Results 41 to 50 of about 3,641 (196)

Improved housing versus usual practice for additional protection against clinical malaria in The Gambia (RooPfs): a household-randomised controlled trial

open access: yesThe Lancet Planetary Health, 2021
Summary: Background: In malaria-endemic areas, residents of modern houses have less malaria than those living in traditional houses. We aimed to assess whether children in The Gambia received an incremental benefit from improved housing, where current ...
Margaret Pinder, PhD   +13 more
doaj   +1 more source

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial. [PDF]

open access: yes, 2018
BACKGROUND: Primaquine and methylene blue are gametocytocidal compounds that could prevent Plasmodium falciparum transmission to mosquitoes. We aimed to assess the efficacy and safety of primaquine and methylene blue in preventing human to mosquito ...
Bousema, Teun   +22 more
core   +2 more sources

Epidemiology of malaria in an area of seasonal transmission in Niger and implications for the design of a seasonal malaria chemoprevention strategy [PDF]

open access: yesMalaria Journal, 2013
Abstract Background Few data are available about malaria epidemiological situation in Niger. However, implementation of new strategies such as vaccination or seasonal treatment of a target population requires the knowledge of baseline epidemiological features of malaria.
Guillebaud, Julia   +10 more
openaire   +4 more sources

Seasonal malaria chemoprevention in an area of extended seasonal transmission in Ashanti, Ghana: an individually randomised clinical trial. [PDF]

open access: yes, 2015
OBJECTIVE: To investigate the effectiveness of seasonal malaria chemoprevention (SMC) and community case management with long-acting artemisinin-based combination therapies (ACTs) for the control of malaria in areas of extended seasonal malaria ...
Acheampong, Princess Ruhama   +5 more
core   +1 more source

Effectiveness of malaria control programs in West Africa: a narrative review [PDF]

open access: yesInfectious Diseases and Tropical Medicine, 2022
Malaria is a major public health challenge in Africa, especially in West African countries. Its impacts on the individuals and families in these countries go beyond the physical health status to the financial crises it leaves them to nurse.
T. Sokunbi, T. Adesanya, F. Aremu
doaj   +1 more source

New tools for malaria control - using them wisely. [PDF]

open access: yes, 2017
The incidence of malaria in sub-Saharan Africa is falling and in many countries on the continent the pattern of malaria infection within the country is becoming more heterogeneous.
Greenwood, Brian
core   +1 more source

Intermittent preventive treatment with dihydroartemisinin-piperaquine in Ugandan schoolchildren selects for Plasmodium falciparum transporter polymorphisms that modify drug sensitivity. [PDF]

open access: yes, 2016
Dihydroartemisinin-piperaquine (DP) offers prolonged protection against malaria, but its impact on Plasmodium falciparum drug sensitivity is uncertain. In a trial of intermittent preventive treatment in schoolchildren in Tororo, Uganda, in 2011 to 2012 ...
Brooker, SJ   +11 more
core   +3 more sources

Malaria in school-age children in Africa: an increasingly important challenge. [PDF]

open access: yes, 2014
School-age children have attracted relatively little attention as a group in need of special measures to protect them against malaria. However, increasing success in lowering the level of malaria transmission in many previously highly endemic areas will ...
Brooker, Simon J   +6 more
core   +2 more sources

Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]

open access: yesThe Journal of Infectious Diseases, 2019
Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Oumar, Attaher   +18 more
openaire   +2 more sources

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