Results 91 to 100 of about 8,311 (256)

Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS,S/AS01_Evaccine, seasonal malaria chemoprevention and the combination of vaccination and chemoprevention

BMJ Open, 2020
IntroductionSeasonal malaria chemoprevention (SMC), with sulphadoxine–pyrimethamine plus amodiaquine (SP+AQ) is effective but does not provide complete protection against clinical malaria. The RTS,S/AS01Emalaria vaccine provides a high level of protection shortly after vaccination, but this wanes rapidly.
Ismaila Thera, Irene Kuepfer, Daniel Chandramohan, Alassane Dicko, Issaka Zongo, Issaka Sagara, Matthew Cairns, Modibo Diarra, Amadou Tapily, Djibrilla Issiaka, Koualy Sanogo, Almahamoudou Mahamar, Frederic Sompougdou, Serge Yerbanga, Paul Milligan, Halidou Tinto, Opokua Ofori-Anyinam, Jean-Bosco Ouedraogo, B Greenwood   +18 more
openaire   +3 more sources

Women's Experiences and Views about Costs of Seeking Malaria Chemoprevention and other Antenatal Services: A Qualitative Study from two Districts in Rural Tanzania. [PDF]

, 2010
The Tanzanian government recommends women who attend antenatal care (ANC) clinics to accept receiving intermittent preventive treatment against malaria during pregnancy (IPTp) and vouchers for insecticide-treated nets (ITNs) at subsidized prices.
A Hardon, AGH Thompson, AK Hussein, AK Mbonye, B Greenwood, B Greenwood, C Boller, C Goodman, C Quijada, Department for International Development (DFID), E Torell, E Worrall, G Mubyazi, G Mubyazi, G Munishi, GB Overbosch, GM Mubyazi, GM Mubyazi, GM Mubyazi, GM Mubyazi, GM Mubyazi, Godfrey M Mubyazi, H Birungi, Ib C Bygbjerg, J Hill, J Sachs, Jens Byskov, K Hanson, K Wyss, Kristian S Hansen, M Mamdani, M Rao, Malaria Consortium, Mapping Malaria Risk in Africa (MARA), Ministry of Health, Ministry of Health, Ministry of Health-Tanzania, MJ Ribera, Pascal Magnussen, Paul Bloch, PL Olliaro, RP Shaw, T Ensor, T Mathole, TANHERF, W Newbrander, WHO, WHO, WHO, Øystein E Olsen   +49 more
core   +4 more sources

Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger

Malaria Journal, 2021
Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha, Rafiou Adamou, Maman Laminou Ibrahim, Mariama Abdoulaye Louis Padounou, Abdoulaye Diallo, David Courtin, Jean Testa, Jean Louis Abdourahim Ndiaye   +7 more
doaj   +1 more source

Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]

The Journal of Infectious Diseases, 2019
Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Oumar, Attaher, Irfan, Zaidi, Jennifer L, Kwan, Djibrilla, Issiaka, Mamoudou B, Samassekou, Kadidia B, Cisse, Barou, Coulibaly, Sekouba, Keita, Sibiri, Sissoko, Tiangoua, Traore, Kalifa, Diarra, Bacary S, Diarra, Adama, Dembele, Moussa B, Kanoute, Almahamoudou, Mahamar, Amadou, Barry, Michal, Fried, Alassane, Dicko, Patrick E, Duffy   +18 more
openaire   +2 more sources

Sub-national tailoring of seasonal malaria chemoprevention in Mali based on malaria surveillance and rainfall data

Parasites & Vectors, 2022
Abstract Background In malaria endemic countries, seasonal malaria chemoprevention (SMC) interventions are performed during the high malaria transmission in accordance with epidemiological surveillance data. In this study we propose a predictive approach for tailoring the timing and number of cycles of SMC in all health ...
Cissoko, Mady, Sagara, Issaka, Landier, Jordi, Guindo, Abdoulaye, Sanogo, Vincent, Coulibaly, Oumou, Dembélé, Pascal, Dieng, Sokhna, Bationo, Cedric, Diarra, Issa, Magassa, Mahamadou, Berthé, Ibrahima, Katilé, Abdoulaye, Traoré, Diahara, Dessay, Nadine, Gaudart, Jean   +15 more
openaire   +4 more sources

A proposed method of grading malaria chemoprevention efficacy [PDF]

