Results 41 to 50 of about 97,166 (237)

Second order optimality conditions for differentiable multiobjective problems [PDF]

RAIRO - Operations Research, 2000
Summary: A secood order optimality condition for multiobjective optimization with a set constraints is developed; this condition is expressed as the impossibility of nonhomogeneous linear systems. When the constraint is given in terms of inequalities and equalities, it can be turned into a John type multipliers rule, using a nonhomogeneous Motzkin ...
CASTELLANI, MARCO, BIGI G.
openaire   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Bifurcation Theorems via Second-Order Optimality Conditions

Journal of Mathematical Analysis and Applications, 2001
The authors prove new bifurcation existence theorems based on the theory of second-order optimality conditions for abnormal constrained optimization problems [the first author, Optimality conditions. Abnormal and degenerate problems. Dordrecht: Kluwer Academic Publishers (2000; Zbl 0987.49001)]. Remarks: In the list of references the following articles
Arutyunov A.V., Izmailov A.F.
openaire   +3 more sources

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Second order systems with nonlinear boundary conditions [PDF]

Proceedings of the American Mathematical Society, 1977
Some existence theorems are established for nonlinear second order systems with nonlinear two point boundary conditions. The system is assumed to satisfy certain differential inequality conditions at the boundary of a region.
openaire   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Bumblebee social learning outcomes correlate with their flower-facing behaviour

Animal Cognition
Previous studies suggest that social learning in bumblebees can occur through second-order conditioning, with conspecifics functioning as first-order reinforcers.
Yuyi Lu, Zhenwei Zhuo, Mark Roper, Lars Chittka, Cwyn Solvi, Fei Peng, Ying Zhou   +6 more
doaj   +1 more source

Factorial Experiments of Soil Conditioning for Earth Pressure Balance Shield Tunnelling in Water-Rich Gravel Sand and Conditioning Effects’ Prediction Based on Particle Swarm Optimization–Relevance Vector Machine Algorithm

Buildings
The high permeability of gravel sand increases the risk of water spewing from the screw conveyor during earth pressure balance (EPB) shield tunnelling.
Xingzhong Nong, Wenfeng Bai, Jiandang Chen, Lihui Zhang   +3 more
doaj   +1 more source

Behavioral and electrodermal data on implicit nocebo conditioning using supraliminally presented visual stimuli

Data in Brief, 2019
This article contains intensity and aversiveness ratings of electrical stimuli and data on electrodermal activity (skin conductance level and skin conductance response) during an implicit conditioning procedure.
Anne-Kathrin Bräscher, Michael Witthöft   +1 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source