Results 71 to 80 of about 4,898,023 (356)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Additional English Language Materials and the Learners with Disabilities’ Learning Outcomes in Malaysia: A Correlational Study

Asian Journal of Assessment in Teaching and Learning
This study explores the relationship between the use of additional instructional materials—including technological tools, pedagogical resources, and supplementary learning aids—by special education teachers and the classroom performance of learners with
Muhammad Azwan Basaruddin, Hema Rosheny Mustafa   +1 more
doaj   +1 more source

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

Designing an effective digital learning environment for teaching English through literature: the learning experience of Bulgarian students

Je-LKS: Journal of E-Learning and Knowledge Society, 2019
The present article will focus on motivation in foreign language learning, digital technologies and creating an effective digital learning environment for supporting the process of learning and reaching desired outcomes.
Maria Metodieva Genova
doaj   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

FEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

The influence of the Pinyin and Zhuyin writing systems on the acquisition of Mandarin word forms by native English speakers

Frontiers in Psychology, 2016
The role of written input in second language (L2) phonological and lexical acquisition has received increased attention in recent years. Here we investigated the influence of two factors that may moderate the influence of orthography on L2 word form ...
Rachel eHayes-Harb, Hui-wen eCheng
doaj   +1 more source

Language and Reading Progress of Young Deaf and Hard-of-Hearing Children. [PDF]

, 2020
We examined the language and reading progress of 336 young DHH children in kindergarten, first and second grades. Trained assessors tested children's language, reading, and spoken and fingerspelled phonological awareness in the fall and spring of the ...
Antia, Shirin D, Branum-Martin, Lee, Connor, Carol M, Easterbrooks, Susan, Lederberg, Amy R, Schick, Brenda, Webb, Mi-Young   +6 more
core  

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Instant messaging clients - Relaxed, free & enjoyable English learning and training tools [PDF]

, 2007
In a demanding world of using English as a second language, computer technology and the internet are being dominantly used as they provide an incredible boost to language learning environment.
Abu Bakar, Hanif Suhairi, Mahadi, Rozilawati   +1 more
core