Results 71 to 80 of about 5,354,916 (300)

High-resolution regional sea-ice model based on the discrete element method with boundary conditions from a large-scale model for ice drift

Annals of Glaciology
Understanding sea-ice dynamics at the floe scale is crucial to comprehend polar climate systems. While continuum models are commonly used to simulate large-scale sea-ice dynamics, they have limitations in accurately representing sea-ice behaviour at ...
Andrei Tsarau, Wenjun Lu, Raed Lubbad, Sveinung Løset, Yuan Zhang   +4 more
doaj   +1 more source

Dynamics of Arctic sea ice discussed at workshop [PDF]

Eos, Transactions American Geophysical Union, 2000
Sea ice is an interesting geophysical material: it behaves as a large‐scale hardening plastic. Consider the impact of the sea‐ice covers mechanical behavior on the energy and momentum exchange within the complex atmosphere‐ice‐ocean system. Sea ice acts as an insulator between the relatively warm ocean water and the cold polar atmosphere. Sea ice cover
James Overland, Jinro Ukita
openaire   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Voronoi Dynamics Simulation of Development of Lamellar Microstructure in Sea Ice [PDF]

, 2008
Developments of sea ice polycrystals from the sea surface are simulated in two-dimensional approximation by combining numerical methods for crystal growth, salinity diffusion and flux of heat. An anisotropic growth of ice crystals from a number of nuclei
カワノ, ヨシキ, 大橋, 鉄也, 河野, 義樹, Kawano, Yoshiki   +3 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Evaluation of Operation IceBridge quick-look snow depth estimates on sea ice [PDF]

, 2015
We evaluate Operation IceBridge (OIB) ‘quick-look’ (QL) snow depth on sea ice retrievals using in situ measurements taken over immobile first-year ice (FYI) and multi-year ice (MYI) during March of 2014. Good agreement was found over undeformed FYI (-4.5
Joshua King, Richter-Menge, Jacqueline, Howell, Stephen, Kurtz, Nathan, Haas, Christian, Stephen Howell, Justin F. Beckers, Nathan Kurtz, Peter Toose, King, Joshua, Beckers, Justin, Chris Derksen, Nick Rutter, Christian Haas, Jacqueline Richter‐Menge, Toose, Peter, Rutter, Nick, Derksen, Chris   +17 more
core   +1 more source

Halogen-based reconstruction of Russian Arctic sea ice area from the Akademii Nauk ice core (Severnaya Zemlya) [PDF]

The Cryosphere, 2016
The role of sea ice in the Earth climate system is still under debate, although it is known to influence albedo, ocean circulation, and atmosphere–ocean heat and gas exchange.
A. Spolaor, T. Opel, J. R. McConnell, O. J. Maselli, G. Spreen, C. Varin, T. Kirchgeorg, D. Fritzsche, A. Saiz-Lopez, P. Vallelonga   +9 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Experiments on sea ice fracture toughness in the Bohai Sea

Shui kexue jinzhan, 2013
The fracture toughness of sea ice is an important parameter to analyze ice load on offshore structures,and also affects the sea ice dynamics,such as sea ice breakage,rafting and ridging,etc.In this study,sea ice samples were collected in the Liaodong Bay
JI Shunying, LIU Hongliang, XU Ning, MA Hongyan   +3 more
doaj   +1 more source

Pancake sea ice kinematics and dynamics using shipboard stereo video

Annals of Glaciology, 2020
In the marginal ice zone, surface waves drive motion of sea ice floes. The motion of floes relative to each other can cause periodic collisions, and drives the formation of pancake sea ice.
Madison Smith, Jim Thomson
doaj   +1 more source