Results 71 to 80 of about 3,005,072 (284)

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Inebilizumab in AQP4‐Seropositive NMOSD: One‐Year Follow‐Up From a Multicenter, Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Real‐world evidence on inebilizumab among neuromyelitis optica spectrum disorder (NMOSD) patients is lacking. This study assessed inebilizumab among Chinese patients with aquaporin 4 autoantibody (AQP4‐IgG)‐seropositive NMOSD in a real‐world setting.
Mengcui Gui, Jiayang Zhan, Wei Li, Tao Jin, Dan He, Daishi Tian, Zhijun Li, Jing Lin, Yue Li, Hongyu Zhou, Bitao Bu   +10 more
wiley   +1 more source

Secondary immunodeficiencies [PDF]

Annals of Allergy, Asthma & Immunology, 2021
Karen S. Tuano, Neha Seth, Javier Chinen
openaire   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

PECULIARITIES OF ACUTE RESPIRATORY DISEASES IN PATIENTS WITH ATOPY

Архивъ внутренней медицины, 2015
In the work identified clinical and immunological characteristics of the course of ARVI patients with atopy and assessed the clinical efficacy of transfer factor in patients with severe immune deficiency.
L. O. Ponezheva, Zh. B. Ponezheva, A. N. Kupchenko   +2 more
doaj   +1 more source

Attomolar Detection of HIV‐1 With Label‐Free RCA‐rCRISPR on Smartphone

Advanced Science, EarlyView.
A new diagnostic strategy integrating rolling circle amplification (RCA) with a plasmid reporter–based ratiometric CRISPR (rCRISPR) system was developed to detect unfragmented HIV genomes with single‐digit attomolar sensitivity. The method quantifies targets using the plasmid relaxation ratio and employs a smartphone‐based mini‐gel device to enable ...
Noor Mohammad, Anastasiia Steksova, Yuyang Tang, Leyao Huang, Alireza Velayati, Shengwei Zhang, Aditi Dey Poonam, Sina Jamalzadegan, Matthew Breen, Hongjie Chen, Mahsa Bagi, Guochun Jiang, Qingshan Wei   +12 more
wiley   +1 more source

HUMAN IMMUNODEFICIENCY VIRUS AND CANCER IN CHILDREN IN SOUTH AFRICA [PDF]

, 2012
Background. Infection with human immunodeficiency virus-1 (HIV) increases the incidence of certain cancers in adults. Much less is known about the impact of infection on the risk of cancer in children. Aim.
Stefan, Daniela Cristina
core   +3 more sources

Advanced disease and CD8+ TEMRA cells predict severe infections in multiple myeloma

Frontiers in Immunology
IntroductionInfections are a major cause of early morbidity and mortality in patients with multiple myeloma (MM) who are characterized by immunodeficiency secondary to disease.
Eva Tranter, David Busch, Clarissa Heck, Igor Wolfgang Blau, Axel Nogai, Phillip Schiele, Phillip Schiele, Christian Meisel, Christian Meisel, Christian Meisel, Lars Bullinger, Lars Bullinger, Lars Bullinger, Marco Frentsch, Marco Frentsch, Il-Kang Na, Il-Kang Na, Il-Kang Na, Il-Kang Na   +18 more
doaj   +1 more source

COVID-19 mortality in patients with immunodeficiency and its predictors: a systematic review

European Journal of Medical Research, 2022
Introduction Patients with immunodeficiency are usually more prone to worse outcomes of infectious diseases. However, there are some disagreements in the context of COVID-19, for example, in patients with human immunodeficiency virus (HIV).
SeyedAhmad SeyedAlinaghi, Amirali Karimi, Alireza Barzegary, Hengameh Mojdeganlou, Farzin Vahedi, Seyed Peyman Mirghaderi, Parnian Shobeiri, Maryam Ramezani, Parisa Yousefi Konjdar, Pegah Mirzapour, Marcarious M. Tantuoyir, Esmaeil Mehraeen, Omid Dadras, Fabricio Voltarelli   +13 more
doaj   +1 more source

Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific [PDF]

, 1992
Krämer A, Biggar RJ, Hampl H, et al. Immunologic markers of progression to acquired immunodeficiency syndrome are time-dependent and illness-specific. American Journal of Epidemiology.
Biggar, Robert J., Hampl, Hartmut, Fuchs, Dietmar, Krämer, Alexander ; https://orcid.org/, Goedert, James J., Friedman, Robert M., Wachter, Helmut   +6 more
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