Results 81 to 90 of about 34,551 (199)

Conformational Changes of the Clamp of the Protein Translocation ATPase SecA [PDF]

Journal of Molecular Biology, 2015
Post-translational protein translocation across the bacterial plasma membrane is mediated by the interplay of the SecA ATPase and the protein-conducting SecY channel. SecA consists of several domains, including two nucleotide-binding domains (NBD1 and NBD2), a polypeptide cross-linking domain (PPXD), a helical scaffold domain (HSD), and a helical wing ...
Yu, Chen, Benedikt W, Bauer, Tom A, Rapoport, James C, Gumbart   +3 more
openaire   +2 more sources

Evaluation of tissue response of experimental calcium silicate‐based endodontic sealers: An in vivo study

European Journal of Oral Sciences, EarlyView.
Abstract The aim of this study was to evaluate whether the experimental sealers, composed of tricalcium silicate (CaSi) and CaSi supplemented with calcium hypochlorite (CaSi‐H), stimulate tissue repair. The tissue response of experimental materials was compared with commercially available materials Bio‐C sealer (BC sealer) and BioRoot (BROOT ...
Evelin Carine Alves Silva, Lucas de Andrade Rodrigues, Estela Sasso‐Cerri, Mário Tanomaru‐Filho, Juliane Maria Guerreiro‐Tanomaru, Paulo Sérgio Cerri   +5 more
wiley   +1 more source

Influence of the dry and rainy seasons upon plasma seminal (SDS-PAGE) and characteristics of the ejaculate from bulls Bos taurus indicus
Influência das estações seca e chuvosa no plasma seminal (SDS-PAGE) e características do ejaculado de touros Bos taurus indicus

Semina: Ciências Agrárias, 2011
Disruptions in sperm production include decreased sperm motility and increased of abnormal sperm. Seminal plasma appears to exert important effects on sperm function.
Andrea Marisol Novoa Castillo, Marcelo George Mungai Chacur, Luciana Machado Guaberto   +2 more
doaj   +1 more source

Metabolic Health Phenotypes Among Middle‐ to Older‐Aged Adults Living With and Without Obesity: Relationships With Hepatic Health Indicators

Hepatology Research, EarlyView.
We examined liver health indicators among obese and nonobese metabolic health phenotypes. In fully adjusted models, higher fatty liver index (FLI) scores and liver enzyme concentrations of gamma‐glutamyl transferase (GGT) and alanine aminotransferase (ALT) were associated with lower likelihood of metabolically healthy obese (MHO) and nonobese (MHNO ...
Grainne Dolan, Seán R. Millar, Ivan J. Perry, Catherine M. Phillips   +3 more
wiley   +1 more source

Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii [PDF]

, 2015
ACKNOWLEDGMENTS We acknowledge support from BBSRC grant no. BB/L009951/1, from the Scottish government Food, Land and People program, and from the Society for Applied Microbiology. E.A.B. is supported by a grant (no.
Bayer, Edward A., Dassa, Bareket, David, Ben, Duncan, Sylvia H, Flint, Harry J, Henrissat, Bernard, Juge, Natahlie, Koropatkin, Nicole M, Laverde Gomez, Jenny, Louis, Petra Gisela Helen, Sheridan, Paul O, Ze, Xiaolei   +11 more
core   +4 more sources

The Bacterial ATPase SecA Functions as a Monomer in Protein Translocation [PDF]

Journal of Biological Chemistry, 2005
The ATPase SecA drives the post-translational translocation of proteins through the SecY channel in the bacterial inner membrane. SecA is a dimer that can dissociate into monomers under certain conditions. To address the functional importance of the monomeric state, we generated an Escherichia coli SecA mutant that is almost completely monomeric (>99%),
Eran, Or, Dana, Boyd, Stéphanie, Gon, Jonathan, Beckwith, Tom, Rapoport   +4 more
openaire   +2 more sources

Evaluating the Effect of a Sleep Prehabilitation Intervention in Patients Awaiting Elective Surgery: Protocol for a Single‐Blind Randomised Trial

Journal of Sleep Research, EarlyView.
ABSTRACT Adequate sleep health is critical for surgical recovery. Disrupted sleep can impede wound healing and cognitive performance and contribute to poor surgical outcomes. Preoperative intervention aimed at improving surgical outcomes is often referred to as prehabilitation and commonly uses exercise, nutrition or psychological intervention.
Daniel Sibley, Ian Randall, S. Nicole Culos‐Reed, P. Maxwell Slepian, Mandeep Singh, Daniel Santa Mina   +5 more
wiley   +1 more source

Determination of the intracellular concentration of the export chaperone SecB in Escherichia coli. [PDF]

PLoS ONE, 2017
SecB, a small tetrameric chaperone in Escherichia coli, plays a crucial role during protein export via the general secretory pathway by binding precursor polypeptides in a nonnative conformation and passing them to SecA, the ATPase of the translocon. The
Bahar T Findik, Linda L Randall
doaj   +1 more source

Membrane protein insertion and assembly by the bacterial holo-translocon SecYEG-SecDF-YajC-YidC [PDF]

, 2016
Protein secretion and membrane insertion occur through the ubiquitous Sec machinery. In this system, insertion involves the targeting of translating ribosomes via the signal recognition particle and its cognate receptor to the SecY (bacteria and archaea)/
Alvira-de-Celis, Sara, Berger, Imre, Collinson, Ian, Dafforn, Timothy, Deckers-Hebestreit, Gabriele, Komar, Joanna, Lee, S, Martin, Remy, Nijeholtb, Jelger A. Lycklama A., Schaffitzel, Christiane, Schulze, Ryan   +10 more
core   +4 more sources

Global Co-ordination of Protein Translocation by the SecA IRA1 Switch [PDF]

Journal of Biological Chemistry, 2004
SecA, the dimeric ATPase subunit of protein translocase, contains a DEAD helicase catalytic core that binds to a regulatory C-terminal domain. We now demonstrate that IRA1, a conserved helix-loop-helix structure in the C-domain, controls C-domain conformation through direct interdomain contacts.
Eleftheria, Vrontou, Spyridoula, Karamanou, Catherine, Baud, Giorgos, Sianidis, Anastassios, Economou   +4 more
openaire   +2 more sources