Results 81 to 90 of about 10,492,879 (293)

Validation in Second Language Classroom Research: The Role of Observation [PDF]

open access: yes, 1988
The purpose of this paper is to explore more precisely how observational analyses of classroom interaction can be validated, and further, how the validation of claims about instructional variables (such as the effectiveness of programs, teaching methods,
Chaudron, Craig
core   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Designing an effective digital learning environment for teaching English through literature: the learning experience of Bulgarian students

open access: yesJe-LKS: Journal of E-Learning and Knowledge Society, 2019
The present article will focus on motivation in foreign language learning, digital technologies and creating an effective digital learning environment for supporting the process of learning and reaching desired outcomes.
Maria Metodieva Genova
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

The language socialization paradigm for SLA: What's in it for you? [PDF]

open access: yes, 2002
Watson-Gegeo (2001) tells us that we are “at the beginning of a paradigm shift in the human and social sciences” that is “fundamentally transforming second language acquisition (SLA) and educational theory and research” (p. 1).
Gregg, Kevin R.
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

A Descriptive Study: Factors Affecting the Pronunciation of English Language (L2)

open access: yesJournal of Communication and Cultural Trends, 2019
Acquiring correct second language pronunciation is an indispensable part of the language learning process. It plays a substantial role in enhancing the communicative competence and performance of second language learners. The learning of pronunciation is
Tania Ali Khan
doaj   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Universals of Word Formation Processes: Noun Incorporated in the Acquisition of Sāmoan as a Second Language [PDF]

open access: yes, 1993
Studies of sccond language syntactic acquisition (e.g., Gass 1979; Flynn 1991; White 1989) have been motivated by research into language universals within both typological (Creenberg 1966), and universal grammar (Chomsky 1981) frameworks.
Robinson, Peter J.
core   +1 more source

Enhancing Medical Students’ Communicative Skills in a 3D Virtual World

open access: yesEducational Technology & Society, 2019
This study explores the effects of how collaborating in a virtual world (VW) enhanced learners’ healthcare professional-patient communicative skills, including physician-patient and inter-professional communication in medical discourse.
Yi-Ju Ariel Wu   +3 more
doaj  

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