, 2023
The efficacy and effectiveness of antimalarial drugs are threatened by increasing levels of resistance and therefore require continuous monitoring. Chemoprevention is increasingly deployed as a malaria control measure, but there are no generally accepted
Bonnington, C, Nosten, Fh, White, NJ
core   +2 more sources

Cost-effectiveness of seasonal malaria chemoprevention in upper west region of Ghana [PDF]

Malaria Journal, 2016
In Ghana, malaria is endemic and perennial (with significant seasonal variations in the three Northern Regions), accounting for 33 % of all deaths among children under 5 years old, with prevalence rates in children under-five ranging from 11 % in Greater Accra to 40 % in Northern Region.
Nonvignon, Justice, Aryeetey, Genevieve Cecilia, Issah, Shamwill, Ansah, Patrick, Malm, Keziah L., Ofosu, Winfred, Tagoe, Titus, Agyemang, Samuel Agyei, Aikins, Moses   +8 more
openaire   +2 more sources

Nutritional status in young children prior to the malaria transmission season in Burkina Faso and Mali, and its impact on the incidence of clinical malaria

Malaria Journal, 2021
Background Malaria and malnutrition remain major problems in Sahel countries, especially in young children. The direct effect of malnutrition on malaria remains poorly understood, and may have important implications for malaria control.
Mariken de Wit, Matthew Cairns, Yves Daniel Compaoré, Issaka Sagara, Irene Kuepfer, Issaka Zongo, Amadou Barry, Modibo Diarra, Amadou Tapily, Samba Coumare, Ismaila Thera, Frederic Nikiema, R. Serge Yerbanga, Rosemonde M. Guissou, Halidou Tinto, Alassane Dicko, Daniel Chandramohan, Brian Greenwood, Jean Bosco Ouedraogo   +18 more
doaj   +1 more source

Feasibility and Coverage of Implementing Intermittent Preventive Treatment of Malaria in Pregnant women Contacting Private or Public Clinics in Tanzania: Experience-based Viewpoints of Health Managers in Mkuranga and Mufindi districts. [PDF]

, 2013
Evidence on healthcare managers' experience on operational feasibility of malaria intermittent preventive treatment for malaria during pregnancy (IPTp) using sulphadoxine-pyrimethamine (SP) in Africa is systematically inadequate.
A Hughes, A Vallely, AD Asante, AK Rowe, B Greenwood, C Menendez, C Pell, C Pell, C Quijada, C von Both, E Tambo, E Worrall, EANMAT - East Africa Network for Monitoring Anti-Malarial Treatment, ED Nsimba, EV Mbugi, FM Ringsted, FO ter Kuile, G Hobbs, G Mubyazi, G Mubyazi, G Mubyazi, G Mubyazi, GB Fosu, GM Mubyazi, GM Mubyazi, GM Mubyazi, GM Mubyazi, GM Mubyazi, GM Mubyazi, Godfrey M Mubyazi, H Tagbor, Health Research Action (HERA), J Hill, J Hill, J Hill, J Morse, J Smithson, J Webster, Jens Byskov, K Anders, K Gross, Malaria Consortium - Tanzania, Ministry of Health (MoH) – National Malaria Control Programme, MoH – Tanzania, MS Alilio, Pascal Magnussen, Paul Bloch, President’s Malaria Initiative (PMI), RBM - Roll Back Malaria - Tanzania, RK Yin, S Ugoh, SO Maluka, T Marchant, University of Copenhagen, Denmark, WHO, World Health Organization (WHO),, WP O’Meara   +56 more
core   +1 more source

Micronutrient Powders Combined With Malaria Chemoprevention to Improve Anaemia and Cognitive Function in Early Childhood in Mali: A Cluster‐Randomised Trial

Maternal &Child Nutrition, Volume 21, Issue 4, October 2025.
Globally nearly 40% of children under 5 years old are anaemic, which affects their ability to grow and develop. A cluster randomised trial was conducted in 60 communities in Southern Mali to evaluate the added impact of home fortification with micronutrient powders, delivered alongside seasonal malaria chemoprevention, on anaemia, malaria infection ...
Niélé H. Diarra, Yahia Dicko, Natalie Roschnik, Modibo Bamadio, Michael Boivin, Yvonne Griffiths, Rebecca Jones, Sham Lal, Helen Moestue, Hamidou Niangaly, Lauren Pisani, Renion Saye, Kalifa Sidibe, Karla Smuts, Nia‐An Philippe Thera, Josselin Thuilliez, Hans Verhoef, Moussa Sacko, Siân E. Clarke   +18 more
wiley   +1 more source