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Cell Lineage, Self-Renewal, and Epithelial-to-Mesenchymal Transition during Secondary Neurulation [PDF]
Journal of Korean Neurosurgical Society, 2021 Secondary neurulation (SN) is a critical process to form the neural tube in the posterior region of the body including the tail. SN is distinct from the anteriorly occurring primary neurulation (PN); whereas the PN proceeds by folding an epithelial neural plate, SN precursors arise from a specified epiblast by epithelial-to-mesenchymal transition (EMT),
Teruaki Kawachi +2 more
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Overview of Secondary Neurulation [PDF]
Journal of Korean Neurosurgical Society, 2021 Secondary neurulation is a morphological process described since the second half of the 19th century; it accounts for the formation of the caudal spinal cord in mammals including humans. A similar process takes place in birds. This form of neurulation is caused by the growth of the tail bud region, the most caudal axial region of the embryo ...
Martin Catala
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In Vivo Analysis of the Mesenchymal-to-Epithelial Transition During Chick Secondary Neurulation [PDF]
, 2020 The neural tube in amniotic embryos forms as a result of two consecutive events along the anteroposterior axis, referred to as primary and secondary neurulation (PN and SN). While PN involves the invagination of a sheet of epithelial cells, SN shapes the caudal neural tube through the mesenchymal-to-epithelial transition (MET) of neuromesodermal ...
Elena, Gonzalez-Gobartt +3 more
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Secondary neurulation: Fate‐mapping and gene manipulation of the neural tube in tail bud [PDF]
Development, Growth & Differentiation, 2011 The body tail is a characteristic trait of vertebrates, which endows the animals with a variety of locomotive functions. During embryogenesis, the tail develops from the tail bud, where neural and mesodermal tissues make a major contribution. The neural tube in the tail bud develops by the process known as secondary neurulation (SN), where mesenchymal ...
Eisuke, Shimokita, Yoshiko, Takahashi
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Disorders of Secondary Neurulation : Mainly Focused on Pathoembryogenesis [PDF]
Journal of Korean Neurosurgical Society, 2021 Recent advancements in basic research on the process of secondary neurulation and increased clinical experience with caudal spinal anomalies with associated abnormalities in the surrounding and distal structures shed light on further understanding of the pathoembryogenesis of the lesions and led to the new classification of these dysraphic entities. We
Jeyul Yang +3 more
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Junctional Neurulation : A Junction between Primary and Secondary Neural Tubes [PDF]
Journal of Korean Neurosurgical Society, 2021 Recent case reports of junctional neural tube defect (JNTD) which is a peculiar type of spinal anomaly showing the functional disconnection of the primary and secondary neural tubes has risen interest in the process of junctional neurulation (the connection between the two neural tubes) during development.
Kyung Hyun Kim, Ji Yeoun Lee
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Secondary Neurulation Defects-1 : Retained Medullary Cord [PDF]
Journal of Korean Neurosurgical Society, 2020 Retained medullary cord (RMC) is a relatively recent term. Pang et al. newly defined the RMC as a late arrest of secondary neurulation leaving a non-functional vestigial portion at the tip of the conus medullaris. RMC, which belongs to the category of closed spinal dysraphism, is a cord-like structure that is elongated from the conus toward the cul-de ...
Kyung Hyun Kim +2 more
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Perspectives : The Role of Clinicians in Understanding Secondary Neurulation [PDF]
Journal of Korean Neurosurgical Society, 2021 During the last two decades, there have been remarkable advances in knowledge regarding secondary neurulation. An increased number of cases of occult spinal dysraphism and progress in basic embryology research have provoked the continuous discovery of new disease entities and the reclassification of occult spinal dysraphic lesions.
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Three‐dimensional visualization of secondary neurulation in chick embryos using
Developmental Dynamics, 2021 AbstractBackgroundDefects in secondary neurulation play an important role in neural tube defects. Researchers have investigated the processes of secondary neurulation and caudal body formation mainly by microscopic observations and molecular experiments.
Sejin Choi +4 more
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Effects of Alcohol During Secondary Neurulation in Chick Embryos
Journal of Dr Behcet Uz Children s Hospital, 2017 Objective: Alcohol continues to be consumed even though its harmful effecs are well established. One of the most common damage of alcohol consumption is fetal alcohol syndrome, characterized by craniofacial anomalies, cardiac anomalies and neural tube defects.
Mehmet İbrahim Tuğlu +5 more
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