Results 181 to 190 of about 37,344 (282)
OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta +4 more
wiley +1 more source
All-trans retinoic acid modulates proliferation and apoptosis of secondary hair follicle-dermal papilla cells in cashmere goats via the TGF-<i>β</i>2/Smad2/3 pathway. [PDF]
Gao Y +14 more
europepmc +1 more source
‘Outside‐in’ expression of Fz6 across multiple layers of mouse embryo epidermis is connected to Fz6 asymmetry in the basal layer plane. Fz6 loss‐of‐function correlated with failure to: coordinate axial bias of cell long axis orientation across epidermal layers, switch axial cell long axis orientation during suprabasal layer development and establish ...
C. J. Formstone
wiley +1 more source
Periodontal Architecture in Ectodermal Dysplasia: An Observational Clinical and Histological Study
ABSTRACT Objective To investigate gingival and periodontal characteristics in Ectodermal dysplasia (ED), focusing on soft‐tissue phenotype, anatomical variations, and periodontal architecture. Materials and Methods Observational clinical study of 11 individuals (16–30 years) with confirmed clinical or genetic ED diagnosis.
Marco Montevecchi +5 more
wiley +1 more source
ABSTRACT Background Dermatologic conditions are a significant reason for pediatric hospitalizations in the United States. A prior analysis of the 2012 Kids' Inpatient Database (KID) established a national benchmark for this burden, but changes in medical coding, healthcare delivery, and demographics necessitate an updated assessment.
Shiv Patel +3 more
wiley +1 more source
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson +6 more
wiley +1 more source
Abstract Introduction Forest fragmentation and defaunation are major drivers of biodiversity loss in the Atlantic Forest of Brazil, where 70–90% of tree species depend on animal‐mediated seed dispersal. Reintroduction of large frugivores, such as cracids, is being used to restore species populations and lost ecological functions.
Maria P. M. X. Rufino +9 more
wiley +1 more source
Screening and expression validation of key proteins for secondary hair follicle growth in cashmere goats based on iTRAQ quantitative proteomics technology. [PDF]
Chang J +8 more
europepmc +1 more source

