Results 71 to 80 of about 20,565,365 (293)

First order optimality condition for constrained set-valued optimization [PDF]

open access: yes
A constrained optimization problem with set-valued data is considered. Different kind of solutions are defined for such a problem. We recall weak minimizer, efficient minimizer and proper minimizer.
Rocca Matteo   +2 more
core  

First and second order optimality conditions in set optimization

open access: yes, 2006
By using the second order asymptotic cone two epiderivatives for setvalued maps are proposed and employed to obtain second order necessary optimality conditions in set optimization.
Jadamba, B.   +2 more
core   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Second-order conditions for spatio-temporally sparse optimal control via second subderivatives [PDF]

open access: yesJournal of Nonsmooth Analysis and Optimization
We address second-order optimality conditions for optimal control problems involving sparsity functionals which induce spatio-temporal sparsity patterns. We employ the notion of (weak) second subderivatives.
Nicolas Borchard, Gerd Wachsmuth
doaj   +1 more source

Second-order mollified derivatives and optimization [PDF]

open access: yes
The class of strongly semicontinuous functions is considered. For these functions the notion of mollified derivatives, introduced by Ermoliev, Norkin and Wets, is extended to the second order.
Rocca Matteo   +2 more
core  

Second order necessary conditions of optimality for impulsive control systems

open access: yes, 2020
Second order conditions of optimality are presented for an impulsive control problem. The general approach defined in order to derive informative optimality conditions allows the consideration of abnormal problems without additional assumptions.
Arutyunov A., Pereira F., Jacimović V.
core  

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Second order optimality conditions for infinite programs [PDF]

open access: yes, 1989
The paper deals with the minimization problem of a marginal function over a subset C of a space X. Unlike the existing papers, X is not assumed to be a finitedimensional space and C is a geometric constraint which may not coincide with X.
Sach, Pham H., Oettli, Werner
core   +1 more source

Second-Order Subdifferential Optimality Conditions in Nonsmooth Optimization [PDF]

open access: yes, 2023
The paper is devoted to deriving novel second-order necessary and sufficient optimality conditions for local minimizers in rather general classes of nonsmooth unconstrained and constrained optimization problems in finite-dimensional spaces.
Khanh, Pham Duy   +3 more
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

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