Results 31 to 40 of about 555,914 (187)

Facilitators and Barriers to Uptake of an Extended Seasonal Malaria Chemoprevention Programme in Ghana: A Qualitative Study of Caregivers and Community Health Workers.

PLoS ONE, 2016
BackgroundSeasonal Malaria Chemoprevention (SMC) is currently recommended for children under five in areas where malaria transmission is highly seasonal.
Gifty D Antwi, Laura A Bates, Rebecca King, Princess R Mahama, Harry Tagbor, Matt Cairns, James N Newell   +6 more
doaj   +2 more sources

Evaluating the effectiveness and cost-effectiveness of integrating mass drug administration for helminth control with seasonal malaria chemoprevention in Ghanaian children: Protocol for a cluster randomised controlled trial. [PDF]

Trop Med Int Health
Abstract Objectives To evaluate the effectiveness and cost‐effectiveness of integrating seasonal malaria chemoprevention (SMC) with mass drug administration for helminth control among school‐aged children living in communities where the burden of malaria and helminths is high in Ghana, West Africa.
Afolabi MO, Adu-Gyasi D, Paintain L, Tawiah T, Ali MS, Greenwood B, Asante KP.   +6 more
europepmc   +2 more sources

Effect of seasonal malaria chemoprevention on incidence of malaria among children under five years in Kotido and Moroto Districts, Uganda, 2021: time series analysis [PDF]

Malaria Journal
Background Seasonal malaria chemoprevention (SMC) refers to monthly administration of full treatment courses of anti-malarial medicine to children
Andrew Kwiringira, Benon Kwesiga, Richard Migisha, Lilian Bulage, Daniel Kadobera, Damian Rutazaana, Julie R. Harris, Alex R. Ario, Julius Ssempiira   +8 more
doaj   +2 more sources

Asymptomatic Plasmodium falciparum infections and determinants of carriage in a seasonal malaria chemoprevention setting in Northern Cameroon and south Senegal (Kedougou) [PDF]

Malaria Journal
Background Among the several strategies recommended for the fight against malaria, seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine combination (SPAQ) targets children 3 months to 5 years in Sahel regions of Africa to
Innocent M. Ali, Isaac A. Manga, Akindeh M. Nji, Valery P. Tchuenkam, Peter Thelma Ngwa Neba, Dorothy F. Achu, Jude D. Bigoga, Babacar Faye, Cally Roper, Colin J. Sutherland, Wilfred F. Mbacham   +10 more
doaj   +2 more sources

Combining seasonal malaria chemoprevention with novel therapeutics for malaria prevention: a mathematical modelling study. [PDF]

PLoS Comput Biol
Abstract Vaccines, monoclonal antibodies, and long-acting injectables are being developed to prevent Plasmodium falciparum malaria. These therapeutics may target multiple stages of the parasite life cycle; evidence is needed to articulate their benefits with chemoprevention and ...
Braunack-Mayer L, Malinga J, Nekkab N, Kelly SL, Möhrle JJ, Penny MA.   +5 more
europepmc   +5 more sources

Seasonal malaria chemoprevention in northern Mozambique: a cost-effectiveness analysis. [PDF]

Malar J
Abstract Background Malaria is endemic in Mozambique and one of the leading causes of death in children under 5 years old. In 2020 the country adopted the WHO-recommended seasonal malaria chemoprevention (SMC) strategy and delivered the intervention in all 23 districts of Nampula province between January and April ...
Canana N, Tarquino IAP, Enosse S, Baker K, Rodrigues M, Rassi C, Chauhan AS, Nnaji C, Candrinho B, Maffioli EM.   +9 more
europepmc   +4 more sources

Malaria chemoprevention and drug resistance: a review of the literature and policy implications

Malaria Journal, 2022
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-malarial drugs used for chemoprevention is perennially threatened by drug resistance.
Christopher V. Plowe
doaj   +1 more source

Household-level effects of seasonal malaria chemoprevention in the Gambia. [PDF]

Commun Med (Lond), 2023
Abstract Background In 2022 the WHO recommended the discretionary expansion of the eligible age range for seasonal malaria chemoprevention (SMC) to children older than 4 years. Older children are at lower risk of clinical disease and severe malaria so there has been uncertainty about the cost ...
Soremekun S, Conteh B, Nyassi A, Soumare HM, Etoketim B, Ndiath MO, Bradley J, D'Alessandro U, Bousema T, Erhart A, Moreno M, Drakeley C.   +11 more
europepmc   +7 more sources

A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research, 2023
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly seasonal ...
Craig Bonnington, Sol Richardson, Godfrey Magumba, Christian Rassi, Jane Nabakooza, Denis Rubahika, Anthony Nuwa, James Tibenderana, Jimmy Opigo, Jane Achan, Richard Kajubi, Kevin Baker, Jennifer Ainsworth   +12 more
doaj   +1 more source

Systematic review on the cost of seasonal malaria chemoprevention (SMC). [PDF]

Malar J
Implemented in 17 countries to date, seasonal malaria chemoprevention (SMC) is a recommended strategy to prevent childhood malaria in areas with seasonal transmission of P. falciparum through monthly administration of antimalarial medicines. Understanding the costs and resource requirements of SMC delivery is necessary for effective planning and ...
Ruisch A, Iodice M, Mathur I, Harris S, Walker DG, Owusu R, Nonvignon J, Gilmartin C.   +7 more
europepmc   +4 more sources