Results 111 to 120 of about 5,134,596 (300)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

The Roles of Sea-Ice, Light and Sedimentation in Structuring Shallow Antarctic Benthic Communities.

PLoS ONE, 2017
On polar coasts, seasonal sea-ice duration strongly influences shallow marine environments by affecting environmental conditions, such as light, sedimentation, and physical disturbance.
Graeme F Clark, Jonathan S Stark, Anne S Palmer, Martin J Riddle, Emma L Johnston   +4 more
doaj   +1 more source

Sea-ice dynamics in the Weddell Sea in winter [PDF]

Annals of Glaciology, 1991
Observations of ice drift received from an array of ARGOS buoys drifting in the Weddell Sea in winter 1986 are described. Wind and current data are also available, permitting derivation of the complete momentum budget including the internal ice stress computed as residuum.
openaire   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

The last glaciation of Shetland : local ice cap or invasive ice sheet? [PDF]

, 2014
Issue ISBN: 978-82-92-39488-5 This work is supported by the Carnegie Trust for the Universities of ScotlandThe question of whether the Shetland Islands were covered by an ice cap or by an ice sheet during the last glacial cycle (40–10 ka) remains ...
Hall, A. M.
core   +2 more sources

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Intra‐population variation in the effects of sea ice reduction on an Arctic breeding bird

Ecosphere
The Arctic is warming four times faster than any other region on Earth, leading to a dramatic reduction in sea ice. Even though sea ice plays a key role in the ecology of many Arctic species, few studies have assessed the consequences of its ...
Hilde Dørum, Sébastien Descamps, Børge Moe, Bård‐Jørgen Bårdsen, Kjell Tore Hansen, Sveinn Are Hanssen, Christophe Sauser, Marika Marnela, Sebastian Gerland, Geir W. Gabrielsen   +9 more
doaj   +1 more source

Trimlines, blockfields and the vertical extent of the last ice sheet in southern Ireland [PDF]

, 2015
The research reported here was supported by UK NERC grant NER/B/S/2001/0919Trimlines separating glacially abraded lower slopes from blockfield-covered summits on Irish mountains have traditionally been interpreted as representing the upper limit of the ...
Stone, John O., John O. Stone, Ballantyne, Colin, Colin K. Ballantyne   +3 more
core   +1 more source