Asymptomatic Plasmodium falciparum infections and determinants of carriage in a seasonal malaria chemoprevention setting in Northern Cameroon and south Senegal (Kedougou) [PDF]
Malaria JournalBackground Among the several strategies recommended for the fight against malaria, seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine combination (SPAQ) targets children 3 months to 5 years in Sahel regions of Africa to
Innocent M. Ali +10 more
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A proposed method of grading malaria chemoprevention efficacy [PDF]
, 2023 The efficacy and effectiveness of antimalarial drugs are threatened by increasing levels of resistance and therefore require continuous monitoring. Chemoprevention is increasingly deployed as a malaria control measure, but there are no generally accepted
C Bonnington, N J White, F H Nosten
core +1 more source
Shifts in the clinical epidemiology of severe malaria after scaling up control strategies in Mali
Frontiers in Neurology, 2022 A decrease in malaria incidence following implementation of control strategies such as use of artemisinin-based combination therapies, insecticide-impregnated nets, intermittent preventive treatment during pregnancy and seasonal malaria chemoprevention ...
Drissa Coulibaly +14 more
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Impact of seasonal malaria chemoprevention on prevalence of malaria infection in malaria indicator surveys in Burkina Faso and Nigeria [PDF]
BMJ Global Health, 2022 Background In 2012, the WHO issued a policy recommendation for the use of seasonal malaria chemoprevention (SMC) to children 3–59 months in areas of highly seasonal malaria transmission. Clinical trials have found SMC to prevent around 75% of clinical malaria.
Monica Anna de Cola +12 more
openaire +4 more sources
The Lancet Planetary Health, 2021 Summary: Background: In malaria-endemic areas, residents of modern houses have less malaria than those living in traditional houses. We aimed to assess whether children in The Gambia received an incremental benefit from improved housing, where current ...
Margaret Pinder, PhD +13 more
doaj +1 more source
Epidemiology of malaria in an area of seasonal transmission in Niger and implications for the design of a seasonal malaria chemoprevention strategy [PDF]
Malaria Journal, 2013 Abstract Background Few data are available about malaria epidemiological situation in Niger. However, implementation of new strategies such as vaccination or seasonal treatment of a target population requires the knowledge of baseline epidemiological features of malaria.
Guillebaud, Julia +10 more
openaire +4 more sources
Seasonal vaccination against malaria: a potential use for an imperfect malaria vaccine
Malaria Journal, 2017 In many parts of the African Sahel and sub-Sahel, where malaria remains a major cause of mortality and morbidity, transmission of the infection is highly seasonal.
Brian Greenwood +10 more
doaj +1 more source
Effectiveness of malaria control programs in West Africa: a narrative review [PDF]
Infectious Diseases and Tropical Medicine, 2022 Malaria is a major public health challenge in Africa, especially in West African countries. Its impacts on the individuals and families in these countries go beyond the physical health status to the financial crises it leaves them to nurse.
T. Sokunbi, T. Adesanya, F. Aremu
doaj +1 more source
Effect of Seasonal Malaria Chemoprevention on Immune Markers of Exhaustion and Regulation [PDF]
The Journal of Infectious Diseases, 2019 Abstract Background Seasonal malaria chemoprevention (SMC) is a novel strategy to reduce malaria infections in children. Infection with Plasmodium falciparum results in immune dysfunction characterized by elevated expression of markers associated with exhaustion, such as PD1 and LAG3, and regulatory ...
Oumar, Attaher +18 more
openaire +2 more sources
BMC Infectious Diseases, 2019 Background The only licensed malaria vaccine, RTS,S/AS01, has been developed for morbidity-control in young children. The potential impact on transmission of deploying such anti-infective vaccines to wider age ranges, possibly with co-administration of ...
Flavia Camponovo +3 more
doaj +1 more source