Results 61 to 70 of about 10,869 (265)

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Saddle Points of Partial Augmented Lagrangian Functions

Mathematical and Computational Applications
In this paper, we study a class of optimization problems with separable constraint structures, characterized by a combination of convex and nonconvex constraints.
Longfei Huang, Jingyong Tang, Yutian Wang, Jinchuan Zhou   +3 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Boundary value problems for systems of second-order functional differential equations

Electronic Journal of Qualitative Theory of Differential Equations, 2000
Systems of second-order functional differential equations $(x'(t)+L(x)(t))'=F(x)(t)$ together with nonlinear functional boundary conditions are considered. Here $L:C^1([0,T];\mathbb{R}^n) \rightarrow C^0([0,T];\mathbb{R}^n)$ and $F:C^1([0,T];\mathbb{R}^n)
S. Stanek
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Second order optimality conditions in nonsmooth unconstrained optimization

, 1998
Summary: Second order necessary and sufficient conditions are given for a nonsmooth function \(f\) defined in a Banach space to attain a minimum at a point in the interior of its domain. At the beginning sufficient conditions in terms of Riemann type derivatives are introduced.
IVANOV, IVAN GINCHEV, GUERRAGGIO, ANGELO
openaire   +3 more sources

Second-order optimality conditions in nonsmooth vector optimization

Control and Cybernetics, 2023
Abstract In this paper, we introduce new classes of nonsmooth second-order cone-convex functions and respective generalizations in terms of first and second-order directional derivative. These classes encapsulate several already existing classes of cone-convex functions and their weaker variants.
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Sufficient Efficiency Conditions for Vector Ratio Problem on the Second-Order Jet Bundle

Abstract and Applied Analysis, 2012
Motivated by its possible applications in mechanics and mechanical engineering, in our previous published work (Pitea and Postolache, 2011), we initiated an optimization theory for the second-order jet bundle. We considered the problem of minimization of
Ariana Pitea
doaj   +1 more source