Results 91 to 100 of about 5,354,706 (300)

Late Quaternary ice-ocean interactions in central West Greenland [PDF]

, 2011
A greater knowledge of the interactions between the Greenland Ice Sheet and climate is critical to understanding the possible impacts of future global warming, including ice sheet contribution to global sea-level rise and perturbations to ocean ...
MCCARTHY, DAVID,JOHN, McCarthy, David John   +1 more
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Barents Sea ice cover reflects Atlantic inflow [PDF]

, 2011
The recent Arctic winter sea-ice retreat is most pronounced in the Barents Sea. Using available observations of the Atlantic inflow to the Barents Sea and results from a regional ice-ocean model we assess the role of inflowing heat anomalies on sea-ice ...
Skagseth, Øystein, Årthun, Marius, Eldevik, Tor, Smedsrud, Lars Henrik   +3 more
core  

Evidence for the stability of the West Antarctic Ice Sheet divide for 1.4 million years [PDF]

, 2016
Past fluctuations of the West Antarctic Ice Sheet (WAIS) are of fundamental interest because of the possibility of WAIS collapse in the future and a consequent rise in global sea level.
Sugden, David, Stuart, Finlay, Freeman, Stewart, Freeman, Stewart P.H.T., Woodward, John, Marrero, Shasta, Steig, Eric J., Stuart, Finlay M., Westoby, M. J., Westoby, Matt, Sugden, David E., Marrero, Shasta M., Freeman, Stewart P. H. T., Dunning, Stuart, Winter, Kate, Hein, Andrew, Westoby, Matthew J., Hein, Andrew S., Dunning, Stuart A., Steig, Eric, Steig, Eric.J., Hein, Andrew; id_orcid   +21 more
core   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

The impact of sea ice melt on the evolution of surface pCO2 in a polar ocean basin

Frontiers in Marine Science
The strong CO2 sink in Arctic Ocean plays a significant role in the global carbon budget. As a high-latitude oceanic ecosystem, the features of sea surface pCO2 and air-sea CO2 flux are significantly influenced by sea ice melt; however, our understanding
Wei Yang, Yu Zhao, Yingxu Wu, Zijie Chen, Xiang Gao, Hongmei Lin, Zhangxian Ouyang, Weijun Cai, Liqi Chen, Di Qi   +9 more
doaj   +1 more source

Sea ice friction and Arctic sea ice dynamics

, 2010
A series of double-shear experiments were undertaken in the Environmental Test Basin at the Hamburgische Shiffbau-Versuchsanstalt (HSVA) in Hamburg. The aim of these experiments was to improve understanding of transient behaviour in sea ice friction. To this end we have fitted our experimental results to a rate- and state- dependent model of friction ...
Lishman, Ben, Sammonds, Peter, Feltham, Danny, Wilchinsky, Alex   +3 more
openaire   +1 more source

Spatiotemporal Variations in Sea Ice Albedo: A Study of the Dynamics of Sea Ice Albedo in the Sea of Okhotsk

Remote Sensing
This study utilizes a novel albedo retrieval framework combining radiative transfer modeling with scientific machine learning (RTM-SciML) to investigate sea ice dynamics in the Sea of Okhotsk. By validating albedo estimates derived from the MODIS sensor against in situ pyranometer measurements near the Hokkaido coast, we achieved a robust Pearson ...
Yingzhen Zhou, Wei Li, Nan Chen, Takenobu Toyota, Yongzhen Fan, Tomonori Tanikawa, Knut Stamnes   +6 more
openaire   +2 more sources

Evaluating Landfast Sea Ice Ridging near UtqiaġVik Alaska Using TanDEM-X Interferometry [PDF]

, 2020
Seasonal landfast sea ice stretches along most Arctic coastlines and serves as a platform for community travel and subsistence, industry operations, and as a habitat for marine mammals.
Marbouti, Marjan,, Eriksson, Leif, Jones, Joshua M.,, Oleg Antropov, Demchev, Denis, Eriksson, Leif,, Marbouti, Marjan, Anders Berg, Demchev, Denis,, Dammann, Dyre Oliver,, Dammann, Dyre Oliver, Antropov, Oleg, Eriksson, Leif E.B., Denis Demchev, Leif E. B. Eriksson, Jones, Joshua, Marjan Marbouti, Joshua Jones, Jones, Joshua M., Berg, Anders,, Antropov, Oleg; id_orcid, Eriksson, Leif E. B., Berg, Anders, Dyre Oliver Dammann, Antropov, Oleg,   +24 more
core   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source