Results 11 to 20 of about 539,249 (323)

Clp is a “busy” transcription factor in the bacterial warrior, Lysobacter enzymogenes

open access: yesComputational and Structural Biotechnology Journal, 2021
Cyclic AMP receptor protein (CRP) is a well-characterized group of global transcription factors in bacteria. They are known to regulate numerous cellular processes by binding DNA and/or cAMP (a ligand called bacterial second messenger) to control target ...
Kangwen Xu   +4 more
doaj   +1 more source

Essential Functions of the Transcription Factor Npas4 in Neural Circuit Development, Plasticity, and Diseases

open access: yesFrontiers in Neuroscience, 2020
Signaling from the synapse to nucleus is mediated by the integration and propagation of both membrane potential changes (postsynaptic potentials) and intracellular second messenger cascades.
Jian Fu   +3 more
doaj   +1 more source

Yin and Yang of Biofilm Formation and Cyclic di-GMP Signaling of the Gastrointestinal Pathogen Salmonella enterica Serovar Typhimurium

open access: yesJournal of Innate Immunity, 2021
Within the last 60 years, microbiological research has challenged many dogmas such as bacteria being unicellular microorganisms directed by nutrient sources; these investigations produced new dogmas such as cyclic diguanylate monophosphate (cyclic di-GMP)
Agaristi Lamprokostopoulou, Ute Römling
doaj   +1 more source

To be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger?

open access: yesBiological Research, 2004
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent activator of intracellular Ca2+ release in several vertebrate and invertebrate systems.
EDUARDO NUNES CHINI
doaj   +1 more source

Spatial Turing-type Pattern Formation in a Model of Signal Transduction Involving Membrane-based Receptors Coupled by G Proteins

open access: yesCancer Informatics, 2006
In this paper, a model of signaling pathways involving G proteins is investigated. The model incorporates reaction-diffusion mechanisms in which various reactants participate inside and on the extra-cellular surface membrane.
Chontita Rattanakul   +5 more
doaj   +2 more sources

Au naturale: use of biologically derived cyclic di-nucleotides for cancer immunotherapy

open access: yesOpen Biology, 2021
Cyclic di-nucleotides (CDNs) are widespread second messenger signalling molecules that regulate fundamental biological processes across the tree of life.
Christopher M. Waters
doaj   +1 more source

Heterogeneity in Surface Sensing Suggests a Division of Labor in Pseudomonas aeruginosa Populations [PDF]

open access: yes, 2019
The second messenger signaling molecule cyclic diguanylate monophosphate (c-di-GMP) drives the transition between planktonic and biofilm growth in many bacterial species.
Armbuster, Catherine R.   +12 more
core   +2 more sources

Adenylyl cyclase: mediator of the intraocular pressure response to adrenergic agents : experimental studies with a phosphodiesterase-inhibitor [PDF]

open access: yes, 1992
This study was designed to gain more knowledge about the role of the AC/cyclic AMP second messenger system in the reduction of IOP, particularly in response to adrenergic agents. The principle approach was to augment pharmacologically the AC/cAMP signals
Busch, M.J.W.M. (Michiel)
core   +10 more sources

Zinc: A small molecule with a big impact on sperm function. [PDF]

open access: yesPLoS Biology, 2018
Zinc is an essential mineral, but our understanding of its uses in the body is limited. Capitalizing on approaches available in the model system Caenorhabditis elegans, Zhao and colleagues show that zinc transduces a signal that induces sperm to become ...
Diana S Chu
doaj   +1 more source

The virulence factor regulator and quorum sensing regulate the type I-F CRISPR-Cas mediated horizontal gene transfer in Pseudomonas aeruginosa

open access: yesFrontiers in Microbiology, 2022
Pseudomonas aeruginosa is capable of thriving in diverse environments due to its network of regulatory components for effective response to stress factors.
Stephen Dela Ahator   +5 more
doaj   +1 more source

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