Results 101 to 110 of about 219,209 (310)

Genomic and transcriptomic analyses reveal differential regulation of diverse terpenoid and polyketides secondary metabolites in Hericium erinaceus [PDF]

, 2017
Juan Chen, Xu Zeng, Yan Yang, Yong-Mei Xing, Qi Zhang, Jia Mei Li, Ke Ma, Hong Wei Liu, Shun Guo   +8 more
openalex   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Chemical defense among hydroids on pelagic Sargassum:predator deterrence and absorption of solar UV radiation by secondary metabolites

, 2021
John J. Stachowicz, Niels Lindquist
openalex   +1 more source

Icaritin Ameliorates Cisplatin‐Induced Mitochondrial Metabolic Dysfunction‐Associated Nephrotoxicity and Synergistically Potentiates Its Antitumor Efficacy

Advanced Science, EarlyView.
In this study, scRNA‐seq and chemoproteomics are integrated to characterize CDDP‐bound proteins at single‐cell resolution in tumor‐bearing mice. Additionally, the research demonstrates that ICA alleviates CDDP‐induced nephrotoxicity while enhancing its chemotherapeutic efficacy.
Piao Luo, Junhui Chen, Yehai An, Kun Meng, Wei Zhou, Wenhui Li, Jing Liu, Wentong Zhao, Weiyi He, Ting Cao, Jingnan Huang, Sha Feng, Shiguang Yang, Hongling Hu, Jiaxian Liao, Hengkai He, Mingjing Hao, Qian Zhang, Jigang Wang, Yue Gao   +19 more
wiley   +1 more source

Phenolic Compounds of Fresh Roots and Rhizomes of Garden Angelica Angelica Archangelica L.

International Journal of Secondary Metabolite, 2014
Because in the process of drying and storage of plant materials is a change of genuine compounds, we studied the content of phenolic compounds in freshly drawn angelica roots and rhizomes of the drug Angelica archangelica L. samples had been taken on the
R. M. BASHIROVA, А. G. MUSTAFIN1, E. G. GALKIN, F. F. ABDULLAEV   +3 more
doaj  

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Effect of Media on Gynogenesis Induction in Leek (allium ampeloprasum L.) Breeding Materials

International Journal of Secondary Metabolite, 2014
Leek (Allium ampeloprasum L.) is one of the economically important members of the genus Allium (family:Alliaceae). It is a self-compatible, outbreeding, tetraploid (2n=4X= 32) crop species that is very difficult to improve through traditional breeding ...
A. KASKA, F. CELEBI TOPRAK, A. R. ALAN   +2 more
doaj  

Epigenetic factors of the effect of UV-C and X-ray presowing seeds radiation exposure in Matricaria chamomilla L. genotypes

International Journal of Secondary Metabolite
In a series of experiments using both X-ray and UV-C radiation exposure a parallel study of several pharmacological characteristics of the Matricaria chamomilla L. genotype group was carried out.
Ludmila Hlushchenko, Vladyslav Zhuk, Alexandra Kravets, Daryna Sokolova   +3 more
doaj   +1 more source

Secondary Metabolites and Antioxidant Activity of Purwoceng (Pimpinella Pruatjan) Root Extracts from Various Hydroponic Planting Techniques [PDF]

, 2023
Irmanida Batubara, Shadila Fira Asoka, Eni Sumarni, Herry Suhardiyanto, Mohamad Solahudin, Slamet Widodo, Supriyanto Supriyanto, Eti Rohaeti, Yudiwanti Wahyu, Folkes E. Laumal, Erniati Erniati   +10 more
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source