Results 21 to 30 of about 288 (84)

Impact of seasonal malaria chemoprevention on hospital admissions and mortality in children under 5 years of age in Ouelessebougou, Mali

Malaria Journal, 2020
Background Seasonal malaria chemoprevention is widely implemented in Sahel and sub-Sahel countries in Africa. Few studies have assessed the impact of the SMC on hospital admission and death when it is implemented in the health system.
Djibrilla Issiaka, Amadou Barry, Tiangoua Traore, Boubacar Diarra, David Cook, Mohamed Keita, Issaka Sagara, Patrick Duffy, Michal Fried, Alassane Dicko   +9 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Evidence that seasonal malaria chemoprevention with SPAQ influences blood and pre-erythrocytic stage antibody responses of Plasmodium falciparum infections in Niger

Malaria Journal, 2021
Background In endemic areas, children develop slowly and naturally anti-Plasmodium antibodies and become semi-immune. Seasonal Malaria Chemoprevention (SMC) with sulfadoxine-pyrimethamine + amodiaquine (SPAQ) is a new strategy to reduce malaria morbidity
Lamine Mahaman Moustapha, Rafiou Adamou, Maman Laminou Ibrahim, Mariama Abdoulaye Louis Padounou, Abdoulaye Diallo, David Courtin, Jean Testa, Jean Louis Abdourahim Ndiaye   +7 more
doaj   +1 more source

A 5‐Year Retrospective Morbidity Profile of School‐Aged Children at Ho Polyclinic, Volta Region, Ghana: Skin Conditions, Malaria, and Respiratory Illnesses as Leading Causes (2018–2022)

Public Health Challenges, Volume 5, Issue 3, September 2026.
Analysis of 10,428 outpatient consultations among school‐aged children attending Ho Polyclinic, Ghana (2018–2022), showed that three conditions accounted for 77.4% of all morbidity: skin conditions (38.3%), malaria (23.0%), and respiratory conditions (16.1%).
Anthoinette Adesope Ekuban, Frank Baiden
wiley   +1 more source

Geostatistical Modelling and Web‐Based Mapping of Malaria Risks Among Children Under Five Years in Nigeria: Evidence From the 2021 Nigeria Malaria Indicator Survey

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Malaria is a critical public health concern in Nigeria with the country bearing an uneven burden of the disease. In Nigeria, malaria is one of the main causes of child mortality and despite all efforts to reduce malaria mortality rates, the disease remains a major concern, notably among children under‐fives.
Justice Moses K. Aheto, Bakare Emmanuel Afolabi, Dolapo O. Oniyelu, Deborah O. Daniel, Steven I. Ikediashi, Oluwaseun A. Mogbojuri, Ronke D. Olorunfemi, Sodiq A. Orogun, Afeez Abidemi, Idowu I. Olasupo, Samuel A. Osikoya, Samuel A. Adeyemi, Hapiness O. Ismail, Isaac Bakare, Samson O. Olagbami, Dolapo A. Bakare, Baiyeri Samuel, Temitayo V. Irewole, Oluwafunmilayo O. Olapade, Oluwafolakemi Odunola, Oghenekevwe R. Ajewole, Joshua P. Ojo, Segun Oyedeji, Wisdom Takramah   +23 more
wiley   +1 more source

Seasonal Malaria Chemoprevention: An Evolving Research Paradigm.

PLoS Medicine, 2016
Robert W. Snow discusses the importance of empirical evidence, such as that provided in the trial published this week by Milligan and colleagues, in guiding malaria control in Africa.
Robert W Snow
doaj   +1 more source

Nutritional status in young children prior to the malaria transmission season in Burkina Faso and Mali, and its impact on the incidence of clinical malaria

Malaria Journal, 2021
Background Malaria and malnutrition remain major problems in Sahel countries, especially in young children. The direct effect of malnutrition on malaria remains poorly understood, and may have important implications for malaria control.
Mariken de Wit, Matthew Cairns, Yves Daniel Compaoré, Issaka Sagara, Irene Kuepfer, Issaka Zongo, Amadou Barry, Modibo Diarra, Amadou Tapily, Samba Coumare, Ismaila Thera, Frederic Nikiema, R. Serge Yerbanga, Rosemonde M. Guissou, Halidou Tinto, Alassane Dicko, Daniel Chandramohan, Brian Greenwood, Jean Bosco Ouedraogo   +18 more
doaj   +1 more source

Quantitative and Clinical Pharmacology Perspectives on Next‐Generation Malaria Prevention Using Vaccines and Long‐Acting Monoclonal Antibodies

Clinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Malaria remains a significant global health burden, particularly among pediatric populations in endemic regions. Recent advances in preventive interventions highlight the complementary roles of vaccines and long‐acting monoclonal antibodies (mAbs) in reducing infection risk.
Sabiha R. Mim, Leonardo C. Xavier, Francine J. Azeredo, Sihem Ait‐Oudhia   +3 more
wiley   +1 more source

Trends in uncomplicated and severe malaria following seasonal malaria chemoprevention administration in Nouna, Burkina Faso: a quasi-experimental pre-post study

Malaria Journal
Background While Seasonal Malaria Chemoprevention (SMC) has been adopted as a malaria control strategy in regions with seasonal transmission, continued monitoring and evaluation of its effectiveness across diverse ecological, epidemiological, and ...
Elisabeth A. Gebreegziabher, Mamadou Ouattara, Mamadou Bountogo, Boubacar Coulibaly, Valentin Boudo, Thierry Ouedraogo, Elodie Lebas, Huiyu Hu, David V. Glidden, Benjamin F. Arnold, Thomas M. Lietman, Ali Sié, Catherine E. Oldenburg   +12 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

Journal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi, Carmen Scieuzo, Federica De Stefano, Luca Masucci, Patrizia Falabella   +4 more
wiley   +1 more source