Results 51 to 60 of about 100,213 (248)

Associative structure of second-order conditioning in humans [PDF]

Learning & Behavior, 2017
Second-order conditioning (SOC; i.e., conditioned responding to S2 as a result of S1-US pairings followed by S2-S1 pairings) is generally explained by either a direct S2→US association or by an associative chain (i.e., S2→S1→US). Previous research found that differences in responses to S2 after S1 was extinguished often depended on the nature of the S2-
Craddock, Paul, Wasserman, Jessica S., Polack, Cody W., Kosinski, Thierry, Renaux, Charlotte, Miller, Ralph R.   +5 more
openaire   +3 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Second-order threat conditioning in the amygdala-posterior piriform cortex network

Communications Biology
Fear, while crucial for survival, is a component of a myriad of psychiatric illnesses in its extreme. Persistent fear memories can form through processes such as second-order conditioning (SOC), during which a second-order conditioned stimulus (CS2 ...
Tayebeh Sepahvand, Tian Qin, Zia Hasan, Kyron D. Power, Samantha J. Carew, Negar Nazari, Alyssa M. Janes, Ali Salman, Yue Xia, Touati Benoukraf, Qi Yuan   +10 more
doaj   +1 more source

Mechanism and Parameter Optimization of Fenton's Reagent Integrated with Surfactant Pretreatment to Improve Sludge Dewaterability. [PDF]

PLoS ONE, 2017
Sludge dewatering can effectively reduce the volume and mass of sludge for subsequent treatment and disposal. The work validated the potential of Fenton's reagent combined with dodecyl dimethyl benzyl ammonium chloride (DDBAC) in improving sludge ...
Yi Xing, Zhiqiang Wang, Chen Hong, Qiang Yang, Lihui Feng, Mengmeng Jia, Yifei Li   +6 more
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Parallel olfactory processing in the honey bee brain: odor learning and generalization under selective lesion of a projection neuron tract

Frontiers in Integrative Neuroscience, 2016
The function of parallel neural processing is a fundamental problem in Neuroscience, as it is found across sensory modalities and evolutionary lineages, from insects to humans.
Julie eCarcaud, Julie eCarcaud, Martin eGiurfa, Jean-Christophe eSandoz   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Bumblebee social learning outcomes correlate with their flower-facing behaviour

Animal Cognition
Previous studies suggest that social learning in bumblebees can occur through second-order conditioning, with conspecifics functioning as first-order reinforcers.
Yuyi Lu, Zhenwei Zhuo, Mark Roper, Lars Chittka, Cwyn Solvi, Fei Peng, Ying Zhou   +6 more
doaj   +1 more source

Factorial Experiments of Soil Conditioning for Earth Pressure Balance Shield Tunnelling in Water-Rich Gravel Sand and Conditioning Effects’ Prediction Based on Particle Swarm Optimization–Relevance Vector Machine Algorithm

Buildings
The high permeability of gravel sand increases the risk of water spewing from the screw conveyor during earth pressure balance (EPB) shield tunnelling.
Xingzhong Nong, Wenfeng Bai, Jiandang Chen, Lihui Zhang   +3 more
doaj   +1 more source