Results 51 to 60 of about 555,914 (187)

Systematic Review and Meta-Analysis of Seasonal Malaria Chemoprevention. [PDF]

Am J Trop Med Hyg
ABSTRACT. Seasonal malaria chemoprevention (SMC) for children under 5 years of age for up to four monthly cycles during malaria transmission season was recommended by the WHO in 2012 and has been implemented in 13 countries in the Sahel, reaching more than 30 million children annually.
Thwing J, Williamson J, Cavros I, Gutman JR.   +3 more
europepmc   +3 more sources

Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]

The Journal of Infectious Diseases, 2019
Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Oumar, Attaher, Irfan, Zaidi, Jennifer L, Kwan, Djibrilla, Issiaka, Mamoudou B, Samassekou, Kadidia B, Cisse, Barou, Coulibaly, Sekouba, Keita, Sibiri, Sissoko, Tiangoua, Traore, Kalifa, Diarra, Bacary S, Diarra, Adama, Dembele, Moussa B, Kanoute, Almahamoudou, Mahamar, Amadou, Barry, Michal, Fried, Alassane, Dicko, Patrick E, Duffy   +18 more
openaire   +2 more sources

Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial. [PDF]

, 2008
BACKGROUND: Malaria and anaemia are the leading causes of morbidity and mortality in children in sub-Saharan Africa. We have investigated the effect of intermittent preventive treatment with sulphadoxine-pyrimethamine or artesunate plus amodiaquine on ...
Kweku Margaret, Liu Dongmei, Adjuik, Martin, Daniel Chandramohan, Greenwood Brian, Margaret Kweku, Binka Fred, Fred Binka, Binka, Fred, Chandramohan, Daniel, Mahmood Seidu, Liu, Dongmei, Dongmei Liu, Seidu, Mahmood, Martin Adjuik, Greenwood, Brian, Brian Greenwood, Kweku, Margaret, Seidu Mahmood, Adjuik Martin, Chandramohan Daniel   +20 more
core   +1 more source

Mass campaigns combining antimalarial drugs and anti-infective vaccines as seasonal interventions for malaria control, elimination and prevention of resurgence: a modelling study

BMC Infectious Diseases, 2019
Background The only licensed malaria vaccine, RTS,S/AS01, has been developed for morbidity-control in young children. The potential impact on transmission of deploying such anti-infective vaccines to wider age ranges, possibly with co-administration of ...
Flavia Camponovo, Chris F. Ockenhouse, Cynthia Lee, Melissa A. Penny   +3 more
doaj   +1 more source

Seasonal Malaria Chemoprevention Coverage in Guinea in 2019 [PDF]

, 2020
SMC involves the administration of a treatment course of sulfadoxine-pyrimethamine plus amodiaquine once a month to children aged 3–59 months during the high risk period each year to prevent malaria. SMC over 4 months of the year was introduced in Guinea in 2015 in 6 prefectures, scaling up to 13 prefectures by 2018. The present survey was conducted at
Loua, Kovana Marcel, Milligan, Paul
openaire   +1 more source

Temporal Variations in Malaria Risk in Africa [PDF]

, 2007
In sub-Saharan Africa, malaria is a major cause of morbidity and mortality especially among children less than five years of age and pregnant women. Malaria situations are very diverse because of many factors involved in malaria transmission and the ...
Mabaso, Musawenkosi L. H.
core   +1 more source

Seasonal malaria vaccination: protocol of a phase 3 trial of seasonal vaccination with the RTS,S/AS01 _E vaccine, seasonal malaria chemoprevention and the combination of vaccination and chemoprevention

BMJ Open, 2020
Introduction Seasonal malaria chemoprevention (SMC), with sulphadoxine–pyrimethamine plus amodiaquine (SP+AQ) is effective but does not provide complete protection against clinical malaria.
Ismaila Thera, Irene Kuepfer, Daniel Chandramohan, Alassane Dicko, Issaka Zongo, Issaka Sagara, Matthew Cairns, Modibo Diarra, Amadou Tapily, Djibrilla Issiaka, Koualy Sanogo, Almahamoudou Mahamar, Frederic Sompougdou, Serge Yerbanga, Paul Milligan, Halidou Tinto, Opokua Ofori-Anyinam, Jean-Bosco Ouedraogo, B Greenwood   +18 more
openaire   +3 more sources

Seasonal malaria chemoprevention in Africa and China's upgraded role as a contributor: a scoping review. [PDF]

Infect Dis Poverty, 2023
Abstract Background Children under five are the vulnerable population most at risk of being infected with Plasmodium parasites, especially in the Sahel region. Seasonal malaria chemoprevention (SMC) recommended by World Health Organization (WHO), has proven to be a highly effective intervention to prevent malaria.
Xu M, Hu YX, Lu SN, Idris MA, Zhou SD, Yang J, Feng XN, Huang YM, Xu X, Chen Y, Wang DQ.   +10 more
europepmc   +4 more sources

Longitudinal analysis of the capacities of community health workers mobilized for seasonal malaria chemoprevention in Burkina Faso [PDF]

, 2020
Results of the study confirm the capacity of community health workers, or “community-based distributors” (CBDs), under routine programme implementation of seasonal malaria chemoprevention (SMC).
Kombate, Gountante, Chetaille, Gaël, Bicaba, Abel, Haddad, Slim, Bila, Alice, Serme, Luc   +5 more
core   +1 more source

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Issa N Ouédraogo, Tiono, Alfred B, Youssouf Kaboré, Daniel Chandramohan, Yaro Jean Baptiste, Ouédraogo, Amidou Z, Soulama, Issiaka, Konaté Amadou T., Issa N. Ouédraogo, Ouédraogo Issa N., Amadou T Konaté, Yaro, Jean Baptiste, Gansané, Adama, Ouédraogo Espérance, Alfred B. Tiono, Jean Baptiste Yaro, Diadier A. Diallo, Greenwood, Brian, Diallo Diadier A., Espérance Ouédraogo, Chandramohan Daniel, Ouédraogo, Alphonse, Cousens, Simon, Diadier A Diallo, Greenwood Brian, Alfred B Tiono, David T. Kangoyé, Ouédraogo, Espérance, Chandramohan, Daniel, Paul J Milligan, Kaboré, Youssouf, Ouédraogo Alphonse, Amadou T. Konaté, Sirima Sodiomon B., Amidou Z Ouédraogo, Kangoyé, David T, Sirima, Sodiomon B, Diarra, Amidou, Ouédraogo, Issa N, Paul J. Milligan, Sodiomon B. Sirima, Kangoyé David T., Milligan Paul J., Milligan, Paul J, Cousens Simon, Alphonse Ouédraogo, Simon Cousens, Diallo, Diadier A, Brian Greenwood, Amidou Z. Ouédraogo, Adama Gansané, Tiono Alfred B., Kaboré Youssouf, Sodiomon B Sirima, Gansané Adama, David T Kangoyé, Issiaka Soulama, Ouédraogo Amidou Z., Soulama Issiaka, Amidou Diarra, Konaté, Amadou T, Diarra Amidou   +61 more
core   +1 more source