Results 71 to 80 of about 4,079,930 (328)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Spatial and Temporal Variations in the Extent and Thickness of Arctic Landfast Ice
Analyses of landfast ice in Arctic coastal areas provide a comprehensive understanding of the variations in Arctic sea ice and generate data for studies on the utilization of the Arctic passages.
Zixuan Li +7 more
doaj +1 more source
Influence of Sea Surface Temperature in the Tropics on the Antarctic Sea Ice during Global Warming
Sea ice extent in the Antarctica, unlike in the Arctic, did not show a decrease until 2016 under observed global warming. The aim of the study is to explain this climatic phenomenon based on the idea of joint dynamics of the Southern Ocean oceanic ...
Genrikh Alekseev +2 more
doaj +1 more source
The extent of Arctic sea ice dropped to 3.41 million square kilometers on 16 September, 760,000 square kilometers below the minimum ice extent in 2007, which had been the low mark since the satellite record began in 1979, the National Snow and Ice Data Center (NSIDC) announced.
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Ice floe distribution in the Sea of Okhotsk in the period when sea‐ice extent is advancing [PDF]
Ice floe distribution in the Sea of Okhotsk during a cold‐air outbreak was investigated by analyzing several thousand of sea‐ice images obtained by the aircraft observation on 18 February in 2000. The effective floe size became small (from 10 m to 2 m) within the marginal ice zone (MIZ). The scaling properties of floe distribution are demonstrated by a
Jun Inoue +2 more
openaire +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Record low Antarctic sea ice coverage indicates a new sea ice state
In February 2023, Antarctic sea ice set a record minimum; there have now been three record-breaking low sea ice summers in seven years. Following the summer minimum, circumpolar Antarctic sea ice coverage remained exceptionally low during the autumn and ...
A. Purich, E. Doddridge
semanticscholar +1 more source

