Results 71 to 80 of about 878,327 (287)

Impact of rheology on probabilistic forecasts of sea ice trajectories: application for search and rescue operations in the Arctic [PDF]

open access: yes, 2018
We present a sensitivity analysis and discuss the probabilistic forecast capabilities of the novel sea ice model neXtSIM used in hindcast mode. The study pertains to the response of the model to the uncertainty on winds using probabilistic forecasts of ...
Bertino, Laurent   +4 more
core   +3 more sources

Pericytes change function depending on glioblastoma vicinity: emphasis on immune regulation

open access: yesMolecular Oncology, EarlyView.
Pericytes alter their transcriptome depending on their proximity to the tumor core. In the tumor core, pericytes display a more active state with higher communication strength but with lower immune activation potential and a shift toward extracellular matrix production.
Carolina Buizza   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Southern Ocean warming: Increase in basal melting and grounded ice loss [PDF]

open access: yes, 2013
We apply a global finite element sea ice/ice shelf/ocean model (FESOM) to the Antarctic marginal seas to analyze projections of ice shelf basal melting in a warmer climate.
Determann, Jürgen   +2 more
core  

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

An optical model for the microwave properties of sea ice [PDF]

open access: yes
The complex refractive index of sea ice is modeled and used to predict the microwave signatures of various sea ice types. Results are shown to correspond well with the observed values of the complex index inferred from dielectic constant and dielectric ...
Gloersen, P., Larabee, J. K.
core   +1 more source

Characterization of the thermophilic xylanase Fsa02490Xyn from the hyperthermophile Fervidibacter sacchari belonging to glycoside hydrolase family 10

open access: yesFEBS Open Bio, EarlyView.
Fervidibacter sacchari is a member of the bacterial phylum Armatimonadota, only a few of which have been cultivated. It is a hyperthermophilic polysaccharide degradation specialist. We show that a secreted enzyme, Fsa02490Xyn, is an endoxylanase belonging to glycoside hydrolase family 10.
Nicole Torosian   +10 more
wiley   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

open access: yesFEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang   +6 more
wiley   +1 more source

Effects of Sea Ice on Baltic Sea Eutrophication

open access: yesMarine Pollution Bulletin
This study investigates the influence of sea ice on eutrophication in the Baltic Sea ecosystem by comparing simulations from 1953 to 2017, with ice and without ice cover. We assessed the impact from ice cover by using eutrophication indicators defined by the Marine Strategy Framework Directive (MSFD), the Dia/Dino index and the newly proposed Trophic ...
Parn, Ove   +10 more
openaire   +3 more sources

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