supercooling [PDF]

, 2005
When seawater becomes supercooled, collections of small ice crystals, known as frazil ice, form and grow. A model of frazil ice dynamics is presented that deals explicitly with the buoyant settling of frazil crystals onto an overlying surface.
Feltham, DL, Holland, PR, Holland, Paul R., Feltham, Daniel L.   +3 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source