Results 21 to 30 of about 97,166 (237)
Preconditioned cues have no value
eLife, 2017 Sensory preconditioning has been used to implicate midbrain dopamine in model-based learning, contradicting the view that dopamine transients reflect model-free value.
Melissa J Sharpe +2 more
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Individual variability in behavioral flexibility predicts sign-tracking tendency
Frontiers in Behavioral Neuroscience, 2015 Sign-tracking rats show heightened sensitivity to food- and drug-associated cues, which serve as strong incentives for driving reward seeking. We hypothesized that this enhanced incentive drive is accompanied by an inflexibility when incentive value ...
Helen M Nasser +5 more
doaj +1 more source
Second-order conditioning of fear [PDF]
Psychonomic Science, 1964 First-order classical fear conditioning trials (tone paired with shock) were interspersed with second-order classical conditioning trials (light paired with the tone). Subsequently, Ss (rats) learned to escape the light by jumping a hurdle. Comparison of this performance with that of two control groups allowed the conclusion that fear was conditioned ...
Dorothy E. McAllister +1 more
openaire +1 more source
Energy Reports, 2023 In recent years, the accelerated penetration of renewable energy hinders the flexible adjustment of power systems. Customer directrix load (CDL)-based demand response (DR) unlocks the potential flexibilities of inverter air conditioning in industrial or ...
Lingling Zhu +6 more
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BMC Biology, 2009 Background In insect classical conditioning, octopamine (the invertebrate counterpart of noradrenaline) or dopamine has been suggested to mediate reinforcing properties of appetitive or aversive unconditioned stimulus, respectively. However, the roles of
Hatano Ai +5 more
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Energies, 2013 This paper proposes a second-order harmonic reduction technique using a proportional-resonant (PR) controller for a photovoltaic (PV) power conditioning system (PCS).
Hae-Gwang Jeong +2 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
FEBS Letters, EarlyView.The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source