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Innate Lymphoid Cells in Human Peripheral Blood and Secondary Lymphoid Organs
, 2017 openaire +2 more sources
Characterization of CCL21 expression in human secondary lymphoid organs and ectopic lymphoid tissues
, 2016 Bugatti, S +8 more
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Chemokines as organizers of primary and secondary lymphoid organs
Seminars in Immunology, 2003Lymphoid organs represent highly specialized tissues enabling the development and activation of B and T lymphocytes. Contact between lymphoid and parenchymal cells in bone marrow and thymus is a prerequisite for proper development of B and T cells, respectively, while secondary lymphoid organs, such as spleen and lymph nodes are the places where B and ...
Lars, Ohl +3 more
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Modeling immune reactivity in secondary lymphoid organs
Bulletin of Mathematical Biology, 1992Models of the dynamical interactions important in generating immune reactivity have generally assumed that the immune system is a single well-stirred compartment. Here we explicitly take into account the compartmentalized nature of the immune system and show that qualitative conclusions, such as the stability of the immune steady state, depend on ...
Perelson, Alan S., Weisbuch, Gérard
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Lymphocyte tracking and interactions in secondary lymphoid organs
Inflammation Research, 2007The induction of an adaptive immune response is an essential step in the generation of long-lasting, protective immunity to pathogens. Many studies over the last few decades have identified the cell populations involved in the generation of antigen-specific immunity and elucidated the role of many important molecules.
Brewer, J.M. +4 more
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Elucidating the functional anatomy of secondary lymphoid organs
Current Opinion in Immunology, 2004Functional anatomy offers an attempt to exploit anatomical information as a platform from which to decipher mechanistic details of complex or multistep immunological processes. Immune function depends on structural organization, therefore this approach contributes to a comprehensive understanding of the immune system.
Oliver, Pabst +3 more
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Cytokine regulation of secondary lymphoid organ development
Current Opinion in Immunology, 1998Lymphotoxin and tumor necrosis factor provide essential signals for the formation of secondary lymphoid tissue structures. Lymphotoxin in its membrane form (LT alpha 1 beta 2 heterotrimer) is required for the development of lymph nodes and Peyer's patches and supports the development of normal spleen structure.
D D, Chaplin, Y, Fu
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Artificial Engineering of Secondary Lymphoid Organs
2010Secondary lymphoid organs such as spleen and lymph nodes are highly organized immune structures essential for the initiation of immune responses. They display distinct B cell and T cell compartments associated with specific stromal follicular dendritic cells and fibroblastic reticular cells, respectively. Interweaved through the parenchyma is a conduit
Jonathan K H, Tan, Takeshi, Watanabe
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