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[Treatment of autoimmune hepatitis-First-line, second-line and third-line treatment].
Innere Medizin (Heidelberg, Germany)Autoimmune hepatitis (AIH) is a rare autoimmune inflammation of the liver mostly with a chronic course, which can also be acutely manifested up to acute liver failure. It affects women 3-4 times more frequently than men and can be diagnosed in all age groups. In one third of the patients a liver cirrhosis is present at the time of diagnosis.
Richard, Taubert, Bastian, Engel
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[Second line treatments of cancers of the ovary].
La Revue du praticien, 1997Ovarian adenocarcinomas are among the most chemosensitive tumors. Platinum derivatives are the most efficient agents. The role of the second-line therapy is either to treat the relapse (salvage therapy), or to prevent it (consolidation therapy). The most active agents in the salvage setting are new molecules: taxoids, vinorelbin, topotecan.
J M, Extra, P H, Cottu
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Advancements in second-line treatment research for hepatocellular carcinoma
Clinical and Translational OncologyHepatocellular carcinoma (HCC) is one of the most common malignant tumors, characterized by high incidence and mortality rates. Due to its insidious onset, most patients are diagnosed at an advanced stage, often missing the opportunity for surgical resection. Consequently, systemic treatments play a pivotal role.
Ruirui Sun +4 more
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Comparative effectiveness of second‐line treatments for epileptic spasms
EpilepsiaAbstract Objective This study was undertaken to evaluate the response to second treatments for infantile epileptic spasms syndrome (IESS). Methods Infants aged 2–24 months with IESS were prospectively enrolled in the ...
Kristen Barbour +21 more
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[Second-line treatments for Parkinson's disease].
La Revue du praticienFollowing an initial phase characterized by a good response to dopaminergic therapies, Parkinson's disease progresses toward a stage marked by motor complications-notably motor fluctuations and dyskinesias. When the optimization of oral therapy proves insufficient, the use of second-line treatments must be considered.
Guillaume, Carey, Luc, Defebvre
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Treatment-Free Remission After Second-Line Nilotinib Treatment
Annals of Internal Medicine, 2018François-Xavier, Mahon +1 more
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An Approximate Line Attractor in the Hypothalamus Encodes an Aggressive State
Cell, 2023Aditya Nair +2 more
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Preserving Primary Care: The Front Line in the War Against Cancer
Ca-A Cancer Journal for Clinicians, 2007Richard C Wender
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