Results 91 to 100 of about 3,764 (237)

Pharmacokinetics of a Novel Piperaquine Dispersible Granules Formulation Under Fasting and Various Fed Conditions Versus Piperaquine Tablets When Fasted in Healthy Tanzanian Adults: A Randomized, Phase I Study

Clinical and Translational Science, Volume 18, Issue 2, February 2025.
ABSTRACT Piperaquine tetraphosphate (PQP), a long‐acting antimalarial, is being considered in a combination for chemoprevention. Dihydroartemisinin‐piperaquine tablets (hard and dispersible) approved for the treatment of acute uncomplicated malaria should be administered in a fasted state, as PQP bioavailability increases with food.
Florence A. Milando, Said Jongo, Salim Abdulla, Gloria Nyaulingo, Anneth‐Mwasi Tumbo, Sarah Mswata, Juliether Tiago, Beatus S. Bongole, Ashura Mirambo, Kamaka Kassimu, Hussein Mbarak, Mohammed A. Rashid, Ali Hamad, Michael Mihayo, Tunu Ndanzi, Omary Zuberi, Naima Saadia, Mariam Somboka, Mariam Yamba‐Yamba, Theresia Ngonyani, Amina Nditi, Margaret Msuya, Bakari Mwalimu, Hajirani M. Msuya, Khamis Awadh, Ali Ali, Anne Claire Marrast, Denis Gossen, Alice Neequaye, Myriam El‐Gaaloul, Hanu Ramachandruni, Isabelle Borghini‐Fuhrer   +31 more
wiley   +1 more source

Evaluation of direct and indirect effects of seasonal malaria chemoprevention in Mali [PDF]

Scientific Reports, 2018
AbstractRandomized controlled trials have established that seasonal malaria chemoprevention (SMC) in children is a promising strategy to reduce malaria transmission in Sahelian West Africa. This strategy was recently introduced in a dozen countries, and about 12 million children received SMC in 2016. However, evidence on SMC effectiveness under routine
openaire   +3 more sources

Effect of routine seasonal malaria chemoprevention on malaria trends in children under 5 years in Dangassa, Mali [PDF]

Malaria Journal, 2020
Abstract Background Seasonal malaria chemoprevention (SMC) is a new strategy to prevent malaria in children under 5 years old. It has been recommended by the World Health Organization since 2012 in malaria-endemic areas with seasonal transmission. This study aimed to assess the changes in malaria indicators through two consecutive years of SMC routine ...
Drissa Konaté, Sory I. Diawara, Mahamoudou Touré, Seidina A. S. Diakité, Agnès Guindo, Karim Traoré, Ayouba Diarra, Bourama Keita, Sibe Thiam, Moussa Keita, Ibrahim Sissoko, Nafomon Sogoba, Sékou F. Traoré, Donald J. Krogtad, Seydou Doumbia, Mahamadou Diakité   +15 more
openaire   +3 more sources

Malaria intervention scale-up in Africa : effectiveness predictions for health programme planning tools, based on dynamic transmission modelling [PDF]

, 2016
Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-based.
Briët, Olivier J. T., Cibulskis, Richard, Hamilton, Matthew, Korenromp, Eline, Lauer, Jeremy, Mahiané, Guy, Pretorius, Carel, Smith, Thomas A.   +7 more
core   +6 more sources

Making the most of malaria chemoprevention

Malaria Journal
Against a backdrop of stalled progress in malaria control, it is surprising that the various forms of malaria chemoprevention are not more widely used. The World Health Organization (WHO) has recommended several malaria chemoprevention strategies, some ...
Jasper Littmann, Dorothy Achu, Miriam K. Laufer, Corine Karema, David Schellenberg   +4 more
doaj   +1 more source

A LC‐MS/MS Assay for Quantification of Amodiaquine and Desethylamodiaquine in Dried Blood Spots on Filter Paper

International Journal of Analytical Chemistry, Volume 2025, Issue 1, 2025.
Artesunate–amodiaquine (ARS–AQ) is a first‐line antimalarial treatment recommended by the World Health Organization. AQ is the long acting partner drug in this combination, and therapeutic success is correlated with the terminal exposure to AQ. Dried blood spot (DBS) sampling for AQ is a convenient and minimally invasive technique, especially suitable ...
Natpapat Kaewkhao, Joel Tarning, Daniel Blessborn, Daipayan Roy   +3 more
wiley   +1 more source

The use of video job-aids to improve the quality of seasonal malaria chemoprevention delivery

PLOS Digital Health, 2022
Mobile phones are increasingly used in community health programmes, but the use of video job-aids that can be displayed on smart phones has not been widely exploited. We investigated the use of video job-aids to support the delivery of seasonal malaria chemoprevention (SMC) in countries in West and Central Africa. The study was prompted by the need for
Susana Scott, Bienvenu Salim Camara, Michael Hill, Eugène Kaman Lama, Lansana Barry, Aurore Ogouyemi-Hounto, William Houndjo, Gauthier Tougri, Nombre Yacouba, Dorothy Achu, Marcellin Ateba, Mahamat Saleh Issakha Diar, Keziah L. Malm, Kofi Adomako, Paolo Djata, Wica Da Silva, Idrissa Cissé, Vincent Sanogo, Hadiza Jackou, Nnenna Ogbulafor, Bala M. Adu, Jamilu Nikau, Seynabou Gaye, Alioune Badara Gueye, Balla Kandeh, Olimatou Kolley, Tinah Atcha-Oubou, Tchassama Tchadjobo, Kovana Marcel Loua, Andre-Marie Tchouatieu, Ibrahima Mbaye, Maria-Angeles Lima-Parra, Abena Poku-Awuku, Jean Louis Ndiaye, Corinne Merle, Liz Thomas, Paul Milligan   +36 more
openaire   +4 more sources

Population impact of malaria control interventions in the health district of Kati, Mali.

PLoS ONE
BackgroundWHO and its partners have adopted alternative control interventions since the failure to eradicate malaria worldwide in the 1960s and 1970s.
Abdoulaye Katile, Issaka Sagara, Mady Cissoko, Cédric Stéphane Bationo, Mathias Dolo, Pascal Dembélé, Bourama Kamate, Ismaila Simaga, Mahamadou Soumana Sissoko, Jordi Landier, Jean Gaudart   +10 more
doaj   +1 more source

Plasmodium falciparum drug resistance in Angola [PDF]

, 2016
Facing chloroquine drug resistance, Angola promptly adopted artemisinin-based combination therapy as the first-line to treat malaria. Currently, the country aims to consolidate malaria control, while preparing for the elimination of the disease, along ...
Brito, Miguel, Fançony, Cláudia, Gil, Jose Pedro   +2 more
core   +2 more sources

Determinants of Insecticide‐Treated Net Utilization for Malaria Prevention Among Under‐Five Children in The Gambia: Evidence From National Survey

Journal of Tropical Medicine, Volume 2025, Issue 1, 2025.
Background: Malaria is one of the deadliest mosquito‐borne diseases. Despite the demonstrated benefits of insecticide‐treated nets (ITNs) usage in children under 5 years of age, nonuse is linked to higher mortality and morbidity rates. This study examined how child‐, maternal‐, household‐, and community‐level determinants influence ITN utilization ...
Amadou Barrow, Bakary Kinteh, Mansour Badjie, Amadou Kongira, Ayodeji Matthew Adebayo, Rex A. Kuye, Edrisa Sanyang, Priya Gusain   +7 more
wiley   +1 more source