Results 81 to 90 of about 3,641 (196)

Tools and Strategies for Malaria Control and Elimination: What Do We Need to Achieve a Grand Convergence in Malaria? [PDF]

, 2016
Progress made in malaria control during the past decade has prompted increasing global dialogue on malaria elimination and eradication. The product development pipeline for malaria has never been stronger, with promising new tools to detect, treat, and ...
Achee, Nicole, Bell, David, Djimdé, Abdoulaye A., Hemingway, Janet, Qi, Gao, Shretta, Rima, Wells, Timothy N. C.   +6 more
core   +3 more sources

Use of population pharmacokinetic‐pharmacodynamic modelling to inform antimalarial dose optimization in infants

British Journal of Clinical Pharmacology, Volume 91, Issue 4, Page 968-980, April 2025.
Infants bear a significant malaria burden but are usually excluded from participating in early dose optimization studies that inform dosing regimens of antimalarial therapy. Unlike older children, infants' exclusion from early‐phase trials has resulted in limited evidence to guide accurate dosing of antimalarial treatment for uncomplicated malaria or ...
Clifford G. Banda, Joel Tarning, Karen I. Barnes   +2 more
wiley   +1 more source

Seasonal malaria chemoprevention in Africa and China’s upgraded role as a contributor: a scoping review

Infectious Diseases of Poverty, 2023
Abstract Background Children under five are the vulnerable population most at risk of being infected with Plasmodium parasites, especially in the Sahel region. Seasonal malaria chemoprevention (SMC) recommended by World Health Organization (WHO), has proven to be a highly effective intervention to prevent malaria.
Ming Xu, Yun-Xuan Hu, Shen-Ning Lu, Muhammad Abdullahi Idris, Shu-Duo Zhou, Jian Yang, Xiang-Ning Feng, Yang-Mu Huang, Xian Xu, Ying Chen, Duo-Quan Wang   +10 more
openaire   +3 more sources

Making the most of malaria chemoprevention

Malaria Journal
Against a backdrop of stalled progress in malaria control, it is surprising that the various forms of malaria chemoprevention are not more widely used. The World Health Organization (WHO) has recommended several malaria chemoprevention strategies, some ...
Jasper Littmann, Dorothy Achu, Miriam K. Laufer, Corine Karema, David Schellenberg   +4 more
doaj   +1 more source

Effect of seasonal malaria chemoprevention on the acquisition of antibodies to Plasmodium falciparum antigens in Ouelessebougou, Mali

Malaria Journal, 2017
Background Seasonal malaria chemoprevention (SMC) is a new strategy to reduce malaria burden in young children in Sahelian countries. It consists of the administration of full treatment courses of sulfadoxine–pyrimethamine plus amodiaquine to children at
Almahamoudou Mahamar, Djibrilla Issiaka, Amadou Barry, Oumar Attaher, Adama B. Dembele, Tiangoua Traore, Adama Sissoko, Sekouba Keita, Bacary Soumana Diarra, David L. Narum, Patrick E. Duffy, Alassane Dicko, Michal Fried   +12 more
doaj   +1 more source

Design, implementation and evaluation of a national campaign to distribute nine million free LLINs to children under five years of age in Tanzania. [PDF]

, 2011
BACKGROUND\ud \ud After a national voucher scheme in 2004 provided pregnant women and infants with highly subsidized insecticide-treated nets (ITNs), use among children under five years (U5s) in mainland Tanzania increased from 16% in 2004 to 26.2% in ...
Bonner, Kimberly, Mwita, Alex, McElroy, Peter D, Omari, Susan, Mzava, Ally, Lengeler, Christian, Kaspar, Naomi, Nathan, Rose, Ngegba, Joyce, Mtung'e, Romanus, Brown, Nick   +10 more
core   +2 more sources

Pharmacokinetics of a Novel Piperaquine Dispersible Granules Formulation Under Fasting and Various Fed Conditions Versus Piperaquine Tablets When Fasted in Healthy Tanzanian Adults: A Randomized, Phase I Study

Clinical and Translational Science, Volume 18, Issue 2, February 2025.
ABSTRACT Piperaquine tetraphosphate (PQP), a long‐acting antimalarial, is being considered in a combination for chemoprevention. Dihydroartemisinin‐piperaquine tablets (hard and dispersible) approved for the treatment of acute uncomplicated malaria should be administered in a fasted state, as PQP bioavailability increases with food.
Florence A. Milando, Said Jongo, Salim Abdulla, Gloria Nyaulingo, Anneth‐Mwasi Tumbo, Sarah Mswata, Juliether Tiago, Beatus S. Bongole, Ashura Mirambo, Kamaka Kassimu, Hussein Mbarak, Mohammed A. Rashid, Ali Hamad, Michael Mihayo, Tunu Ndanzi, Omary Zuberi, Naima Saadia, Mariam Somboka, Mariam Yamba‐Yamba, Theresia Ngonyani, Amina Nditi, Margaret Msuya, Bakari Mwalimu, Hajirani M. Msuya, Khamis Awadh, Ali Ali, Anne Claire Marrast, Denis Gossen, Alice Neequaye, Myriam El‐Gaaloul, Hanu Ramachandruni, Isabelle Borghini‐Fuhrer   +31 more
wiley   +1 more source

Evaluation of direct and indirect effects of seasonal malaria chemoprevention in Mali [PDF]

Scientific Reports, 2018
AbstractRandomized controlled trials have established that seasonal malaria chemoprevention (SMC) in children is a promising strategy to reduce malaria transmission in Sahelian West Africa. This strategy was recently introduced in a dozen countries, and about 12 million children received SMC in 2016. However, evidence on SMC effectiveness under routine
openaire   +3 more sources

The use of video job-aids to improve the quality of seasonal malaria chemoprevention delivery

PLOS Digital Health, 2022
Mobile phones are increasingly used in community health programmes, but the use of video job-aids that can be displayed on smart phones has not been widely exploited. We investigated the use of video job-aids to support the delivery of seasonal malaria chemoprevention (SMC) in countries in West and Central Africa. The study was prompted by the need for
Susana Scott, Bienvenu Salim Camara, Michael Hill, Eugène Kaman Lama, Lansana Barry, Aurore Ogouyemi-Hounto, William Houndjo, Gauthier Tougri, Nombre Yacouba, Dorothy Achu, Marcellin Ateba, Mahamat Saleh Issakha Diar, Keziah L. Malm, Kofi Adomako, Paolo Djata, Wica Da Silva, Idrissa Cissé, Vincent Sanogo, Hadiza Jackou, Nnenna Ogbulafor, Bala M. Adu, Jamilu Nikau, Seynabou Gaye, Alioune Badara Gueye, Balla Kandeh, Olimatou Kolley, Tinah Atcha-Oubou, Tchassama Tchadjobo, Kovana Marcel Loua, Andre-Marie Tchouatieu, Ibrahima Mbaye, Maria-Angeles Lima-Parra, Abena Poku-Awuku, Jean Louis Ndiaye, Corinne Merle, Liz Thomas, Paul Milligan   +36 more
openaire   +5 more sources

Population impact of malaria control interventions in the health district of Kati, Mali.

PLoS ONE
BackgroundWHO and its partners have adopted alternative control interventions since the failure to eradicate malaria worldwide in the 1960s and 1970s.
Abdoulaye Katile, Issaka Sagara, Mady Cissoko, Cédric Stéphane Bationo, Mathias Dolo, Pascal Dembélé, Bourama Kamate, Ismaila Simaga, Mahamadou Soumana Sissoko, Jordi Landier, Jean Gaudart   +10 more
doaj   +1 more source