Results 41 to 50 of about 651,382 (186)
Combining malaria vaccination with chemoprevention: a promising new approach to malaria control
Malaria Journal, 2021 Malaria control has stalled in a number of African countries and novel approaches to malaria control are needed for these areas. The encouraging results of a recent trial conducted in young children in Burkina Faso and Mali in which a combination of the ...
Brian Greenwood +8 more
doaj +1 more source
The Lancet Planetary Health, 2021 Summary: Background: In malaria-endemic areas, residents of modern houses have less malaria than those living in traditional houses. We aimed to assess whether children in The Gambia received an incremental benefit from improved housing, where current ...
Margaret Pinder, PhD +13 more
doaj +1 more source
Malaria intervention scale-up in Africa : effectiveness predictions for health programme planning tools, based on dynamic transmission modelling [PDF]
, 2016 Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-based.
Richard Cibulskis +24 more
core +1 more source
Seasonal vaccination against malaria: a potential use for an imperfect malaria vaccine
Malaria Journal, 2017 In many parts of the African Sahel and sub-Sahel, where malaria remains a major cause of mortality and morbidity, transmission of the infection is highly seasonal.
Brian Greenwood +10 more
doaj +1 more source
Effectiveness of malaria control programs in West Africa: a narrative review [PDF]
Infectious Diseases and Tropical Medicine, 2022 Malaria is a major public health challenge in Africa, especially in West African countries. Its impacts on the individuals and families in these countries go beyond the physical health status to the financial crises it leaves them to nurse.
T. Sokunbi, T. Adesanya, F. Aremu
doaj +1 more source
Efficacy and safety of artemether-lumefantrine for the treatment of uncomplicated malaria in the setting of three different chemopreventive regimens. [PDF]
, 2015 BACKGROUND: The burden of malaria remains high for children in parts of Africa despite the use of insecticide-treated bed nets (ITNs). Chemoprevention has the potential of reducing the malaria burden; however, limited data exist on the efficacy and ...
Tamara Clark +17 more
core +1 more source
Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]
The Journal of Infectious Diseases, 2019 Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Oumar, Attaher +18 more
openaire +2 more sources
A proposed method of grading malaria chemoprevention efficacy [PDF]
, 2023 The efficacy and effectiveness of antimalarial drugs are threatened by increasing levels of resistance and therefore require continuous monitoring. Chemoprevention is increasingly deployed as a malaria control measure, but there are no generally accepted
C Bonnington +5 more
core +1 more source
BMC Infectious Diseases, 2019 Background The only licensed malaria vaccine, RTS,S/AS01, has been developed for morbidity-control in young children. The potential impact on transmission of deploying such anti-infective vaccines to wider age ranges, possibly with co-administration of ...
Flavia Camponovo +3 more
doaj +1 more source
Seasonal Malaria Chemoprevention Coverage in Guinea in 2019 [PDF]
, 2020 SMC involves the administration of a treatment course of sulfadoxine-pyrimethamine plus amodiaquine once a month to children aged 3–59 months during the high risk period each year to prevent malaria. SMC over 4 months of the year was introduced in Guinea in 2015 in 6 prefectures, scaling up to 13 prefectures by 2018. The present survey was conducted at
Loua, Kovana Marcel, Milligan, Paul
openaire +1 more source