Results 11 to 20 of about 3,641 (196)

Seasonal malaria chemoprevention: successes and missed opportunities [PDF]

Malaria Journal, 2017
Seasonal malaria chemoprevention (SMC) was recommended in 2012 for young children in the Sahel during the peak malaria transmission season. Children are given a single dose of sulfadoxine/pyrimethamine combined with a 3-day course of amodiaquine, once a ...
Matthew E. Coldiron, Lorenz Von Seidlein, Rebecca F. Grais   +2 more
doaj   +3 more sources

Seasonal Malaria Chemoprevention: An Evolving Research Paradigm.

PLoS Medicine, 2016
Robert W. Snow discusses the importance of empirical evidence, such as that provided in the trial published this week by Milligan and colleagues, in guiding malaria control in Africa.
Robert W Snow
doaj   +4 more sources

Trends in uncomplicated and severe malaria following seasonal malaria chemoprevention administration in Nouna, Burkina Faso: a quasi-experimental pre-post study [PDF]

Malaria Journal
Background While Seasonal Malaria Chemoprevention (SMC) has been adopted as a malaria control strategy in regions with seasonal transmission, continued monitoring and evaluation of its effectiveness across diverse ecological, epidemiological, and ...
Elisabeth A. Gebreegziabher, Mamadou Ouattara, Mamadou Bountogo, Boubacar Coulibaly, Valentin Boudo, Thierry Ouedraogo, Elodie Lebas, Huiyu Hu, David V. Glidden, Benjamin F. Arnold, Thomas M. Lietman, Ali Sié, Catherine E. Oldenburg   +12 more
doaj   +2 more sources

Status and prospects of seasonal malaria chemoprevention among children in Sahelian countries: A systematic review and meta-analysis. [PDF]

PLOS Global Public Health
In areas with seasonal malaria transmission, seasonal malaria chemoprevention (SMC) involves giving children a three-day course of sulfadoxine-pyrimethamine and amodiaquine once a month during the transmission season.
Medard Djedanem, Noura Mamane Salé, Elhadji Yacoudima Yacoubou Mahaman Aminou, Jean Testa, Ronan Jambou   +4 more
doaj   +2 more sources

Combining seasonal malaria chemoprevention with novel therapeutics for malaria prevention: a mathematical modelling study. [PDF]

PLoS Comput Biol
Abstract Vaccines, monoclonal antibodies, and long-acting injectables are being developed to prevent Plasmodium falciparum malaria. These therapeutics may target multiple stages of the parasite life cycle; evidence is needed to articulate their benefits with chemoprevention and ...
Braunack-Mayer L, Malinga J, Nekkab N, Kelly SL, Möhrle JJ, Penny MA.   +5 more
europepmc   +4 more sources

Parasitological efficacy of seasonal malaria chemoprevention in Nampula, northern Mozambique. [PDF]

Trans R Soc Trop Med Hyg
Abstract Background Deployment of seasonal malaria chemoprevention (SMC) for young children using monthly sulphadoxine-pyrimethamine-amodiaquine (SPAQ) has recently been extended to Central and East Africa.
Bonnington C, Sitoe M, Pulido Tarquino IA, Enosse SM, Sararat C, Suwannasin K, Proux S, Koesukwiwat U, Tarning J, Imwong M, Theiss-Nyland K, Nosten FH, White NJ.   +12 more
europepmc   +3 more sources

Effect of Adding Azithromycin to Seasonal Malaria Chemoprevention [PDF]

New England Journal of Medicine, 2019
Mass administration of azithromycin for trachoma control led to a sustained reduction in all-cause mortality among Ethiopian children. Whether the addition of azithromycin to the monthly sulfadoxine-pyrimethamine plus amodiaquine used for seasonal malaria chemoprevention could reduce mortality and morbidity among African children was unclear.We ...
Daniel Chandramohan, Alassane Dicko, Issaka Zongo   +2 more
exaly   +3 more sources

Systematic review on the cost of seasonal malaria chemoprevention (SMC). [PDF]

Malar J
Implemented in 17 countries to date, seasonal malaria chemoprevention (SMC) is a recommended strategy to prevent childhood malaria in areas with seasonal transmission of P. falciparum through monthly administration of antimalarial medicines. Understanding the costs and resource requirements of SMC delivery is necessary for effective planning and ...
Ruisch A, Iodice M, Mathur I, Harris S, Walker DG, Owusu R, Nonvignon J, Gilmartin C.   +7 more
europepmc   +4 more sources

School-aged children based seasonal malaria chemoprevention using artesunate-amodiaquine in Mali

Parasite Epidemiology and Control, 2018
Introduction: Malaria is still a public health problem in Africa. Seasonal Malaria Chemoprevention (SMC) is an efficient control strategy recommended by WHO that targets children under five year old living in areas of seasonal malaria transmission.
Mahamadou Ali Thera, Abdoulaye K Kone
exaly   +3 more sources

Seasonal Malaria Chemoprevention Implementation: Effect on Malaria Incidence and Immunity in a Context of Expansion of P. falciparum Resistant Genotypes with Potential Reduction of the Effectiveness in Sub-Saharan Africa

Infection and Drug Resistance, 2022
Séni Nikiema,1,2 Issiaka Soulama,1,3 Salif Sombié,1 André-Marie Tchouatieu,4 Samuel Sindie Sermé,5 Noëlie Béré Henry,5 Nicolas Ouedraogo,1 Nathalie Ouaré,1,6 Raissa Ily,1,6 Oumarou Ouédraogo,3 Dramane Zongo,3 Florencia Wendkuuni Djigma,2 Alfred B Tiono,1
Issiaka SOULAMA, Dramane ZONGO, Jacques Simpore   +2 more
exaly   +2 more sources