Results 61 to 70 of about 676,672 (336)

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Spring Abundance, Migration Patterns and Damaging Period of Aleyrodes proletella in the Czech Republic

Agronomy
The cabbage whitefly has become an important pest on brassica vegetables in Central Europe. It does not destroy the affected plants, but the product becomes unmarketable, causing considerable economic losses.
Kamil Holý, Kateřina Kovaříková
doaj   +1 more source

Environmental Factors Regulate Plant Secondary Metabolites

Plants, 2023
Abiotic environmental stresses can alter plant metabolism, leading to inhibition or promotion of secondary metabolites. Although the crucial roles of these compounds in plant acclimation and defense are well known, their response to climate change is ...
Mirwais M. Qaderi, Ashley B. Martel, Courtney A. Strugnell   +2 more
doaj   +1 more source

Dual Induction of New Microbial Secondary Metabolites by Fungal Bacterial Co-cultivation [PDF]

, 2017
We thank the College of Physical Sciences, University of Aberdeen, for provision of infrastructure and facilities in the Marine Biodiscovery Centre.
Ebel, Rainer, Hassan, Hossam M., Jaspars, Marcel, Rateb, Mostafa E., Wakefield, Jennifer   +4 more
core   +2 more sources

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

Secondary metabolites and biodiversity of actinomycetes

Journal of Genetic Engineering and Biotechnology, 2021
Background The ability to produce microbial bioactive compounds makes actinobacteria one of the most explored microbes among prokaryotes. The secondary metabolites of actinobacteria are known for their role in various physiological, cellular, and ...
Manal Selim Mohamed Selim, Sayeda Abdelrazek Abdelhamid, Sahar Saleh Mohamed   +2 more
doaj   +1 more source

Secondary metabolites from Calotropis procera (Aiton) [PDF]

, 2010
Three new metabolites, 5-hydroxy-3,7-dimethoxyflavone-4′-O-β-glucopyranoside (1), 2β,19-epoxy-3β,14β-dihydroxy-19-methoxy-5α-card-20(22)-enolide (4) and β-anhydroepidigitoxigenin-3β-O-glucopyranoside (5), along with two known compounds, uzarigenine (2 ...
Imhoff, Johannes F., Morsy, Nagy, Schneider, Bernd, Shaker, Kamel H., Zinecker, Heidi   +4 more
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Euphorbia-derived natural products with potential for use in health maintenance [PDF]

, 2019
Euphorbia genus (Euphorbiaceae family), which is the third largest genus of angiosperm plants comprising ca. 2000 recognized species, is used all over the world in traditional medicine, especially in the traditional Chinese medicine. Members of this taxa
Adedoyin, Aleksandrov, Bard, Barla, Baslas, Chanda, Colley, Cui, Dabholkar, Deveci, Gaioni, Govaerts, Gupta, Hargreaves, Hassan, Jing, Kumara Swamy, Li, Lu, Ma, Mali, Mali, Merza, Mir, Ogbulie, Ogunlesi, Pascal, Polygenis-bigendako, Ram, Rehman, Shamsabadipour, Sharanappa, Suffness, Özbilgin, Özbilgin   +34 more
core   +4 more sources

iMet: A computational tool for structural annotation of unknown metabolites from tandem mass spectra [PDF]

, 2016
Untargeted metabolomic studies are revealing large numbers of naturally occurring metabolites that cannot be characterized because their chemical structures and MS/MS spectra are not available in databases. Here we present iMet, a computational tool based on experimental tandem mass spectrometry that could potentially allow the annotation of ...
arxiv   +1 more source