Results 51 to 60 of about 686,514 (182)

Delivery strategies for malaria vaccination in areas with seasonal malaria transmission

open access: yesBMJ Global Health, 2023
Background Seasonal vaccination with the RTS,S/AS01E malaria vaccine given alongside seasonal malaria chemoprevention (SMC) substantially reduces malaria in young children.
Jayne Webster   +9 more
doaj   +1 more source

Implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission: workshop meeting report

open access: yesMalaria Journal, 2023
A workshop on implementation strategies for the introduction of the RTS,S/AS01 (RTS,S) malaria vaccine in countries with areas of highly seasonal transmission, was held as a hybrid meeting in Dakar, Senegal, and online, 23–25 January 2023. Delegates from
Corinne S. Merle, RTSS-SMC working group
doaj   +1 more source

Sub-national tailoring of seasonal malaria chemoprevention in Mali based on malaria surveillance and rainfall data

open access: yesParasites & Vectors, 2022
Abstract Background In malaria endemic countries, seasonal malaria chemoprevention (SMC) interventions are performed during the high malaria transmission in accordance with epidemiological surveillance data. In this study we propose a predictive approach for tailoring the timing and number of cycles of SMC in all health ...
Cissoko, Mady   +15 more
openaire   +4 more sources

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

open access: yesMalaria Journal, 2020
Background Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the health system.
Djibrilla Issiaka   +9 more
doaj   +1 more source

Preliminary Analysis of the Impact of Malaria Vaccine Introduction on Severe Malaria Incidence in Children Under 5 Years in the Health Districts of Edea, Japoma, and Mbanga (2020–2024)

open access: yesHealth Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims The RTS,S/AS01 malaria vaccine (MV) was introduced in Cameroon on 22 January 2024 in 42 of 200 health districts, including three in the Littoral Region (Edea, Japoma and Mbanga). This study describes early trends in severe malaria among children under 5 years of age in these three districts of the Littoral Region and ...
Alex Stéphane Ndjip Ndjock   +6 more
wiley   +1 more source

Longitudinal analysis of the capacities of community health workers mobilized for seasonal malaria chemoprevention in Burkina Faso [PDF]

open access: yes, 2020
Results of the study confirm the capacity of community health workers, or “community-based distributors” (CBDs), under routine programme implementation of seasonal malaria chemoprevention (SMC).
Kombate, Gountante   +5 more
core   +1 more source

Hydroxamic Acids as HDAC Inhibitor Drug Leads for Malaria

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1477-1498, November 2026.
ABSTRACT Malaria is a global health threat, with an estimated 282 million cases and 610,000 malaria‐associated deaths reported in 2024. Most mortality is due to infection by Plasmodium falciparum parasites, with the highest burden occurring in Sub‐Saharan Africa.
Wisam A. Dawood   +7 more
wiley   +1 more source

Seasonal Malaria Chemoprevention in Guinea in 2020: coverage survey results [PDF]

open access: yes, 2021
In 2020 SMC was implemented in 17 out of 33 prefectures, which include 50% of the population outside the city of Conakry. The COVID-19 pandemic, and the presidential elections in Guinea, could potentially have affected SMC campaigns in 2020, it was therefore important to evaluate coverage of SMC given these challenges and the increased area of ...
Loua, Kovana Marcel, Milligan, Paul
openaire   +1 more source

Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali [PDF]

open access: yes, 2016
Seasonal malaria chemoprevention (SMC) with sulphadoxine-pyrimethamine (SP) plus amodiaquine (AQ) is being scaled up in Sahelian countries of West Africa.
Nouhoum Diallo   +56 more
core   +1 more source

Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger

open access: yesMalaria Journal, 2021
Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha   +7 more
doaj   +1 more source

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