Results 21 to 30 of about 686,514 (182)

The role of seasonal malaria chemoprevention in the effect of azithromycin on child mortality: A secondary analysis of the CHAT cluster randomized clinical trial. [PDF]

PLOS Glob Public Health
Data from the secondary analysis of the CHAT Cluster Randomized Clinical Trial, examining the role of Seasonal Malaria Chemoprevention (SMC) in the effect of Azithromycin on child ...
Gebreegziabher EA, Ouattara M, Bountogo M, Coulibaly B, Boudo V, Ouedraogo T, Lebas E, Hu H, O'Brien KS, Hsiang MS, Glidden DV, Arnold BF, Lietman TM, Sié A, Oldenburg CE.   +14 more
europepmc   +2 more sources

Systematic Review and Meta-Analysis of Seasonal Malaria Chemoprevention. [PDF]

Am J Trop Med Hyg
ABSTRACT. Seasonal malaria chemoprevention (SMC) for children under 5 years of age for up to four monthly cycles during malaria transmission season was recommended by the WHO in 2012 and has been implemented in 13 countries in the Sahel, reaching more than 30 million children annually.
Thwing J, Williamson J, Cavros I, Gutman JR.   +3 more
europepmc   +3 more sources

Evaluation of seasonal malaria chemoprevention implementation in the Upper East region of Northern Ghana. [PDF]

Malar J
Ghana adopted the WHO-recommended Seasonal Malaria Chemoprevention (SMC) in 2016 following a pilot study as a vital strategy for malaria control. SMC is the intermittent administration of a preventive and curative dose of anti-malarial medicine (Sulfadoxine-Pyrimetamine + Amodiaquine) during four months of the malaria season.
Ayamba EY, Dzotsi EK, Dormechele W, Ansah NA, Bangre O, Nyuzaghl JA, Abilba SA, Boakye-Boateng SK, Ansah PO.   +8 more
europepmc   +4 more sources

Emergence of Plasmodium falciparum pfdhps A581G mutation in Southern Senegal under Seasonal Malaria Chemoprevention pressure, 2020-2023 [PDF]

Communications Medicine
Background: Malaria prevention in Senegal includes the use of Seasonal Malaria Chemoprevention with sulfadoxine-pyrimethamine plus amodiaquine. Prolonged use of sulfadoxine-pyrimethamine, however, can select for mutations in the Plasmodium falciparum ...
Mamadou Alpha Diallo, Abdoulaye Tine, Djiby Sow, Aita Sene, Amy Gaye, Yaye D. Ndiaye, Jules Gomis, Baba Dieye, Awa B. Deme, Mamadou S. Yade, Bassirou Ngom, Mamane N. Garba, Ibrahima M. Ndiaye, Khadim Diongue, Aida Sadikh Badiane, Mame Cheikh Seck, Mouhamadou Ndiaye, Daouda Ndiaye   +17 more
doaj   +2 more sources

Impact of seasonal malaria chemoprevention timing on clinical malaria incidence dynamics in the Kedougou region, Senegal. [PDF]

PLOS Glob Public Health
Abstract Seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine is recommended by the World Health Organization since 2012 for clinical malaria prevention in children in the Sahelian region of Africa. In Senegal, SMC implementation began in 2013 and is given to children under 10 years old. This study aimed
Kazanga B, Ba EH, Legendre E, Cissoko M, Fleury L, Bérard L, Diop A, Sokhna C, Danfakha F, Sagara I, Ndiaye JL, Gaudart J, Landier J.   +12 more
europepmc   +5 more sources

Measuring the impact of seasonal malaria chemoprevention as part of routine malaria control in Kita, Mali

Malaria Journal, 2017
Seasonal malaria chemoprevention (SMC) is a new strategy recommended by WHO in areas of highly seasonal transmission in March 2012. Although randomized controlled trials (RCTs) have shown SMC to be highly effective, evidence and experience from routine implementation of SMC are limited.A non-randomized pragmatic trial with pre-post design was used ...
Diawara, Fatou, Steinhardt, Laura, Mahamar, Almahamoudou, Traore, Tiangoua, Koné, Daouda, Diawara, Halimatou, Kamate, Beh, Kone, Diakalia, Diallo, Mouctar, Sadou, Aboubacar, Mihigo, Jules, Sagara, Issaka, Djimde, Abdoulaye, Eckert, Erin, Dicko, Alassane   +14 more
openaire   +5 more sources

Indirect benefits of seasonal malaria chemoprevention for non-malarial pediatric infections and routine antibiotic use in real-world programmatic settings: a pre-post study using positive and negative controls. [PDF]

BMC Infect Dis
This repository contains formatted, de-identified data for the paper: Indirect benefits of seasonal malaria chemoprevention for non-malarial pediatric infections and routine antibiotic use in real-world programmatic settings: a pre-post study using ...
Gebreegziabher EA, Ouattara M, Bountogo M, Coulibaly B, Boudo V, Ouedraogo T, Lebas E, Hu H, O'Brien KS, Hsiang MS, Glidden DV, Arnold BF, Lietman TM, Sié A, Oldenburg CE.   +14 more
europepmc   +2 more sources

Spontaneous adverse drug reaction reporting during the seasonal malaria chemoprevention campaign in 2022

Bulletin of the National Research Centre, 2023
Background Seasonal administration of antimalaria drug, sulphadoxine/pyrimethamine plus amodiaquine to children 3–59 months is a malaria preventive intervention used for the reduction of childhood malaria morbidity and mortality in area with highly ...
Kunle Rotimi, Babatunde Fagbemi, Taiwo Ibinaiye, Jimmy Aiden, Victor Gabriel, Chrysantus Dabes, Tapshak Kyeshir, Daniel Oguche, Omolola Obayemi, Aminu Biambo, Andrew Okwulu, Adaeze Aidenagbon   +11 more
doaj   +1 more source

Malaria chemoprevention and drug resistance: a review of the literature and policy implications

Malaria Journal, 2022
Chemoprevention strategies reduce malaria disease and death, but the efficacy of anti-malarial drugs used for chemoprevention is perennially threatened by drug resistance.
Christopher V. Plowe
doaj   +1 more source

A hybrid effectiveness-implementation study protocol to assess the effectiveness and chemoprevention efficacy of implementing seasonal malaria chemoprevention in five districts in Karamoja region, Uganda [version 2; peer review: 1 approved, 2 approved with reservations]

Gates Open Research, 2023
Background The World Health Organization (WHO) recommends seasonal malaria chemoprevention (SMC) with sulfadoxine-pyrimethamine and amodiaquine (SPAQ) for children aged 3 to 59 months, living in areas where malaria transmission is highly seasonal ...
Craig Bonnington, Sol Richardson, Godfrey Magumba, Christian Rassi, Jane Nabakooza, Denis Rubahika, Anthony Nuwa, James Tibenderana, Jimmy Opigo, Jane Achan, Richard Kajubi, Kevin Baker, Jennifer Ainsworth   +12 more
doaj   +1 more source